PedAM
Pediatric Disease Annotations & Medicines
| Disease | hereditary hemorrhagic telangiectasia |
| Symptom | C0016169|fistula |
| Sentences | 2 |
| PubMedID- 23316313 | It has been reported by several groups that the intravenous microbubble injection during transcranial doppler (tcd) ultrasound examination provoked aura and headache in some migraine patients with aura and pfo, accounting for up to 15% of the patients examined in some series.9–11 similarly, cerebral embolism during pfo closure led to migraine attacks shortly after the intervention.2 moreover, a prospective study showed that pfo closure could decrease the frequency and severity of attacks in migraine patients without previous stroke when patients were selected based on magnetic resonance (mr) evidence of cerebral embolism.6,12 improvement in migraine after pulmonary fistula closure in patients with hereditary hemorrhagic telangiectasia further supports the link between cerebral embolism and migraine attacks.13 paradoxical microembolism may therefore be a triggering factor for some attacks in a subgroup of ma patients.12 large pfos associated with atrial aneurysms or the presence of prothrombotic hematologic factors or conditions that are increasing intrathoracic pressure may predispose these patients to cerebral microembolism, similar to stroke patients with postulated paradoxical embolism.14–16 interestingly, a majority of the cerebellar infarct–like lesions detected on mr images of young migraine patients were located in the vascular border zone territory,17 suggesting a microembolic origin,18 although the pathology of these mr lesions remains to be verified. |
| PubMedID- 22850501 | Giant calcified thrombosed varices secondary to a pial arteriovenous fistula associated with hereditary hemorrhagic telangiectasia. |
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