PedAM
Pediatric Disease Annotations & Medicines
| Disease | hepatocellular carcinoma |
| Symptom | C0009450|infection |
| Sentences | 73 |
| PubMedID- 22216150 | The pre-s2δ type of hbv large surface mutant protein is predominant in hepatocellular carcinoma patients with hbv infection , . |
| PubMedID- 21827734 | Background & aims: hepatitis b virus (hbv) genotype c infection is associated with progression of hepatocellular carcinoma (hcc). |
| PubMedID- 20107884 | It is well known that telomerase activation and virus infection are strongly associated with human hepatocellular carcinoma (hcc). |
| PubMedID- 24895808 | Background/aims: this study was carried out to clarify the clinicopathological features of hepatocellular carcinoma (hcc) arising in patients without viral infection and to confirm the influence of metabolic syndrome (ms) on characteristics in hcc patients. |
| PubMedID- 24593285 | Hcv infection can lead to liver cirrhosis, hepatocellular carcinoma and death. |
| PubMedID- 25857645 | Two studies have reported that alcohol is associated with the presence of severe liver disease and the development of hepatocellular carcinoma in patients with an hbv infection . |
| PubMedID- 25446333 | Chronic hepatitis c virus (hcv) infection increases the risk of liver cirrhosis and hepatocellular carcinoma. |
| PubMedID- 21272924 | Overexpression of thy1/cd90 in human hepatocellular carcinoma is associated with hbv infection and poor prognosis. |
| PubMedID- 22347882 | hepatocellular carcinoma associated with hcv infection is not only caused by chronic inflammation, but also by the biological activity of hcv proteins. |
| PubMedID- 21278701 | The incidence of hepatocellular carcinoma associated with hepatitis c infection decreased in kyushu area. |
| PubMedID- 26532675 | Social burden of chronic hcv infection in patients with hepatocellular carcinoma. |
| PubMedID- 24759835 | More than 80% of hepatocellular carcinomas (hcc) are associated with chronic infection caused by hepatitis b or c virus 1. |
| PubMedID- 20133632 | Hcv infection can lead to cirrhosis, hepatocellular carcinoma, and end-stage liver disease, as well as extrahepatic complications such as cryoglobulinemia and lymphoma. |
| PubMedID- 21212947 | The hepatitis b virus x (hbx) protein is well known for its role in hepatitis b virus infection that often leads to hepatocellular carcinoma. |
| PubMedID- 22170748 | Indeed, hcv infection increases rates of hepatocellular carcinoma via the accumulation of senescent hepatocytes in human liver . |
| PubMedID- 23213040 | Chronic hepatitis b virus (hbv) infection leads to cirrhosis and hepatocellular carcinoma (hcc). |
| PubMedID- 23166538 | Results: the current belief is that the increased incidence of hepatocellular carcinoma is because of co-infection with the two viruses, one known to be hepatocarcinogenic and the other suspected to increase the carcinogenic potential of the other. |
| PubMedID- 20492708 | The risk for hepatocellular carcinoma is increased in patients with liver viral infection and iron overload 5. |
| PubMedID- 20305313 | Main indications for orthotopic liver transplantation were cholestatic liver disease (31%), viral-induced cirrhosis (25%), alcoholic liver disease (19%), hepatocellular carcinoma associated with hepatitis virus infection (13%), autoimmune cirrhosis (6%), cryptogenic acute liver failure (6%). |
| PubMedID- 19935643 | Chronic hepatitis c viral infection can lead to cirrhosis and hepatocellular carcinoma. |
| PubMedID- 21809355 | We aimed to investigate the incidence of occult hepatitis b infection (obi) in patients with "cryptogenic" hepatocellular carcinoma (hcc) and to study the hbv replicative activity in these patients. |
| PubMedID- 19787285 | Background/purpose: the majority of hepatocellular carcinomas are associated with chronic infection with hepatitis b or c virus. |
| PubMedID- 22081179 | Chronic hepatitis b and c virus infection can lead to cirrhosis and hepatocellular carcinoma. |
| PubMedID- 23250907 | Enhancers and attenuators of risk associations of chronic hepatitis b virus infection with hepatocellular carcinoma in type 2 diabetes. |
| PubMedID- 24212236 | Hbv can cause acute and persistent infection which can lead to hepatocellular carcinoma (hcc). |
| PubMedID- 23528527 | Cross-sectional studies have showed a marked increase in the prevalence of occult hepatitis b infection (obi) in patients with cirrhosis or hepatocellular carcinoma. |
| PubMedID- 24648807 | However, a chronic hepatitis b virus (hbv) infection associated with dermatomyositis and hepatocellular carcinoma (hcc) has been very rarely reported. |
| PubMedID- 20338549 | Despite the cost and side effects of this treatment regimen, many patients fail this therapy and develop persistent hcv infection, leading to cirrhosis and hepatocellular carcinoma. |
| PubMedID- 26053031 | For example, a high hepatitis b virus (hbv) load and chronic hepatitis b (chb) infection increases the risk of developing hepatocellular carcinoma. |
| PubMedID- 25001174 | Persistent infection can lead to cirrhosis and hepatocellular carcinoma. |
| PubMedID- 24704525 | Background & aims: treatment for hepatitis b virus infection reduces the risk of hepatocellular carcinoma (hcc). |
| PubMedID- 26544179 | It has been reported that the gstp1 gene is hypermethylated in genotype 1b hcv core protein-positive cells and in hepatocellular carcinoma (hcc) tumors associated with hcv infection . |
| PubMedID- 24946348 | This report highlights a rare case of concurrent hepatitis b and liver fluke infection with hepatocellular carcinoma, presenting clinically as a diagnostic and surgical challenge. |
| PubMedID- 24220021 | About 6% of the world’s population (378 million) are chronic carriers of hbv, and approximately 1 million people die each year from complications such as cirrhosis and hepatocellular carcinoma (hcc) arising from hbv infection 1. |
| PubMedID- 26272175 | The immunological mechanisms by which hepatitis b virus (hbv) initiates and maintains acute or chronic infection, even the formation of cirrhosis and hepatocellular carcinoma, are still undefined. |
| PubMedID- 25735368 | Serum biomarkers for early detection of hepatocellular carcinoma associated with hcv infection in egyptian patients. |
| PubMedID- 24118072 | Chronic hbv infection increases the risk of liver cirrhosis and hepatocellular carcinoma. |
| PubMedID- 25071320 | Globally, at least one third of hepatocellular carcinoma cases are attributed to hcv infection, and 350000 people died from hcv related diseases per year. |
| PubMedID- 20502631 | Hepatitis c virus (hcv) causes a persistent infection that can lead to hepatocellular carcinoma and liver cirrhosis. |
| PubMedID- 23782341 | Objectives: the impact of pre-transplant hepatitis b virus (hbv) and/or hepatitis c virus (hcv) infection in patients with hepatocellular carcinoma (hcc) is not well described. |
| PubMedID- 24801353 | The townships where the participants resided were endemic areas of hcv infection with high hepatocellular carcinoma mortality rates. |
| PubMedID- 24321500 | The role of hbv infection in the cause of hepatocellular carcinoma is further confirmed when taiwanese hbv immunization programme significantly reduced the cancer incidence in vaccinated children compared to non-vaccinated children . |
| PubMedID- 21374690 | Occult and previous hepatitis b virus infection are not associated with hepatocellular carcinoma in united states patients with chronic hepatitis c. |
| PubMedID- 26301052 | Hepatitis c infection can lead to cirrhosis and hepatocellular carcinoma and it is an important cause of mortality and morbidity. |
| PubMedID- 20166172 | This study sought to identify independent risk factors involved in development of hepatocellular carcinoma (hcc), particularly in patients with chronic hbv infection who have normal alt values. |
| PubMedID- 26186510 | The mechanism of hepatocellular carcinoma in patients with liver fluke infection remains unknown. |
| PubMedID- 24652769 | Another study has revealed the presence of concurrent methylation of groups of genes in hepatocellular carcinomas that are associated with infection with the hepatitis b or hepatitis c virus, suggesting that aberrant epigenetic changes that are associated with viral infection and exposure to environmental factors might activate events that promote the neoplastic transformation of hepatocytes (lambert et al., 2011). |
| PubMedID- 22028976 | For younger individuals with chronic hepatitis b virus infection, the annual risk of hepatocellular carcinoma development is lower than the threshold of 0.2%, but the disease is often more aggressive . |
| PubMedID- 23202463 | Ultimately, the chronic infection leads to hepatocellular carcinoma formation in nearly 3-5% of viral-infected patients. |
| PubMedID- 22086888 | By contrast, hepatitis b may convert to a chronic infection that leads to cirrhosis and hepatocellular carcinoma, underscoring the importance of vaccinations in at-risk individuals. |
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