PedAM

Pediatric Disease Annotations & Medicines

Disease	heart disease
Symptom	C0020443\|hypercholesterolemia
Sentences	8
PubMedID- 25887906	He is a known hypertension and hypercholesterolemia patient with ischemic heart disease for 3 years.
PubMedID- 22783203	#adjusted for age (70–74, 75–79, 80–84, and 85+ years), sex, body mass index, hypertension, hypercholesterolemia, diabetes, history of coronary heart disease, history of stroke, history of renal disease, history of hepatic disease, drinking status, smoking status, physical activity, physical performance, depressive symptoms, mini-mental state examination, and use of tranquilizers.
PubMedID- 26161751	Untreated hypercholesterolemia was inversely associated with coronary heart disease, but it was not significantly associated with other cardiovascular disease and risk factors in table 1.
PubMedID- 23656797	hypercholesterolemia is strongly associated with coronary heart disease .
PubMedID- 20730067	Presently, the prevalence of coronary artery disease is still low in africa.31 however, the risk factors of hypertension, obesity, and hypercholesterolemia associated with coronary heart disease are emerging.32 the percentage of obese patients (bmi > 30) in this study was 40% for females and 16% for males.
PubMedID- 21822496	Ironically, the apo e4 allele is associated with hypercholesterolemia and greater risk of ischemic heart disease, whereas the apo e2 allele is considered a protective factor against the development of this disorder .
PubMedID- 22010136	Mirroring these results, the apolipoprotein e4/e4 genotype was also associated with lower coronary heart disease risk in patients with familial hypercholesterolemia with an ldlr mutation (hazard ratio, 0.26; hazard ratio, 0.08-0.80; p=0.02).
PubMedID- 23056485	Based on echocardiographic data, an early cardiomyopathy characterized by systolic and diastolic dysfunction was described in patients with primary hypercholesterolemia without evidence of coronary heart disease 1.

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