PedAM
Pediatric Disease Annotations & Medicines
| Disease | gastric cancer |
| Symptom | C0850666|h. pylori infection |
| Sentences | 17 |
| PubMedID- 23874414 | Another study showed hypermethylation of cox-2 promoter paralleled by dnmt1 overexpression in gastric cancers associated with h. pylori infection . |
| PubMedID- 24162382 | Thus, it was confirmed that most gastric cancer is associated with h. pylori infection and that the disease can be effectively prevented by eradication of this microorganism. |
| PubMedID- 22970268 | These events suggest that anxa4 could mediate the downstream signal pathway, leading to tumorigenesis in gastric cancer patients with a h. pylori infection. |
| PubMedID- 26464767 | Mucosal il-6 levels were also higher in early gastric cancer with active h. pylori infection than without h. pylori infection, and the levels decreased dramatically after eradication of infection (25). |
| PubMedID- 25915048 | In conclusion, the incidence of metachronous gastric cancer was higher in patients with persistent h. pylori infection than in those whose h. pylori infection was eradicated. |
| PubMedID- 23365642 | An estimated 75% of all gastric cancer cases are associated with h. pylori infection 2. |
| PubMedID- 21418558 | The development of gastric cancer is mainly associated with h. pylori infection leading to a focus in pathology studies on bacterial and environmental factors, and to a lesser extent on the mechanistic development of the tumour. |
| PubMedID- 23661025 | In this inflammatory condition the immune cells try to kill bacterial cells and synthesize large amounts of free radicals and aldehydes and gastric cells are exposed to these radicals, gastric juice, n-nitroso compounds, which are thought to play a secondary, after caga, role in the development of gastric cancer associated with h. pylori infection 2. |
| PubMedID- 24216700 | Established tgf-β2 dominant-negative mice (mixed c57bl/6 × sv/129 background) under the tff1 promoter, and these mice showed a higher proliferation index and a higher incidence of gastric cancer with h. pylori infection . |
| PubMedID- 24454004 | Smoking is known to elevate the risk of gastric cancer, synergistically with h. pylori infection 3. |
| PubMedID- 21841827 | We previously reported that h. pylori infection of gastric cancer cells in vitro and in vivo is associated with p27 loss and resistance to apoptosis (eguchi et al 2004, kim et al 2006, shirin et al 2000). |
| PubMedID- 23560148 | We have recently reported that infliximab, a monoclonal antibody against tnf-α, can prevent the development of colitis-associated colorectal cancers in rodents.63 besides these synthetic products, a large body of evidence suggests that regular consumption of fruits and vegetables can prevent different forms of gi cancers (table 1).74-132 because it is estimated that two thirds to three quarters of gastric cancer worldwide are associated with h. pylori infection,133 it seems that the eradication of h. pylori and the control of gastric inflammation induced by the pathogen are essential in the prevention of gastric cancer. |
| PubMedID- 23168708 | We analyzed p53, k-ras gene mutation and h. pylori infection in patients with gastric cancer and peptic ulcer disease and compared it with non-ulcer dyspepsia which is considered as disease control group. |
| PubMedID- 26401131 | It is belived that roughly 65–80% of gastric cancers are associated with h. pylori infection. |
| PubMedID- 23077566 | An elevated risk of gastric cancer was observed in patients with h. pylori infection, smoking, or alcohol consumption, and together with the gstp1 ile/val +val/val genotype (or = 3.696; 95% ci = 2.475–5.521; or = 1.638; 95% ci = 1.044–2.571; or = 1.641; 95% ci = 0.983–2.739, respectively) (p<0.05). |
| PubMedID- 23152856 | We found that aqp3 expression in gastric cancer tissues correlated with h. pylori infection status, and h. pylori upregulated aqp3 expression in human gastric adenocarcinoma cells in vitro via the extracellular signal-regulated kinase (erk) signaling pathway, confirmed by experimental gastric helicobacter infection in rats. |
| PubMedID- 22515361 | Some studies have indicated a strong association between the endoscopically observed extent of chronic atrophic fundic gastritis (cafg) and increased risk of development of gastric cancer in patients with h. pylori infection . |
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