PedAM
Pediatric Disease Annotations & Medicines
| Disease | gastric cancer |
| Symptom | C0009450|infection |
| Sentences | 83 |
| PubMedID- 23168708 | We investigated the association of p53 and k-ras gene mutation and helicobacter pylori infection in patients with gastric cancer (gc) and peptic ulcer disease (pud) attending a tertiary care hospital in north india. |
| PubMedID- 22086490 | Pylori infection doubles the risk of developing gastric cancer. |
| PubMedID- 26314671 | gastric cancer risk in patients with helicobacter pylori infection and following its eradication. |
| PubMedID- 23776537 | In addition, h. pylori infection increased the risk of developing gastric cancer (or = 1.51, 95%ci = 1.07–2.13). |
| PubMedID- 25823664 | Ndrg2 promoter methylation was associated with h. pylori infection and worse prognosis of gastric cancer patients, which is an independent prognostic factor for the disease-free survival (dfs). |
| PubMedID- 22890997 | Helicobacter pylori infection is associated with gastritis and gastric cancer. |
| PubMedID- 22076182 | (5) it has been reported that in the population with h. pylori infection, the incidence of gastric cancer is higher in the cytotoxin-associated gene a (caga)-positive group. |
| PubMedID- 22235320 | The interaction between the il10-592 genetic variant and h. pylori infection on the risk of intestinal-type gastric cancer was statistically significant (p for interaction = 0.047). |
| PubMedID- 25875960 | Compared with the patients without h. pylori infection and family histories of gastric cancer, both the protein and mrna levels of fiht significantly decreased in patients with h. pylori infection and/or family histories of gastric cancer, and both the protein and mrna levels of il-8 significantly increased. |
| PubMedID- 20637122 | How h.pylori infection leads to gastric cancer is not yet completely clear, as a variety of pathogenic factors may act on different stages, such as virulence factors, dna damage, host factors and cox-2. |
| PubMedID- 22174720 | Several case series of gastric cancer associated with s. japonicum infection have been published from both china and japan (reviewed in ). |
| PubMedID- 21871583 | Helicobacter pylori infection is associated with gastric cancer (gc). |
| PubMedID- 22353533 | Background/aims: there have been few reports comparing pre and postoperative prevalence of helicobacter pylori infection and gastritis in patients with gastric cancer surgery. |
| PubMedID- 22139978 | Aim: helicobacter pylori infection, though common, leads to gastric cancer (gc) in less than 1% individuals, suggesting the role of host factors. |
| PubMedID- 21791582 | A direct association between h. pylori and the gastric progenitor cells could have implications for the increased gastric cancer associated with h. pylori infection (15), so evaluation of chepep’s role in animal models of carcinogenesis will be important for future studies. |
| PubMedID- 26239415 | Transforming growth factor beta 1 (tgf-beta1) modulates epstein-barr virus reactivation in absence of helicobacter pylori infection in patients with gastric cancer. |
| PubMedID- 24413205 | Conclusion: a weak significant difference existed between the frequency of helicobacter pylori infection in patients with the proximal gastric cancer and the frequency of these infections in the patients with the distal cancer. |
| PubMedID- 23607896 | Pylori) infection is etiologically associated with gastric cancer and peptic ulcer diseases which are both important public health burdens which could be largely eliminated by h. |
| PubMedID- 21466786 | Pylori infection promoted methylation of wwox gene in gastric cancer. |
| PubMedID- 24553293 | Pylori) infection is strongly associated with gastric cancer. |
| PubMedID- 22515361 | Some studies have indicated a strong association between the endoscopically observed extent of chronic atrophic fundic gastritis (cafg) and increased risk of development of gastric cancer in patients with h. pylori infection . |
| PubMedID- 24041200 | First, we did not obtain the h. pylori status and also had no information on whether the patients ever received h. pylori eradication before 1997. h. pylori infection is associated with gastric cancer development, and early eradication of h. pylori can reduce the risk of gastric cancer . |
| PubMedID- 24216700 | However, mice lacking mlh1 or msh2 do not develop gastric cancer, even with h. felis infection (fox jg and wang tc, unpublished data). |
| PubMedID- 21418558 | The development of gastric cancer is mainly associated with h. pylori infection leading to a focus in pathology studies on bacterial and environmental factors, and to a lesser extent on the mechanistic development of the tumour. |
| PubMedID- 26552450 | H. pylori has been classified as group 1 carcinogen by the international agency for research on cancer since 1994 because many studies have proven the association between h. pylori infection and development of gastric cancer, especially intestinal type non-cardiac gastric cancer . |
| PubMedID- 26215613 | Impact of intra-operative intraperitoneal chemotherapy on organ/space surgical site infection in patients with gastric cancer. |
| PubMedID- 24037736 | Background and objectives: gastric cancer patients with helicobacter pylori infection had been reported to have a better prognosis. |
| PubMedID- 23346103 | Researchers are needed to further elucidate how h. pylori infection increases the risk of gastric cancer. |
| PubMedID- 23209350 | The tnf-a-308a genotype is therefore associated with h. pylori infection and increased risk of gastric cancer (10, 15, 16, 17, 18). |
| PubMedID- 25437333 | Mongolian gerbils have been extensively used for investigating h. pylori-induced gastritis which can result in gastric cancer with longer term infection . |
| PubMedID- 26176534 | Chronic helicobacter pylori infection is associated with gastric cancer . |
| PubMedID- 23577028 | In gastric cancer associated with helicobacter pylori infection, oncogenic transformation evolves through progressive stages starting with an inflammatory gastritis, followed by metaplasia, dysplasia, and finally cancer . |
| PubMedID- 24498543 | Chronic gastric inflammation, which is often provoked by helicobacter pylori persistent infection, increases the risk of developing of gastric cancer, at least in part by altering the growth and differentiation of the gastric epithelium. |
| PubMedID- 22901223 | Objective: to investigate the association between the connexin 37 c1019t polymorphism and helicobacter pylori infection in patients with gastric cancer. |
| PubMedID- 23077566 | An elevated risk of gastric cancer was observed in patients with h. pylori infection, smoking, or alcohol consumption, and together with the gstp1 ile/val +val/val genotype (or = 3.696; 95% ci = 2.475–5.521; or = 1.638; 95% ci = 1.044–2.571; or = 1.641; 95% ci = 0.983–2.739, respectively) (p<0.05). |
| PubMedID- 25663919 | However, no significant interaction was identified between the rs763780 polymorphism and cigarette smoking or h. pylori infection in the risk of developing gastric cancer. |
| PubMedID- 23874414 | Another study showed hypermethylation of cox-2 promoter paralleled by dnmt1 overexpression in gastric cancers associated with h. pylori infection . |
| PubMedID- 23049225 | Cpg island methylator phenotype and helicobacter pylori infection associated with gastric cancer. |
| PubMedID- 24516778 | Examples of such association include helicobacter pylori infection with gastric cancer, hbv and hcv infections with hepatocellular carcinoma (hcc), and chronic inflammatory bowel diseases (ibd) with colorectal cancer (crc).10-12 yet the majority of cancers that are not associated with preceding inflammation contain inflammatory infiltrates. |
| PubMedID- 23365642 | An estimated 75% of all gastric cancer cases are associated with h. pylori infection 2. |
| PubMedID- 20309944 | Helicobacter pylori infection is associated with gastric cancer. |
| PubMedID- 25254613 | Background & aims: patients with epstein-barr virus-associated gastric carcinoma (ebvagc) have a better prognosis than those with gastric cancer not associated with ebv infection (ebvngc). |
| PubMedID- 22481686 | Atrophy, intestinal metaplasia and gastric cancer have been associated with infection by helicobacter pylori. |
| PubMedID- 22518340 | Since marshall and warren 2, who discovered helicobacter pylori and reported its infection closely associated with gastric cancer development, won the nobel prize in physiology or medicine in 2005, there have been an increasing number of reports on pubmed as to the relationship between inflammation and carcinogenesis in a variety of tissues (table 1) and it has been featured in major journals. |
| PubMedID- 24050512 | In addition, european guidelines recommend eradicating h. pylori infection in first-degree relatives of patients with gastric cancer, in long term nsaids or acid suppression users and in patients with functional dyspepsia 4. |
| PubMedID- 23560148 | Significant reduction in colonic adenomas in patients receiving a combination of diferuloylmethane, polyamine biosynthesis inhibitor, and sulindac suggest that increased polyamine synthesis contributes to colon carcinogenesis.43 gobert et al.44 reported that h. pylori infection, the major cause of gastric cancer, induces the expression and activity of enzymes utilized for polyamine biosynthesis. |
| PubMedID- 23251807 | However, the current study found that most of these gastric cancers were not associated with helicobacter pylori infection which is considered as one of the main cause of the gastric cancer. |
| PubMedID- 26087794 | Pylori infection status of 705 resectable gastric cancer patients was determined by the rapid urease test, testing for anti-h. |
| PubMedID- 26089643 | Chronic helicobacter pylori infection is associated with gastric cancer and mucosa-associated lymphoid tissue lymphoma; chlamydia trachomatis infection increases the risk of cervical cancer;27 enterotoxigenic bacteroides fragilis infection promotes colon tumorigenesis.28 viral infections by high-risk human papillomavirus (hpv) subtypes, such as hpv16 and hpv18, are causal to the development of cervical, anal, and genital cancers.29,30 infections with hepatitis b or c viruses increase the risk of hepatocellular carcinoma;31 the epstein–barr virus can cause lymphomas and nasopharyngeal cancer;32 human herpes virus 8 (also known as kaposi sarcoma-associated herpes virus) causes kaposi sarcoma;33 hiv infection has been linked to a higher risk of developing kaposi sarcoma and cervical cancer;34 human t-lymphotrophic virus-1 has been linked with adult t-cell leukemia/lymphoma;35 merkel cell polyomavirus causes merkel cell carcinoma.36 schistosomiasis is associated with the development of bladder cancer;37opisthorchis viverrini and clonorchis sinensis infection are linked to increased risk of cholangiocarcinoma.38 microorganisms may manipulate and/or collaborate with cellular signaling pathways to promote an inflammatory microenvironment that facilitates cancer development. |
| PubMedID- 22776172 | A case of helicobacter pylori infection complicated with gastric cancer, gastric mucosa-associated lymphoid tissue lymphoma, and idiopathic thrombocytopenic purpura successfully treated with laparoscopy-assisted total gastrectomy and splenectomy. |
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