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PedAM

Pediatric Disease Annotations & Medicines




Disease fibrous dysplasia
Symptom C1608408|malignant transformation
Sentences 7
PubMedID- 25565743 Reported a similar case of fibrous dysplasia revealing malignant transformation that occurs in less than 1% of cases, with a mean lag period of 13.5 years.
PubMedID- 23961498 Though not common, malignant transformation of fibrous dysplasia can also occur as part of mazabraud syndrome.
PubMedID- 25958111 Although malignant transformation of fibrous dysplasia is rare, early diagnosis and adequate treatment may lead to favorable prognosis 3.
PubMedID- 24381897 Overexpression of p53 protein has been reported in fibrous dysplasia with malignant transformation.
PubMedID- 24959281 malignant transformation of fibrous dysplasia (fd) is rare (1–4).
PubMedID- 23074969 Among 266 patients, 3 patients (3/266, 1.1%) were found to undergo spontaneous malignant transformation of fibrous dysplasia into osteosarcoma which were confirmed by postoperative pathological examinations as evidenced by the existence of both fibrous dysplasia and osteosarcoma.
PubMedID- 25621678 malignant transformation in fibrous dysplasia (fd) is uncommon.

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