PedAM
Pediatric Disease Annotations & Medicines
| Disease | epilepsy |
| Symptom | C0679466|cognitive deficits |
| Sentences | 9 |
| PubMedID- 24287913 | Gabaergic neurons were isolated from patients of dravet syndrome, which is a devastating infantile-onset epilepsy syndrome with cognitive deficits and autistic traits caused by genetic alterations in sodium channels. |
| PubMedID- 23639079 | Background: dravet syndrome is a devastating infantile-onset epilepsy syndrome with cognitive deficits and autistic traits caused by genetic alterations in scn1a gene encoding the alpha-subunit of the voltage-gated sodium channel na(v)1.1. |
| PubMedID- 23858325 | This paper reviews the clinical implications of topiramate (tpm)-induced cognitive deficits in patients with epilepsy, migraine headache, obesity, and in normal populations, followed by reviews of the literature describing the reversal of such deficits upon medication discontinuation. |
| PubMedID- 26337111 | The aim of this review is to (1) define the nature of cognitive deficits associated with epilepsy, (2) review fundamental systems-level mechanisms underlying information processing, and (3) describe how information processing is dysfunctional in epilepsy and investigate the relative contributions of etiology, seizures, and interictal discharges (ids). |
| PubMedID- 25982500 | Abnormalities in connectivity, particularly in dorsal attention (dan), salience (sn) and default mode (dmn) networks, might contribute to the loss of consciousness during seizures and cognitive deficits in patients with children absence epilepsy (cae). |
| PubMedID- 24587054 | Understanding when and how acth is effective in improving cognition may lead to new treatments for cognitive deficits associated with pediatric epilepsy that are independent of the treatment of seizures. |
| PubMedID- 20716372 | Kirsch proposed an alternative view, linking psychosocial disturbances in epilepsy with subtle cognitive deficits. |
| PubMedID- 23166829 | epilepsy itself can lead to cognitive deficits in brain tumor patients . |
| PubMedID- 26316868 | The following are the key points of this review: autism spectrum disorders and social-cognitive deficits are associated with epilepsy throughout the life-span, and identification of these deficits is an important part of epilepsy care.children with an epileptic encephalopathy such as infantile spasms are at high risk for developing asd, and the social-cognitive deficits that precede asd may be recognized in the first year of life.in epilepsy, the likelihood of developing autism spectrum disorders is highest in those with id, but there is a wide spectrum of manifestations, from asd in children with epilepsy and id, to social-cognitive impairments affecting social interaction and comprehension in those with normal nonsocial cognitive function.implementation of behavioral, communication, and educational interventions that exist to treat asd and social-cognitive deficits, along with medications to treat the seizures, should be considered an important part of the comprehensive management of epilepsy throughout the life-span. |
Page: 1