PedAM
Pediatric Disease Annotations & Medicines
| Disease | eosinophilia |
| Symptom | C0027022|myeloid neoplasm |
| Sentences | 15 |
| PubMedID- 21054467 | A case of myeloid neoplasm associated with eosinophilia and kiaa1509-pdgfrbeta responsive to combination treatment with imatinib mesylate and prednisolone. |
| PubMedID- 20164181 | The fusion of tel with platelet-derived growth factor receptor (pdgfr) beta (tpbeta) is found in a subset of patients with atypical myeloid neoplasms associated with eosinophilia and is the archetype of a larger group of hybrid receptors that are produced by rearrangements of pdgfr genes. |
| PubMedID- 23085697 | Apart from mastocytoses, immunophenotypically aberrant tissue mast cells are only observed in certain rare forms of myeloid neoplasms with eosinophilia, in particular in myeloproliferative neoplasms (mpn-eo) with cytogenic anomalies in the platelet-derived growth factor receptor (pdgfr). |
| PubMedID- 25175494 | Relapse of myeloid neoplasm with eosinophilia and pdgfra rearrangement after imatinib discontinuation in a pediatric patient. |
| PubMedID- 23156891 | Chronic myeloid neoplasm with eosinophilia and abnormality of platelet-derived growth factor receptor alpha (pdgfra), referred as chronic eosinophilic leukemia, is an extremely rare neoplasm where long-term prognosis is uncertain though a high grade of responsiveness to imatinib has been reported. |
| PubMedID- 23025324 | myeloid neoplasms with eosinophilia and fip1l1-pdgfra fusion gene: another point of view. |
| PubMedID- 20589620 | myeloid neoplasm with prominent eosinophilia and pdgfra rearrangement treated with imatinib mesylate. |
| PubMedID- 25658984 | In summary, this report describes a novel tnks2–pdgfra fusion that diagnostically defines a distinct category of myeloid neoplasms with eosinophilia as defined within the who 2008 classification schema. |
| PubMedID- 23208343 | myeloid neoplasm associated with eosinophilia and platelet-derived growth factor receptor-alpha rearrangement. |
| PubMedID- 23982058 | The mann-whitney test was used to compare wt1 expression levels in 3 groups of patients: patients with hes, secondary eosinophilia, and eosinophilia associated with a myeloid neoplasm. |
| PubMedID- 23489324 | myeloid neoplasms associated with eosinophilia and rearrangement of pdgfra, pdgfrb, and fgfr1: a review. |
| PubMedID- 23976869 | Two different categories of myeloid neoplasms with eosinophilia are proposed by the 2008 who classification: (1) “chronic eosinophilic leukemia cel, not otherwise specified cel-nos;”11 and (2) “the myeloid and lymphoid neoplasms with eosinophilia and abnormalities of pdgfra, pdgfrb, or fgfr1.”11 the who classification specifies that all patients with pdgfra, pdgfrb or fgfr1 abnormalities need further diagnostic evaluation to get a final diagnosis of myeloproliferative neoplasms (mpn) or another malignancy.11 the 2011 working conference’s panel of experts agreed with the cytogenetic and molecular who classification but underlined two weaknesses – the lack of histologic subclassification and the absence of subgroups with more than one driver mutation.7,8 the second mutation can be produced by a subclone, or two separate neoplasms can coexist. |
| PubMedID- 24764730 | Pdgfra-positive myeloid neoplasm with eosinophilia is a rare disease and this study indicates the need to do the pdgfra assay in patients with hes. |
| PubMedID- 23600098 | Unique association of myeloid neoplasm with eosinophilia and abnormalities of pdgfra with ttp. |
| PubMedID- 22541084 | Out of detected 2000 cases of myeloid cell abnormalities in our hospital, 12 cases of myeloid neoplasms with eosinophilia and abnormalities of pdgfrb were found. |
Page: 1