PedAM
Pediatric Disease Annotations & Medicines
| Disease | diabetes mellitus, insulin-dependent |
| Symptom | C0442874|neuropathy |
| Sentences | 43 |
| PubMedID- 23914216 | Prevalence and related risk-factors of peripheral neuropathy in children with insulin-dependent diabetes mellitus. |
| PubMedID- 22608666 | While glucose control substantially decreases the development of neuropathy in those with type 1 diabetes, the effect is probably much smaller in those with type 2 diabetes. |
| PubMedID- 23723354 | However, the transition from subclinical to clinical neuropathy in patients with type 1 diabetes has not been described previously. |
| PubMedID- 25783659 | However, adequate data is not available to determine whether regular exercise would prevent or delay the development of painful neuropathy in subjects with type 1 diabetes. |
| PubMedID- 20040653 | In addition to traditional cardiovascular disease risk factors, autonomic neuropathy (an), a complication of type 1 diabetes, is of particular interest, as it predicts cardiovascular events and mortality (7). |
| PubMedID- 21892113 | Wolfram syndrome: a rare optic neuropathy in youth with type 1 diabetes. |
| PubMedID- 25591852 | Conclusions: autonomic dysfunction is present in early stages of retinopathy, nephropathy, and peripheral neuropathy in patients with type 1 diabetes. |
| PubMedID- 21911773 | No study has compared the rate of the development of autonomic neuropathy in patients with type 1 diabetes and cd compared with those with type 1 diabetes alone. |
| PubMedID- 24211151 | Introduction: painful peripheral neuropathy in people with type 1 diabetes is a disabling and costly complication. |
| PubMedID- 23641349 | Thus, treatment with c-peptide can slow the progression of neuropathy in patients with type 1 diabetes . |
| PubMedID- 23340890 | Over the last 30 years, a marked improvement in diabetic nephropathy, retinopathy, and neuropathy was observed in patients with type 1 diabetes mellitus (t1dm) (1–3). |
| PubMedID- 22892951 | Purpose of review: to compare and contrast the evidence for the effect of glucose control on the prevention of neuropathy in type 1 diabetes mellitus (t1dm) and type 2 diabetes mellitus (t2dm). |
| PubMedID- 24567687 | insulin-dependent diabetes mellitus (iddm) is associated with autonomic neuropathy and/orcardiovascular dysregulation, which are major complications of diabetes mellitus (dm). |
| PubMedID- 25505446 | Predictors of cardiovascular autonomic neuropathy in patients with type 1 diabetes. |
| PubMedID- 23391743 | The evaluation of peripheral neuropathy in youth with type 1 diabetes. |
| PubMedID- 22030241 | Haemodynamic changes during a squat test, pulsatile stress and indices of cardiovascular autonomic neuropathy in patients with long-duration type 1 diabetes. |
| PubMedID- 20833868 | Vibration perception threshold as a measure of distal symmetrical peripheral neuropathy in type 1 diabetes: results from the dcct/edic study. |
| PubMedID- 21819228 | Pulse wave analysis and cardiac autonomic neuropathy in type 1 diabetes: a report from the pittsburgh epidemiology of diabetes complications study. |
| PubMedID- 26241393 | Purpose: we investigated the relationship between corneal subbasal nerve (sbn) plexus density, corneal sensitivity, and peripheral and cardiac autonomic neuropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 25538321 | Corneal confocal microscopy shows an improvement in small-fiber neuropathy in subjects with type 1 diabetes on continuous subcutaneous insulin infusion compared with multiple daily injection. |
| PubMedID- 23929529 | Several clinical trials have demonstrated that treating hyperglycemia, a component of the metabolic syndrome, has a significant effect on reducing the incidence of neuropathy in those with type 1 diabetes. |
| PubMedID- 25853247 | Corneal confocal microscopy detects neuropathy in patients with type 1 diabetes without retinopathy or microalbuminuria. |
| PubMedID- 26207222 | In both type one and two diabetic patients, results of the clinical investigations three years after the procedure clearly revealed that there were no significant differences in the incidence or progression of diabetes micro vascular complications in patients who had either undergone fetal liver-derived cell suspension allotransplantation or received placebo compared to the baseline (table 2).table 2presence of retinopathy,neuropathy and microalbuminuria in patients with type 1 diabetes at the baseline and 3 years following the interventiontype 1 diabetesretinopathy (baseline)totalp-valuerethinopathy (3rd year)totalp-valuenormalpdrnormalnpdrgroupsinterventioncount130130.999b111120.999b(%)100.0%.0%100.0%91.7%8.3%100.0%placebocount1611712012(%)94.1%5.9%100.0%100.0%.0%100.0%totalcount2913023124(%)96.7%3.3%100.0%95.8%4.2%100.0%neuropathy (basal)totalp-valueneuropathy (3rd year)totalp-valueno_neurophathyneuropathy+no_neurophathyneuropathy+groupsinterventioncount121130.433b102120.478b(%)92.3%7.7%100.0%83.3%16.7%100.0%placebocount1701712012(%)100.0%.0%100.0%100.0%.0%100.0%totalcount2913022224(%)96.7%3.3%100.0%91.7%8.3%100.0%microalbominuria (baseline)totalp-valuemicroalbominuria (3rd year)totalp-valueno albominuriamicroalbominuria+no albominuriamicroalbominuria+groupsinterventioncount121130.844a120120.307a(%)92.3%7.7%100.0%100.0%.0%100.0%placebocount1611711112(%)94.1%5.9%100.0%91.7%8.3%100.0%totalcount2823023124(%)93.3%6.7%100.0%95.8%4.2%100.0%apearson chi-square.bfisher’s exact test. |
| PubMedID- 25981398 | Conclusion: these data suggest that cpt is useful in early detection of peripheral neuropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 20723100 | A 5-yr follow-up nerve conduction study for the detection of subclinical diabetic neuropathy in children with newly diagnosed insulin-dependent diabetes mellitus. |
| PubMedID- 24550215 | Objective we prospectively evaluated the association between autoimmunity to autonomic nervous structures and autonomic neuropathy in type 1 diabetes in relation to clinical variables. |
| PubMedID- 24349844 | A type i diabetes mellitus patient (complicated with neuropathy and nephropathy due to severe microangiopathy) reported erythematous lesion with two blisters on her left thigh. |
| PubMedID- 20464532 | The dcct/edic (diabetes control and complications trial/ epidemiology of diabetes interventions and complications) provides a comprehensive characterization of the natural history of diabetic neuropathy in patients with type 1 diabetes and provides insight into the impact of intensive insulin therapy in disease progression. |
| PubMedID- 24846202 | Auditory neuropathy in individuals with type 1 diabetes. |
| PubMedID- 24651803 | It has been demonstrated that 1-deoxysls are cytotoxic in various model systems, and more important, they are implicated in the pathology of neuronal functional impairment in hereditary sensory and autonomic neuropathy in patients with type 1 diabetes (hsan1) (10). |
| PubMedID- 21466989 | Natural progression of cardiac autonomic neuropathy in patients with type 1 diabetes: a four-year follow-up study. |
| PubMedID- 20823346 | We have previously highlighted the importance of conventional cardiovascular risk factors in the etiology of clinical neuropathy in individuals with type 1 diabetes (9), but their association to earlier abnormalities in nerve conduction is less certain. |
| PubMedID- 24803311 | Enhanced glucose control is much more effective at preventing neuropathy in patients with type 1 diabetes than in those with type 2 disease corrected. |
| PubMedID- 25139473 | To date, tight glycemic control is the only strategy convincingly shown to prevent or delay the development of neuropathy in patients with type 1 diabetes and to slow the progression of neuropathy in some patients with type 2 diabetes. |
| PubMedID- 24629408 | Methods: the landmark study is a 4-year, two-site, natural history study of three participant groups: type 1 diabetes with neuropathy (t1w), type 1 diabetes without neuropathy (t1wo) and control participants without diabetes or neuropathy. |
| PubMedID- 23882058 | These data thus suggested that glucose variability may be important in the development of peripheral neuropathy in patients with type 1 diabetes and that the nervous system may be particularly vulnerable to glycemic variability (9). |
| PubMedID- 21256797 | Nonlinear pd2i heart rate complexity algorithm detects autonomic neuropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 25406279 | Natural history of corneal nerve morphology in mild neuropathy associated with type 1 diabetes: development of a potential measure of diabetic peripheral neuropathy. |
| PubMedID- 25251450 | Conclusion: this study suggests that corneal confocal microscopy could represent a new and non-invasive tool to investigate cardiac autonomic neuropathy in people with type 1 diabetes. |
| PubMedID- 22503144 | Peripheral neuropathy in children with type 1 diabetes. |
| PubMedID- 20040675 | The absence of similar small-fiber neuropathy in those with longstanding type 1 diabetes suggests that glycemia may not be the major determinant of small-fiber neuropathy in igt. |
| PubMedID- 24026557 | Our study shows that small-fiber dysfunction is more prevalent than large-fiber dysfunction in diabetic neuropathy after long duration of type 1 diabetes. |
| PubMedID- 25899758 | The eurodiab iddm complications study found additional correlations between neuropathy and duration of type 1 diabetes, quality of metabolic control, age, height, cigarette smoking, high-density lipoprotein cholesterol, proliferative diabetic retinopathy, and cardiovascular disease . |
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