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PedAM

Pediatric Disease Annotations & Medicines




Disease diabetes mellitus, insulin-dependent
Symptom C0022658|nephropathy
Sentences 76
PubMedID- 20693588 Background & objectives: the efficacy of the combination of angiotensin receptor blockers (arbs) and angiotensin converting enzyme (ace) inhibitors in patients of type 1 diabetes mellitus (dm) with nephropathy is debatable.
PubMedID- 25109108 Association of renin-angiotensin system genes polymorphism with progression of diabetic nephropathy in patients with type 1 diabetes mellitus.
PubMedID- 26167956 Genome-wide pathway analysis for diabetic nephropathy in type 1 diabetes.
PubMedID- 24918158 Thus, with current treatment of nephropathy in type 1 diabetes, the prognosis and loss of renal function has improved along with better control of modifiable risk factors.
PubMedID- 25634228 Conclusions/interpretation: this study demonstrates for the first time in a prospective setting the relationship between physical activity and the risk of diabetic nephropathy in patients with type 1 diabetes.
PubMedID- 26168189 Von willebrand factor, adamts13 and d-dimer are correlated with different levels of nephropathy in type 1 diabetes mellitus.
PubMedID- 20437026 The relationship of retinal vessel diameter to changes in diabetic nephropathy structural variables in patients with type 1 diabetes.
PubMedID- 21747824 Abnormal excretion of protein is a clinically relevant indicator of impending diabetes-related renal damage; however, mechanisms underlying proteinuria in diabetic nephropathy associated with type 1 diabetes mellitus (t1d) are not completely understood.
PubMedID- 24349844 A type i diabetes mellitus patient (complicated with neuropathy and nephropathy due to severe microangiopathy) reported erythematous lesion with two blisters on her left thigh.
PubMedID- 22643932 It is, however, not known whether such snps also confer susceptibility to diabetic nephropathy in patients with type 1 diabetes mellitus.
PubMedID- 25690004 Conclusions: cd is an independent risk factor for retinopathy and nephropathy in patients with type 1 diabetes.
PubMedID- 23340892 A recent study suggested that visit-to-visit variability in blood pressure was associated with the development of diabetic nephropathy in patients with type 1 diabetes (9).
PubMedID- 23858799 Introduction: the prevalence of microalbuminuria (ma), the most important early marker of incipient nephropathy in patients with type 1 diabetes mellitus (t1dm), increases during puberty, the period of exaggerated physiological insulin resistance.
PubMedID- 23346076 Obviously, the heterozygous index is high compared to the percentage of homozygous and increased from the group of non-diabetic control subjects, to type 1 diabetes (t1d) patients without diabetic nephropathy and the patients with diabetic nephropathy.
PubMedID- 24029427 We performed a genome-wide association study in a cohort of 3652 patients from the finnish diabetic nephropathy (finndiane) study with type 1 diabetes to determine whether sex-specific genetic risk factors for esrd exist.
PubMedID- 22811694 Specifically, in patients with diabetic nephropathy associated with type 1 diabetes, nisoldipine (long-acting dihydropyridine ccb) attenuates the rate of decline in glomerular filtration .
PubMedID- 21330642 Pulse pressure predicts incident cardiovascular disease but not diabetic nephropathy in patients with type 1 diabetes (the finndiane study).
PubMedID- 25032099 Although diabetic nephropathy due to type 1 diabetes mellitus (t1dm) has been studied more extensively, the vast majority of the diabetic ckd patients suffer from type 2 diabetes mellitus (t2dm).
PubMedID- 19563389 Telomere length and progression of diabetic nephropathy in patients with type 1 diabetes.
PubMedID- 23226566 Moreover, a vdr haplotype between bsmi and taqi was protective against nephropathy in patients with type 1 diabetes, although foki polymorphisms had no significant association with the nephropathy .
PubMedID- 24781861 Objective: estimation of glomerular filtration rate (egfr) is one of the current clinical methods for identifying risk for diabetic nephropathy in subjects with type 1 diabetes (t1d).
PubMedID- 23687360 Renal lesions predict progression of diabetic nephropathy in type 1 diabetes.
PubMedID- 21180245 The purpose of this study is to investigate the association of 21a/t (rs7943316) polymorphism of cat gene with advanced diabetic nephropathy in patients with type 1 diabetes in romania.
PubMedID- 21909410 Novel susceptibility locus at 22q11 for diabetic nephropathy in type 1 diabetes.
PubMedID- 20667095 Effects of mcf2l2, adipoq and sox2 genetic polymorphisms on the development of nephropathy in type 1 diabetes mellitus.
PubMedID- 25575985 Methods: the most recent childbirth of 108 consecutive type 1 diabetes patients with diabetic nephropathy and a singleton pregnancy were studied.
PubMedID- 23844944 Associations and interactions between lipid profiles, retinopathy and nephropathy in patients with type 1 diabetes: the finndiane study.
PubMedID- 20168990 Significant association was not detected between this snp and nephropathy in those with type 1 diabetes.
PubMedID- 26212019 Objective: the aim of this study was to investigate serum levels of mannose-binding lectin (mbl) in type 1 diabetes with diabetic nephropathy (dn) and persistent normoalbuminuria (pn).
PubMedID- 24688725 To this end the summit consortium has assembled and phenotyped the largest genome-wide association study (gwas) database for type 1 diabetes patients with diabetic nephropathy (dn).
PubMedID- 21876774 Methods: snps were genotyped using sequenom or taqman technologies in 1351 individuals with type 1 diabetes (651 cases with nephropathy and 700 controls without nephropathy).
PubMedID- 21660261 Showed that the restriction of dietary protein plus phosphate intake was welltolerated and maintained nutritional parameters in a satisfying range in a study of 35 type i diabetes patients with associated nephropathy .
PubMedID- 21963083 We investigated associations of allelic variations in sod1 gene with nephropathy in patients with type 1 diabetes.
PubMedID- 23130318 The diabetes control and complications trial showed that the residual secretion of serum c-peptide decreased the incidence of diabetic retinopathy and nephropathy in subjects with type 1 diabetes .
PubMedID- 22923064 Aims/hypothesis: hba(1c) variability has been shown to be an independent risk factor for nephropathy in patients with type 1 diabetes.
PubMedID- 24172700 Severe diabetic nephropathy in type 1 diabetes and pregnancy--a case series.
PubMedID- 25686570 Prevention: intensive exercise associated with reduced risk of diabetic nephropathy in patients with type 1 diabetes mellitus.
PubMedID- 20962522 Conclusion: the a allele of rs1800783 is a significant risk factor for nephropathy in individuals with type 1 diabetes, and further comprehensive studies are warranted to confirm the definitive functional variant in the nos3 gene.
PubMedID- 20490454 Ddost, prkcsh and lgals3, which encode age-receptors 1, 2 and 3, respectively, are not associated with diabetic nephropathy in type 1 diabetes.
PubMedID- 26340273 Since fibroblasts from type 1 diabetes patients (t1dm) with nephropathy exhibit increased proliferation, we studied cell viability, basal ck2 expression and activity, and response to specific ck2 inhibitors tbb (4,5,6,7-tetrabenzotriazole) and cx4945, in fibroblasts from t1dm patients either with (t1dm+) or without (t1dm-) nephropathy, and from healthy controls (n).
PubMedID- 21826596 Effects of panax notoginoside on the nephropathy in rats with type 1 diabetes mellitus.
PubMedID- 26239688 Microalbuminuria provides the earliest clinical marker of diabetic nephropathy among patients with type 1 diabetes, yet it lacks sensitivity and specificity for early histological manifestations of disease.
PubMedID- 24667182 Therefore, pemt inhibitors may be useful in the treatment of diabetic nephropathy in patients with type 1 diabetes, as well as for other er stress- and oxidative stress-related diseases.
PubMedID- 23543049 Conclusion: the association of snp loci derived from gwas in european type 1 diabetes with diabetic nephropathy was not replicated in the japanese patients with type 2 diabetes, although the erbb4 locus may have some effect also in japanese type 2 diabetes.
PubMedID- 24587794 In summary, our results show that the ppar gamma 2 polymorphism is unlikely to be associated with the development and progression of the diabetic nephropathy in patients with type 1 diabetes.
PubMedID- 25011944 Objective: renal hyperfiltration is a common abnormality associated with diabetic nephropathy in patients with type 1 diabetes (t1d).
PubMedID- 25871838 Differential gene expression in diabetic nephropathy in individuals with type 1 diabetes.
PubMedID- 23690533 For patients with diabetes, the wariness regarding use of high-protein diets is even greater, because dietary protein restriction was shown to slow the progression of nephropathy in patients with type 1 diabetes (28) and the risk of end-stage renal disease (29,30).
PubMedID- 20191117 The purpose of this study is to assess the possible association of +35a/c (rs2234694) polymorphism in sod1-gene with advanced stages of diabetic nephropathy in patients with type 1 diabetes in romania.
PubMedID- 23909911 Thus, we sought to evaluate the concordance over time of retinopathy and nephropathy in patients with type 1 diabetes during the diabetes control and complications trial.

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