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PedAM

Pediatric Disease Annotations & Medicines




Disease diabetes mellitus, insulin-dependent
Symptom C0011881|diabetic nephropathy
Sentences 54
PubMedID- 20191117 The purpose of this study is to assess the possible association of +35a/c (rs2234694) polymorphism in sod1-gene with advanced stages of diabetic nephropathy in patients with type 1 diabetes in romania.
PubMedID- 24918158 Improved prognosis of diabetic nephropathy in type 1 diabetes.
PubMedID- 20667095 Variation of creatinine and cystatin levels among female and male type 1 diabetes patients with diabetic nephropathy according to the genotypes of leu359ile variant in the mcf2l2 gene.
PubMedID- 25011944 Objective: renal hyperfiltration is a common abnormality associated with diabetic nephropathy in patients with type 1 diabetes (t1d).
PubMedID- 23877984 Research design and methods: using the nationwide finnish diabetic nephropathy (finndiane) study cohort of 4,083 patients with type 1 diabetes (mean age of 37.4 +/- 11.8 years at enrollment), we analyzed the incidence of first-ever sah events.
PubMedID- 25622104 The possible benefit of lasp1 as a biomarker is not restricted to cancer, as lasp1 is one out of 12 differentially expressed proteins that show decreased expression in cultured skin fibroblasts of insulin-dependent type 1 diabetes mellitus patients with diabetic nephropathy versus diabetics without nephropathy or healthy subjects.
PubMedID- 20490454 Ddost, prkcsh and lgals3, which encode age-receptors 1, 2 and 3, respectively, are not associated with diabetic nephropathy in type 1 diabetes.
PubMedID- 24527422 Continuous microalbuminuria (30-299 mg/day) appears in the early stages of diabetic nephropathy with type 1 diabetes, and it is an indicator of nephropathy onset and the development of cardiovascular disease 5.
PubMedID- 24781861 Objective: estimation of glomerular filtration rate (egfr) is one of the current clinical methods for identifying risk for diabetic nephropathy in subjects with type 1 diabetes (t1d).
PubMedID- 20332124 Conclusions: these findings suggest a role of inflammation and endothelial dysfunction as markers and contributors of the development of diabetic nephropathy in persons with type 1 diabetes mellitus.
PubMedID- 24029427 We performed a genome-wide association study in a cohort of 3652 patients from the finnish diabetic nephropathy (finndiane) study with type 1 diabetes to determine whether sex-specific genetic risk factors for esrd exist.
PubMedID- 25634228 Aims/hypothesis: the aim of this study was to assess how physical activity predicts the development and progression of diabetic nephropathy in patients with type 1 diabetes.
PubMedID- 23317710 The patient had a 16-year history of poorly controlled type 1 diabetes mellitus with end stage diabetic nephropathy requiring regular haemodialysis.
PubMedID- 25686570 Prevention: intensive exercise associated with reduced risk of diabetic nephropathy in patients with type 1 diabetes mellitus.
PubMedID- 19563389 Telomere length and progression of diabetic nephropathy in patients with type 1 diabetes.
PubMedID- 26239688 Microalbuminuria provides the earliest clinical marker of diabetic nephropathy among patients with type 1 diabetes, yet it lacks sensitivity and specificity for early histological manifestations of disease.
PubMedID- 20437026 The relationship of retinal vessel diameter to changes in diabetic nephropathy structural variables in patients with type 1 diabetes.
PubMedID- 25871838 Differential gene expression in diabetic nephropathy in individuals with type 1 diabetes.
PubMedID- 22643932 It is, however, not known whether such snps also confer susceptibility to diabetic nephropathy in patients with type 1 diabetes mellitus.
PubMedID- 22819809 Introduction: persistent microalbuminuria is the accepted marker for early detection of a high risk of developing diabetic nephropathy in patients diagnosed with type i diabetes mellitus.
PubMedID- 24587794 In summary, our results show that the pparγ2 polymorphism is unlikely to be associated with the development and progression of the diabetic nephropathy in patients with type 1 diabetes.
PubMedID- 21321840 Change in the amount of body fat and il-6 levels is related to altered insulin sensitivity in type 1 diabetes patients with or without diabetic nephropathy.
PubMedID- 21307382 This study is part of the ongoing finndiane study, with the aim to identify genetic, clinical, and environmental risk factors for diabetic nephropathy in patients with type 1 diabetes (7,9).
PubMedID- 26212019 Objective: the aim of this study was to investigate serum levels of mannose-binding lectin (mbl) in type 1 diabetes with diabetic nephropathy (dn) and persistent normoalbuminuria (pn).
PubMedID- 22811694 Specifically, in patients with diabetic nephropathy associated with type 1 diabetes, nisoldipine (long-acting dihydropyridine ccb) attenuates the rate of decline in glomerular filtration .
PubMedID- 20467478 The frequency of minor allele (maf) a was 0.414 in the studied population, and no significant difference of the mafs between type 1 diabetes patients with and without diabetic nephropathy was found (0.411 vs. 0.416, p-values were 0.796, test with additive model, and 0.415, test for allele positivity, respectively).
PubMedID- 23687360 Renal lesions predict progression of diabetic nephropathy in type 1 diabetes.
PubMedID- 20188385 Conversely, levels are elevated in type 1 diabetes mellitus (t1dm) and associated with microalbuminuria and diabetic nephropathy.
PubMedID- 22608880 Associations of sod1 gene variants with diabetic nephropathy were reported in patients with type 1 diabetes.
PubMedID- 24172700 Severe diabetic nephropathy in type 1 diabetes and pregnancy--a case series.
PubMedID- 22486725 Aims: the metabolic syndrome is a frequent phenomenon in people with type 1 diabetes and is associated with diabetic nephropathy.
PubMedID- 21180245 Further studies are necessary in order to demonstrate or exclude the role of cat gene in diabetic nephropathy in patients with type 1 diabetes.
PubMedID- 19395281 Endoglin expression levels and diabetic nephropathy risk in patients with type 1 diabetes.
PubMedID- 26167956 Genome-wide pathway analysis for diabetic nephropathy in type 1 diabetes.
PubMedID- 24688725 To this end the summit consortium has assembled and phenotyped the largest genome-wide association study (gwas) database for type 1 diabetes patients with diabetic nephropathy (dn).
PubMedID- 25767718 Objective: this study explored the annual occurrence/incidence of bacterial infections, and their association with chronic hyperglycemia and diabetic nephropathy, in patients with type 1 diabetes.
PubMedID- 24667182 Therefore, pemt inhibitors may be useful in the treatment of diabetic nephropathy in patients with type 1 diabetes, as well as for other er stress- and oxidative stress-related diseases.
PubMedID- 21747824 Abnormal excretion of protein is a clinically relevant indicator of impending diabetes-related renal damage; however, mechanisms underlying proteinuria in diabetic nephropathy associated with type 1 diabetes mellitus (t1d) are not completely understood.
PubMedID- 21270197 High serum lps activity also associates with the development of diabetic nephropathy in patients with type 1 diabetes (10).
PubMedID- 25575985 Methods: the most recent childbirth of 108 consecutive type 1 diabetes patients with diabetic nephropathy and a singleton pregnancy were studied.
PubMedID- 20460425 To determine whether the genetic variations identified through the gwass on european americans with type 1 diabetes are associated with susceptibility to diabetic nephropathy in japanese individuals with type 2 diabetes, we studied the association between the snps in the above four loci and diabetic nephropathy in japanese subjects with type 2 diabetes.
PubMedID- 24658196 Haptoglobin genotype and risk of diabetic nephropathy in patients with type 1 diabetes mellitus: a study on a spanish population.
PubMedID- 25032099 Although diabetic nephropathy due to type 1 diabetes mellitus (t1dm) has been studied more extensively, the vast majority of the diabetic ckd patients suffer from type 2 diabetes mellitus (t2dm).
PubMedID- 21330642 Pulse pressure predicts incident cardiovascular disease but not diabetic nephropathy in patients with type 1 diabetes (the finndiane study).
PubMedID- 23346076 Obviously, the heterozygous index is high compared to the percentage of homozygous and increased from the group of non-diabetic control subjects, to type 1 diabetes (t1d) patients without diabetic nephropathy and the patients with diabetic nephropathy.
PubMedID- 23681557 We hypothesised that variations in the cd2ap gene may contribute to susceptibility to glomerular injury in diabetes and investigated if single-nucleotide polymorphisms (snps) in cd2ap are associated with diabetic nephropathy in patients with type 1 diabetes.
PubMedID- 26339138 A very recent publication reports a close association between ficolin and diabetic nephropathy in patients with type 1 diabetes .
PubMedID- 23340892 A recent study suggested that visit-to-visit variability in blood pressure was associated with the development of diabetic nephropathy in patients with type 1 diabetes (9).
PubMedID- 25109108 Association of renin-angiotensin system genes polymorphism with progression of diabetic nephropathy in patients with type 1 diabetes mellitus.
PubMedID- 23543049 Conclusion: the association of snp loci derived from gwas in european type 1 diabetes with diabetic nephropathy was not replicated in the japanese patients with type 2 diabetes, although the erbb4 locus may have some effect also in japanese type 2 diabetes.

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