PedAM

Pediatric Disease Annotations & Medicines

Disease	dementia
Symptom	C1839611\|n syndrome
Sentences	23
PubMedID- 21739598	There is a paucity of treatment trials for dementia in down syndrome in comparison to alzheimer disease in the general (non-down syndrome) population.
PubMedID- 22888254	Down syndrome patients with dementia also show loss of memory, cognitive decline, changes in adaptive behavior, neurological changes, and language difficulties;25,26 these symptoms are progressive (not reversible).27 in contrast, the clinical features of individuals with acute neuropsychiatric disorders appear to be more similar to those of individuals with psychiatric illnesses, such as major depressive and obsessive-compulsive disorder or schizophrenia (table 1).
PubMedID- 22611513	These authors emphasize three facts: the difficulty of a differential diagnosis between psychotic symptomatology and the onset of early dementia in down syndrome patients, the role of cd in psychiatric symptoms appearance, and the improvement of psychotic symptoms with a gluten-free diet.
PubMedID- 23601808	Evidence that picalm affects age at onset of alzheimer's dementia in down syndrome.
PubMedID- 25551263	Variability of the aging process in dementia-free adults with down syndrome.
PubMedID- 26483832	Cognitive rehabilitation of dementia in adults with down syndrome: a review of non-pharmacological interventions.
PubMedID- 23902161	A prospective 14-year longitudinal follow-up of dementia in persons with down syndrome.
PubMedID- 26288825	These findings suggest a protective role of mtrnr2l12 in the development of early alzheimer's disease-like dementia in adults with down syndrome.
PubMedID- 26343344	Behavioural and psychological symptoms of dementia in down syndrome: early indicators of clinical alzheimer's disease.
PubMedID- 24885175	Interestingly, down syndrome patients with ad dementia also have an increase in mtdna mutations9.
PubMedID- 25594074	Is apolipoprotein e4 an important risk factor for dementia in persons with down syndrome.
PubMedID- 24406638	Recent research has tended to focus on dementia in down syndrome.
PubMedID- 21542885	An important limitation in scientific endeavour is the difficulty of clinical assessment of dementia in individuals with down syndrome compared with the general population.
PubMedID- 20367747	Background: the latter stages of dementia in individuals with down syndrome are well documented; however, earlier cognitive and behavioural changes have only recently been described.
PubMedID- 22763204	Seronegative sneddon syndrome, complicated with dementia, was diagnosed in each case by noticing an association between, on mri, an atrophy and several ischemic cerebrovascular accident aftermaths, and a livedo racemosa.
PubMedID- 25720405	Mtrnr2l12: a candidate blood marker of early alzheimer's disease-like dementia in adults with down syndrome.
PubMedID- 19760624	The commonest diagnoses were depression (20.2%), anxiety (5.6%), hypochondriasis (4.4%), and organic brain syndrome with or without dementia (3.6%).
PubMedID- 25363568	The presentation of dementia in down syndrome differs compared with typical alzheimer's disease.
PubMedID- 25735452	Down syndrome (ds) patients with early-onset dementia share similar neurodegenerative features with alzheimer's disease (ad).
PubMedID- 20597723	Improvements in understanding the progression of dementia in individuals with down syndrome may lead to improved diagnosis and treatment.
PubMedID- 21041786	Change in plasma ass peptides and onset of dementia in adults with down syndrome.
PubMedID- 23400708	Apoe4 is a major genetic risk factor for alzheimer disease and is associated with dementia in down syndrome and poor neurological outcome after traumatic brain injury, cerebral hemorrhage, and other neuropathological disorders.
PubMedID- 23662834	Purpose: to investigate the frequency of alzheimer-related dementia in patients with pseudoexfoliation syndrome (pex).

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