PedAM

Pediatric Disease Annotations & Medicines

Disease	dementia
Symptom	C0524851\|neurodegenerative disease
Sentences	19
PubMedID- 23986673	Ftld is the second most frequent neurodegenerative disease leading to early onset dementia after alzheimer's disease (ad).
PubMedID- 23001356	Second, approximately 20% of mci patients, who progress to dementia, are diagnosed with neurodegenerative diseases other than ad, such as vascular, lewy body, huntington, parkinson, and other dementias .
PubMedID- 23383391	The recent discovery that mutations in the gene encoding for progranulin (grn) cause frontotemporal lobar degeneration (ftld), and other neurodegenerative diseases leading to dementia, has brought renewed interest in progranulin and its functions in the central nervous system.
PubMedID- 24073234	Alzheimer’s and parkinson’s disease pd are the two most common neurodegenerative diseases of the elderly, while dementia with lewy bodies dlb is the second-most common form of dementia after alzheimer’s disease ad.
PubMedID- 21087763	Loss-of-function mutations in the progranulin gene (grn) cause frontotemporal lobar degeneration (ftld), a progressive neurodegenerative disease affecting approximately 10% of early-onset dementia patients.
PubMedID- 21645364	Loss of function mutations of the pgrn gene have been also reported to cause frontotemporal lobar degeneration (ftld), a neurodegenerative disease leading to dementia generally in the presenium.
PubMedID- 24018267	The discovery that mutations in the gene encoding for progranulin (grn) cause frontotemporal lobar degeneration (ftld) and other neurodegenerative diseases leading to dementia has brought renewed interest in progranulin and its functions in the central nervous system.
PubMedID- 22242180	Alzheimer's disease (ad) is the most frequent form of neurodegenerative disease associated with dementia in the elderly.
PubMedID- 22498202	Alzheimer's disease (ad) is a clinico-pathological diagnosis in which progressive neurodegenerative disease is associated with the dementia syndrome.
PubMedID- 24171818	Alzheimer’s disease (ad) is the most prevalent neurodegenerative disease and cause of dementia in the older population.
PubMedID- 24086754	Tauopathies, a heterogenous group of neurodegenerative diseases accompanied with dementia, are characterized by inclusions of the microtubule-binding protein tau.
PubMedID- 24561250	Alzheimer's disease (ad) is a chronic, progressive and irreversible neurodegenerative disease with clinical characteristics of memory loss, dementia and cognitive impairment.
PubMedID- 23049978	Cerebral aging is associated with the occurrence of neurodegenerative diseases leading to dementia such as alzheimer's disease (ad).
PubMedID- 21253592	Alzheimer's disease (ad) is the most common form of neurodegenerative disease with dementia in the elderly, affecting approximately 6–8% all persons aged >65 years 1.
PubMedID- 20352044	Background: amyotrophic lateral sclerosis (als), a common late-onset neurodegenerative disease, is associated with fronto-temporal dementia (ftd) in 3-10% of patients.
PubMedID- 24565007	Alzheimer's disease (ad) is a chronic neurodegenerative disease leading to cognitive decline, dementia, and ultimately death.
PubMedID- 25961991	Five (single amino acid) ns mutations are associated with severe neurodegenerative disease in man, leading to early onset dementia, epilepsy and neuronal death.
PubMedID- 25959573	Alzheimer’s disease (ad) is the most prevalent neurodegenerative disease associated with dementia, with more than 26 million cases worldwide in 2006 and an expected 106 million cases by 20501. little is known about the etiology of ad and the identification of a cure has remained elusive.
PubMedID- 20158567	Alzheimer’s disease (ad) is a neurodegenerative disease leading to dementia that affects approximately 29 million people around the world 1.

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