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PedAM

Pediatric Disease Annotations & Medicines




Disease dementia
Symptom C0085631|agitation
Sentences 44
PubMedID- 25452601 Background: agitation in dementia is common, persistent and distressing and can lead to care breakdown.
PubMedID- 22992546 Treatment of agitation and psychosis in patients with dementia remains a challenge.
PubMedID- 21954480 Context: atypical antipsychotic medications are commonly used for off-label conditions such as agitation in dementia, anxiety, and obsessive-compulsive disorder.
PubMedID- 24416196 Conversely, the use of antipsychotics against agitation in patients with dementia seems to increase all-cause mortality by 20–60% .
PubMedID- 26310190 In several countries, brexpiprazole is in development for mdds, schizophrenia, post-traumatic stress disorder and agitation in patients with dementia of the alzheimer's type.
PubMedID- 22151240 Background: agitation in dementia seriously affects not only patients' quality of life (qol), but also caregivers' qol.
PubMedID- 26303700 Objective: to assess potential genetic influences on citalopram treatment efficacy for agitation in individuals with alzheimer dementia (ad).
PubMedID- 26159445 Although further research is needed to fully determine the safety, tolerability and efficacy of these treatments, the mission to finding effective treatments for nps such as agitation in patients with dementia is well underway.
PubMedID- 22892657 agitation and psychosis associated with dementia with lewy bodies exacerbated by modafinil use.
PubMedID- 25880034 Aromatherapy has been widely applied to treat agitation in dementia patients.
PubMedID- 21982157 Fairly good evidence existed for agitation in dementia compared to control, although generalisability was limited by small sample size, lack of control and high attrition.
PubMedID- 26090227 Response rates ranged from 50% to 80% with olanzapine 2.5 mg to 10 mg. conversely, meehan and colleagues reported that olanzapine im 2.5 mg and 5 mg were superior to placebo and offered similar efficacy as lorazepam im 1 mg in alleviating acute agitation in patients with dementia .
PubMedID- 23174135 Methods: a survey of actual practice for agitation in persons with dementia was administered to 67 physicians aged 31-70+ working in nursing homes in israel.
PubMedID- 19875431 Also, a study showed that acupressure decreases agitation behavior in patients with dementia (18).
PubMedID- 23641784 The guidelines, reviews and rcts found prescription of sertraline, citalopram and trazodone to be potentially beneficial in treating behavioural perturbations, mood disorders and agitation in patients with dementia, though no level of evidence was available .
PubMedID- 22613048 The potential of volunteers to implement non-pharmacological interventions to reduce agitation associated with dementia in nursing home residents.
PubMedID- 24278880 Acupressure is recommended as an efficacious and non-intrusive method for decreasing the agitation behaviors in patients with dementia (yang et al., 2007).
PubMedID- 26307245 Background: well-being and various forms of agitation in people with dementia can be improved in a person-centered long-term care setting.
PubMedID- 21220793 Trazodone was further found to be clinically useful in generalized anxiety disorder, agitation of patients with dementia and organic disorders, chronic pain disorders, alcohol and benzodiazepine dependence.
PubMedID- 24552165 Interventions that involved changing the social environment through increasing staff knowledge and awareness, levels of supervision and reducing agitation in patients with dementia through improving psychosocial care or using aromatherapy looked promising for this patient group.
PubMedID- 25804179 agitation is commonly associated with dementia and delirium.
PubMedID- 21559196 The prevalence of agitation in dementia ranges from 20% to 60%, depending on diagnostic definitions used and the population studied .
PubMedID- 26062126 Although the general advice is to discontinue aps after 12 weeks in agitation orpsychosis associated with dementia, there may be room for prolonged treatment in somespecific circumstances.
PubMedID- 23752253 Background: impaired emotion recognition in dementia is associated with increased patient agitation, behavior management difficulties, and caregiver burden.
PubMedID- 26461064 The presence or absence of each possible adr and whether it was addressed were noted as binary variables (s1 appendix).the nature of specific benefits of the intervention, including: actions taken to reduce adrs listed on the profile (s1 appendix), such as monitoring vital signs, intake and medicines’ administration, and pain management, based on previous work pain is particularly important, as effective pain management improves the treatment of behavioural difficulties and agitation in people with dementia in care homes.
PubMedID- 23687507 The most common neuropsychiatric symptoms were agitation in patients with dementia (36.9%) and depression in those without dementia (35.6%).
PubMedID- 23293522 The primary outcomes were severity of agitation in dementia, as measured using the agitated behavior in dementia scale (abid) and the cohen-mansfield agitation inventory (cmai).
PubMedID- 24947468 There is a need for further work on interventions for agitation in people with dementia living in their own homes.
PubMedID- 20579167 Conclusion: providing stimuli offers a proactive approach to preventing agitation in persons with dementia, with live social stimuli being the most successful.
PubMedID- 24838521 Conclusions: electroconvulsive therapy may be a safe treatment option to reduce symptoms of agitation and aggression in patients with dementia whose behaviors are refractory to medication management.
PubMedID- 21327169 Akathisia due to neuroleptics may be mistaken for increased agitation in a patient with dementia and behaviour disturbance, which the clinician may erroneously respond to by raising, rather than lowering, the dose.
PubMedID- 24219098 Background: lavender essential oil shows evidence of sedative properties in neurophysiological and animal studies but clinical trials of its effectiveness as a treatment of agitation in people with dementia have shown mixed results.
PubMedID- 24715864 As seen above, very often agitation in people with dementia-related disorders is caused by the desire to overcome passitivity (yu et al., 2006).
PubMedID- 25962476 agitation in dementia and the role of spatial and sensory interventions: experiences of professional and family caregivers.
PubMedID- 23431041 The cmai involves measurement of agitation in patients with dementia and consists of 29 items rated 0–7 (0 = none and 7 = several times an hour), with a total score ranging 0 from 203. the npi was developed to assess behavioral disturbance occurring in patients with dementia.
PubMedID- 24059840 More severe dementia was associated with more severe agitation, psychosis, and apathy, but not more severe affective symptoms.
PubMedID- 25856810 Additional clinical trials include studies of brexpiprazole in attention-deficit/hyperactivity disorder and posttraumatic stress disorder, and for agitation associated with dementia of the alzheimer's type.
PubMedID- 23605454 For example, dietary restriction may cause weight loss, frequent finger sticks and insulin injections may lead to agitation especially in patients with dementia, and polypharmacy increasing risk of falls.
PubMedID- 23837414 which found a postive effect of agitation on people with dementia who had received five minutes of hand massage twice a day for 10 days: each hand was massaged for 2.5 minutes.
PubMedID- 24092982 Anxiety, irritability, and agitation in patients with dementia can be relieved with environmental modifications (avoidance of dark and noisy environments), recreation, and music and light therapies.
PubMedID- 24818033 Memantine has shown to improve agitation and delusions in patients with alzheimer's dementia .
PubMedID- 25667608 Furthermore, a beneficial effect for the management of agitation in dementia may exist, but the size of the effect appears to be modest.
PubMedID- 22685638 Thus, the onset of agitation in dementia, after use of antidepressants, should assume the investigation of a bipolar spectrum disorder.
PubMedID- 23621805 The aim of this study was to examine the effect of individual music therapy on agitation in persons with moderate/severe dementia living in nursing homes, and to explore its effect on psychotropic medication and quality of life.

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