PedAM
Pediatric Disease Annotations & Medicines
| Disease | dementia |
| Symptom | C0030567|parkinson\'s disease |
| Sentences | 71 |
| PubMedID- 21237647 | Neuropsychiatric features in parkinson's disease (pd) are associated with developing dementia longitudinally. |
| PubMedID- 26117435 | Caregiver report of apathy predicts dementia in parkinson's disease. |
| PubMedID- 26347604 | It is very difficult to distinguish dlb from dementia-associated with parkinson's disease (pdd), which shares many underlying clinical and pathological features with dlb (narayanan et al., 2013; parker et al., 2013). |
| PubMedID- 24035650 | We conclude from our review that memantine may be an effective therapeutic option in managing ad, frontotemporal dementia, dementia with lewy bodies, parkinson's disease dementia and vascular dementia. |
| PubMedID- 24516416 | described that the hsuvs in parkinson's disease with dementia equal to 0.20. there was no description on hsuvs associated with low adl levels in stroke with dementia or vascular dementia in the previous reports. |
| PubMedID- 21915906 | parkinson's disease patients with dementia had particularly high risks of mortality. |
| PubMedID- 23741227 | Previous pathological studies showed that caa in dlb and parkinson's disease with dementia may be accentuated either in the occipital areas or generalized brain areas including the frontal lobes . |
| PubMedID- 25062696 | The neuropathological substrate of dementia in patients with parkinson's disease is still under debate, particularly in patients with insufficient alternate neuropathology for other degenerative dementias. |
| PubMedID- 22579457 | dementia in parkinson's disease (pdd) and dementia with lewy bodies (dlb) are characterized by loss of acetylcholine (ach) from cortical areas. |
| PubMedID- 25781584 | The effects of cognitive reserve and lifestyle on cognition and dementia in parkinson's disease-a longitudinal cohort study. |
| PubMedID- 22484304 | Cognitive impairment and dementia in parkinson's disease. |
| PubMedID- 21442661 | Gray matter atrophy was greater in parkinson's disease with dementia, with similar change over time in both parkinson's disease and parkinson's disease with dementia. |
| PubMedID- 26195977 | Background: the specific profile of dementia in parkinson's disease (pdd) and dementia with lewy bodies (dlb) in the earliest stages of dementia is still unclear and subject of considerable controversy. |
| PubMedID- 23111294 | As the population of many countries ages, disorders of cognition and memory-such as alzheimer's disease (ad) and dementia associated with parkinson's disease-will become a major societal burden. |
| PubMedID- 23271313 | Retinal nerve fiber layer thinning in dementia associated with parkinson's disease, dementia with lewy bodies, and alzheimer's disease. |
| PubMedID- 23298332 | Importantly, it has been detected in neurons bearing neurofibrillary tangles in alzheimer's and parkinson's disease with dementia as shown in controlled studies . |
| PubMedID- 18395939 | Objective: to investigate whether automatic auditory change detection, as measured by the mismatch negativity (mmn) event-related potential waveform, differs in dementia associated with parkinson's disease (pdd) and dementia with lewy-bodies (dlb) as compared to alzheimer's disease (ad), parkinson's disease without dementia (pd) and healthy control subjects (hc). |
| PubMedID- 26294137 | parkinson's disease (pd) with dementia and falls is improved by achei. |
| PubMedID- 23843893 | For example, in ad patients, tpso pet enabled the discovery of the relationship between aβ accumulation and microglia activation during disease process 152 and can detect an age related increase in microglia activation in normal human brains and in ad progression 153. however, based on current research, no definite conclusion can be drawn between the results of amyloid plaque imaging using 11c-pib and inflammation imaging targeting tpso 53, 154, 155. microglia activation was found to be a potential driving force in the development of parkinson's disease with dementia (pdd) and could be detected via tpso pet at the early phase in pd patients 156. in stroke, tspo pet imaging was able to find the temporal dynamics of microglia activation in patients, which was correlated with clinical outcome 157. in traumatic brain injury (tbi), the imaging of microglia via tspo was found to be present up to 17 years after tbi, indicating the possible benefit of long-term interventions for post-tbi patients 158. however, some discrepancies exist among different studies, and this might be due to the lack of standardized analysis of imaging results and certain limitations of radiotracer for pet neuroinflammation imaging, such as low binding affinity and low target-to-background ratio 159. therefore, the development of new tracers with better imaging properties and the improvement in quantitative data analysis should be of great importance for pet guided neuroinflammation imaging in the future. |
| PubMedID- 22835209 | Background: neuropsychiatric symptoms (nps) are common in patients with dementia associated with parkinson's disease (pdd). |
| PubMedID- 20619503 | Lewy bodies were restricted to the medulla in case 3, corresponding to braak stage 1. in cases 1 and 4 the morphological appearances and the topographical distribution of the lewy body type pathology were comparable to those seen in severe, end-stage parkinson's disease and cases with dementia with lewy bodies (halliday et al., 2008; mckeith et al., 2005). |
| PubMedID- 25206422 | A normal control group was not included in our study, as we compared cerebral gray matter in parkinson's disease patients with and without dementia in a broader attempt to detect abnormal brain areas that are associated with dementia. |
| PubMedID- 23133788 | parkinson's disease (pd) without dementia (pdnd) is the most common subtype of lbds, followed by pd with dementia (pdd) and dementia with lewy bodies (dlbs) . |
| PubMedID- 20942300 | The german study on the epidemiology of parkinson's disease with dementia (gepad): more than parkinson. |
| PubMedID- 26494570 | Cognitive screening in parkinson's disease: comparison of the parkinson neuropsychometric dementia assessment (panda) with 3 other short scales. |
| PubMedID- 20880750 | Neuropsychological and clinical heterogeneity of cognitive impairment and dementia in patients with parkinson's disease. |
| PubMedID- 24565367 | Cheis were recommended as a treatment option for dementia with parkinson's disease. |
| PubMedID- 22814541 | The underlying mechanisms of dementia associated with parkinson's disease are only partly known and no mechanism-based treatments are available. |
| PubMedID- 20173342 | Vascular contribution to dementia in parkinson's disease. |
| PubMedID- 20523050 | Rivastigmine in the treatment of dementia associated with parkinson's disease: effects on activities of daily living. |
| PubMedID- 24625830 | We recently found that hyposmia, one of the most typical non-motor features of pd, was a predictive feature of parkinson's disease with dementia (pdd). |
| PubMedID- 26541556 | The cross-sectional and longitudinal relationships between white matter hyperintensities and dementia in patients with parkinson's disease: a retrospective analysis of 132 patients in a single center. |
| PubMedID- 21469205 | Background: sleep disturbance may represent a risk factor for the development of dementia in parkinson's disease. |
| PubMedID- 24349393 | Background: dementia in parkinson's disease (pd) is defined as cognitive decline severe enough to affect activities of daily living function (adl). |
| PubMedID- 22862741 | Initial analysis of clinical csf samples of psp (n = 46), corticobasal syndrome (cbs; n = 22), ad (n = 11), parkinson's disease with dementia (pdd; n = 16) and 35 controls revealed selective decreases of immunoreactive 4r-tau in csf of psp and ad patients compared with controls, and lower 4r-tau levels in ad compared with pdd. |
| PubMedID- 23881776 | These include: 1) amyloid-beta and tau lesions in alzheimer's disease; 2) tau lesions in three other tauopathies including pick's disease, progressive supranuclear palsy and corticobasal degeneration; 3) alpha-synuclein inclusion ratings in four synucleinopathies including parkinson's disease, parkinson's disease with dementia, dementia with lewy bodies, and multiple system atrophy; and 4) tdp-43 lesions in two tdp-43 proteinopathies, including frontotemporal lobar degeneration associated with tdp-43 and amyotrophic lateral sclerosis. |
| PubMedID- 23955613 | Is neuroinflammation involved in the development of dementia in patients with parkinson's disease. |
| PubMedID- 24195840 | Consider parkinson's disease with dementia and alzheimer's disease dementia. |
| PubMedID- 24940065 | The diagnoses were: parkinson's disease with dementia, multiple system atrophy parkinsonian type, multiple system atrophy cerebellar type, progressive supranuclear palsy, corticobasal degeneration, lewy body dementia, and frontotemporal dementia with parkinsonism. |
| PubMedID- 21684792 | Background: diagnostic criteria and procedures for dementia in parkinson's disease (pdd) have been proposed by a movement disorders society task force (mds-tf). |
| PubMedID- 25230219 | The impact of dementia development concurrent with parkinson's disease: a new perspective. |
| PubMedID- 24565164 | The pharmacology group reported that while there have been no new cognitive enhancing pharmacological agents approved for use since the last consensus conference, the role of cholinesterase inhibitors in severe ad and dementia associated with parkinson's disease is now established. |
| PubMedID- 22219275 | Alpha-synuclein is a key molecule in the pathogenesis of synucleinopathy including dementia with lewy bodies, parkinson's disease, and multiple system atrophy. |
| PubMedID- 20522088 | The epidemiology of dementia associated with parkinson's disease. |
| PubMedID- 24356537 | Background: since patterns of cognitive dysfunction in mild parkinson's disease associated with dementia (pdd) are similar to those in mild alzheimer's disease (ad), it is difficult to accurately differentiate between these two types of dementia in their early phases using neuropsychological tests. |
| PubMedID- 23426759 | Cognitive decline and dementia are frequent in patients with parkinson's disease (pd). |
| PubMedID- 24464490 | Treatment of psychosis and dementia in parkinson's disease. |
| PubMedID- 24637121 | Serum uric acid and risk of dementia in parkinson's disease. |
| PubMedID- 23887090 | As there is little evidence that antihypertensive medications affect other dementia subtypes, patients with parkinson's disease dementia,4344 frontotemporal dementia,45 lewy body dementia,46 alcohol-related dementia, post-trauma and post-anaesthetic dementia were excluded. |
| PubMedID- 22755212 | parkinson's disease with dementia (pdd). |
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