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PedAM

Pediatric Disease Annotations & Medicines




Disease congestive heart failure
Symptom C0020625|hyponatremia
Sentences 7
PubMedID- 23109779 Conivaptan is a nonspecific arginine vasopressin receptor antagonist that has been used as therapy in adults who have hypervolemic hyponatremia due to congestive heart failure.
PubMedID- 21283124 Nonetheless, vaptans are particularly useful to treat hypervolemic hyponatremia associated with severe congestive heart failure or chronic liver failure, as the only other treatments currently available, such as fluid restriction and diuretics, are slow-acting and minimally effective.
PubMedID- 24573394 Tolvaptan is a selective, competitive vasopressin receptor 2 antagonist used to treat hyponatremia associated with congestive heart failure, cirrhosis and the syndrome of inappropriate antidiuretic hormone (siadh).
PubMedID- 23463968 Tolvaptan for the treatment of hyponatremia and hypervolemia in patients with congestive heart failure.
PubMedID- 20713340 Chronic hyponatremia due to disorders of volume regulation (congestive heart failure or cirrhosis) or to syndrome of inappropriate antidiuretic hormone release can be managed effectively with vasopressin v2 receptor antagonists, but there is no evidence that controlling the hyponatremia enhances survival associated with the underlying diseases.
PubMedID- 24259510 Satavaptan (sr121463) is a vasopressin v2 receptor antagonist that has been shown to improve hyponatremia in patients with cirrhosis, congestive heart failure, and syndrome of inappropriate antidiuresis.
PubMedID- 26239456 hyponatremia is a hallmark of congestive heart failure.

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