PedAM
Pediatric Disease Annotations & Medicines
| Disease | colitis |
| Symptom | C0009402|colorectal cancer |
| Sentences | 26 |
| PubMedID- 23435402 | Five-year mortality in colorectal cancer patients with ulcerative colitis or crohn's disease: a nationwide population-based cohort study. |
| PubMedID- 25797989 | Surveillance colonoscopy (sc) is considered important for the early detection and treatment of colorectal cancer (crc) in patients with ulcerative colitis (uc). |
| PubMedID- 26357617 | Risk factors for developing cca in psc patients include elevated serum bilirubin, chronic ulcerative colitis with colorectal cancer or dysplasia, variceal bleeding, proctocolectomy, and polymorphisms of the natural killer group 2, member d (nkg2d) gene (encoding a protein involved in nk cell activity).78, 82, 83 the duration of psc may not be a risk factor for the development of cca, which is contrary to the risk factors of neoplasia in inflammatory bowel disease.77 it is suggested that dominant strictures, defined as a common bile duct stenosis with less than 1.5 mm diameter remaining in the common bile duct or a common hepatic duct stenosis close to the bifurcation leaving less than 1.0 mm diameter of the common hepatic duct,84, 85 may serve as primary indicators of concomitant cca.86 it is very challenging to distinguish between benign strictures from psc activity and cca as they can have similar characteristics on imaging. |
| PubMedID- 23118901 | Inflammation plays a crucial role in the cancer development . |
| PubMedID- 25823771 | Objectives: this study provides an overview of the largest and longest-running colonoscopic surveillance program for colorectal cancer (crc) in patients with long-standing ulcerative colitis (uc). |
| PubMedID- 23446340 | The risk of colorectal cancer in patients with long-standing ulcerative colitis or colonic crohn's disease is increased. |
| PubMedID- 25888857 | Avoiding restorative proctocolectomy for colorectal cancer in patients with ulcerative colitis based on preoperative diagnosis involving p53 immunostaining: report of a case. |
| PubMedID- 25412264 | Nuclear factor-kappa b (nf-kappab) is an important molecule in mediating inflammatory colitis, which can lead to colorectal cancer (crc). |
| PubMedID- 25437823 | The incidence of dysplasia and colorectal cancer in patients with long-standing colitis seems to be decreasing and controversy surrounds our detection and management strategies. |
| PubMedID- 21793125 | Background: ulcerative colitis (uc) is associated with colorectal cancer. |
| PubMedID- 25834332 | Aim: to determine the incidence and risk factors for colorectal cancer (crc) in patients with ulcerative colitis from a low prevalence region for crc. |
| PubMedID- 25981516 | Psc is a premalignant condition, associated with higher rates of hepatobiliary and colorectal cancer in patients with ulcerative colitis (uc). |
| PubMedID- 22104750 | The colorectal cancer risks of ulcerative colitis and crohn's disease with comparable surface area involvement and disease duration are very similar. |
| PubMedID- 21404516 | colorectal cancer, in patients with ulcerative colitis, is detected in the resected tissue of approximately 5% of patients, according to the literature. |
| PubMedID- 25649787 | Despite a low overall risk of colorectal cancer in patients with ulcerative colitis of relatively short duration, there is evidence that malignancies may be missed in that initial window. |
| PubMedID- 21722342 | Sulfasalazine has even been postulated as chemo-prevention of colorectal cancer in patients with colitis ulcerosa 8. |
| PubMedID- 22552273 | Dysplasia and colorectal cancer in a patient with ulcerative colitis and primary sclerosing cholangitis: a case report and a short review of the literature. |
| PubMedID- 21425209 | Myeloperoxidase immunohistochemistry as a measure of disease activity in ulcerative colitis: association with ulcerative colitis-colorectal cancer, tumor necrosis factor polymorphism and runx3 methylation. |
| PubMedID- 21468069 | Whether or not 5-aminosalicylates can prevent colorectal cancer among patients with colitis remains an open question. |
| PubMedID- 25029614 | colorectal cancer associated with chronic colitis arises from dysplasia. |
| PubMedID- 23867875 | Methylated eyes absent 4 (eya4) gene promotor in non-neoplastic mucosa of ulcerative colitis patients with colorectal cancer: evidence for a field effect. |
| PubMedID- 20656250 | The incidence of colorectal cancer associated with ulcerative colitis (uc) increases with time. |
| PubMedID- 24766737 | In a metaanalysis based on 116 studies, the overall prevalence of colorectal cancer in patients with ulcerative colitis was 3.7%. |
| PubMedID- 21979184 | Increased risk of colorectal cancer and dysplasia in patients with crohn's colitis and primary sclerosing cholangitis. |
| PubMedID- 21618350 | Background: chronic ulcerative colitis (uc) is associated with an increased colorectal cancer risk which may be secondary to repetitive mucosal injury. |
| PubMedID- 21859497 | Importantly, it has been reported that the administration of 0.6% curcumin in the diet prevented the progression of colorectal cancer associated with colitis in c57bl/6 mice by inhibiting the translocation of β-catenin from adherens junction complexes to the cytoplasm and nucleus and reducing the levels of diverse proinflammatory cytokines, inducible nitric oxide synthase (inos) and cox-2 as compared to untreated mice (figure 1) . |
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