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PedAM

Pediatric Disease Annotations & Medicines




Disease chronic granulomatous disease
Symptom C0021311|infections
Sentences 15
PubMedID- 20226292 Other reports expanded the clinical spectrum of disease and improved the characterization of conditions such as warts, hypogammaglobulinemia, and myelokathexis syndrome or the occurrence of mucormycosis and serratia species infections in patients with chronic granulomatous disease.
PubMedID- 23654055 Invasive fungal infections in patients with chronic granulomatous disease.
PubMedID- 23819012 Inherited defects in nadph oxidase genes cause chronic granulomatous disease, which leads to life-threatening recurrent infections, demonstrating the importance of ros in the bactericidal activity of phagocytes.
PubMedID- 23483122 In addition, multidrug resistant g. argillacea isolates may cause disseminated infections in patients with chronic granulomatous disease who receive long-term azole therapy 7.
PubMedID- 23665904 Kox-1 plays a crucial role in host defense, which is evident from recurrent and life-threatening infections that occur in patients with chronic granulomatous disease whose phagocytes genetically lack the superoxide-producing activity .
PubMedID- 23030328 infections associated with chronic granulomatous disease: linking genetics to phenotypic expression.
PubMedID- 25537872 Editorial commentary: severe infections in patients with chronic granulomatous disease.
PubMedID- 22371289 Streptococcal infections in patients with chronic granulomatous disease: case report and review of the literature.
PubMedID- 24669841 Moreover, limited evidence suggests that recombinant ifn-γ (rifn-γ) has a beneficial effect on the outcome of fungal infections in patients with chronic granulomatous disease (cgd) , hiv , leukemia , and in patients receiving organ transplants .
PubMedID- 25900657 Also, although the extent to which mpo deficiency increases susceptibility to microbial infection is debated in the field (a substantial proportion of individuals with mpo deficiency are asymptomatic), it is clear that mpo deficiency does not lead to the severe susceptibility to infections observed in patients with chronic granulomatous disease, a disorder of the phagocyte nadph oxidase (12, 13).
PubMedID- 23108438 Streptococcal infections in patients with chronic granulomatous disease: case report and review of the literature.
PubMedID- 23340515 These two patients suffer from chronic granulomatous disease with increased microbial infections in addition to wbs.
PubMedID- 24710301 Interestingly, b. cepacia that causes onion rot can also cause life-threatening pulmonary infections in individuals with chronic granulomatous disease, or cystic fibrosis (cf) .
PubMedID- 21204900 Primary defects in oxidase activity in chronic granulomatous disease (cgd) lead to severe, life-threatening infections that demonstrate the importance of the oxygen-dependent microbicidal system in host defence.
PubMedID- 22319454 Ncf1 codes for p47phox, a critical subunit in the assembly of nadph oxidase (nox); homozygous deficiency accounts for 20% of patients with chronic granulomatous disease, a disorder associated with repeated infections due to an inability to kill bacteria.

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