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PedAM

Pediatric Disease Annotations & Medicines




Disease cholestasis
Symptom C0235378|hepatotoxicity
Sentences 4
PubMedID- 20848779 Conclusion: rfp-induced hepatotoxicity was associated with cholestasis and oxidative damage.
PubMedID- 20398791 The reduced expression of the bile salt export pump (bsep/abcb11) at the canalicular membrane is associated with cholestasis-induced hepatotoxicity due to the accumulation of bile acids in hepatocytes.
PubMedID- 21339345 These diseases can mimic other hsct complications, such as infection, hemorrhage, and hepatotoxicity with cholestasis, but gvhd and veno-occlusive disease require specific treatment.
PubMedID- 25500813 The observations on elevated bilirubin level, increase in the activities of plasma enzymes and hepatic lesions imply that daoa/oa/oda elicited hepatotoxicity associated with cholestasis in mice .

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