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PedAM

Pediatric Disease Annotations & Medicines




Disease cholestasis
Symptom C0023895|liver disease
Sentences 6
PubMedID- 23166903 Objectives: to report the clinical efficacy and safety of mars therapy for intractable pruritus in cholestasis patients with stable chronic liver disease, characterizing the impact of mars on cytokine levels and on the transcriptome in the blood compartment.
PubMedID- 20425482 New evidence exists that although liver transplantation is curative for patients with end-stage liver disease owing to cholestasis, some patients may develop recurrence of cholestasis because of the emergence of autoantibodies that disrupt canalicular function in the new graft.
PubMedID- 26006201 Background/aims: there is little data concerning the incidence of alpha-1-antitrypsin"(aat) deficiency, the most common genetic cause of liver disease, among children with neonatal cholestasis in iran.
PubMedID- 19949348 Alagille syndrome is a multisystem disorder in which progressive liver disease with persistent cholestasis and dramatic pruritus often warrant consideration for liver transplantation.
PubMedID- 19447449 Fatal acute hepatitis and cholestasis associated with liver disease.
PubMedID- 23755201 cholestasis is associated with many liver diseases, and bile duct ligation (bdl) has been used in an animal model of chronic liver injury because it duplicates the hepatocyte damage, hsc activation, and liver fibrosis observed in human liver diseases.

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