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PedAM

Pediatric Disease Annotations & Medicines




Disease cardiomyopathy
Symptom C0028754|obesity
Sentences 9
PubMedID- 23817015 Background: although obesity increases the risk of developing cardiomyopathy, the mechanisms underlying the development of this cardiomyopathy are incompletely understood.
PubMedID- 24342999 For decades, it has been known that obesity is closely associated with cardiomyopathy and hypertrophy.17–19 in recent years, chronic inflammation emerged as a potential leading cause of obesity‐associated heart diseases,7–11 but the mechanisms remain to be elucidated.
PubMedID- 23978095 The role of obesity in cardiomyopathy and nephropathy.
PubMedID- 25018087 obesity-induced cardiomyopathy may be mediated by alterations in multiple signaling cascades involved in glucose and lipid metabolism.
PubMedID- 23508767 Diabetes and obesity are both associated with lipotoxic cardiomyopathy exclusive of coronary artery disease and hypertension.
PubMedID- 23302153 cardiomyopathy in obesity is associated with left ventricular hypertrophy and diastolic dysfunction with a longer exposure to obesity associated with worse cardiac function and larger ventricular mass .
PubMedID- 24614171 Many studies have shown that mitochondrial biogenesis and function are impaired in lipotoxic cardiomyopathy associated with obesity and diabetes , and that mitochondrial dysfunction is linked to cardiac dysfunction .
PubMedID- 22465089 The cardiomyopathy seen with obesity is associated with increased interstitial fibrosis and diastolic dysfunction.
PubMedID- 23196711 obesity-related diabetes mellitus leads to lipotoxic cardiomyopathy resulting in a form of cardiac dysfunction.

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