PedAM
Pediatric Disease Annotations & Medicines
| Disease | carcinoid syndrome |
| Symptom | C0016382|flushing |
| Sentences | 7 |
| PubMedID- 23316341 | Potent analogues of somatostatin (peptide hormone consisting of 14 amino acids, found in δ cells of the pancreas as well as in hypothalamic and other gastrointestinal cells) including octreotide (sandostatin) have been developed for the treatment of acromegaly, gigantism, thyrotropinoma, diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in patients with vasoactive intestinal peptide-secreting tumors (vipomas) . |
| PubMedID- 24282616 | This generally leads to well defined and debilitating clinical syndromes such as the flushing and diarrhea of the carcinoid syndrome. |
| PubMedID- 23118529 | The classical carcinoid syndrome, with flushing, diarrhea, and right-sided valvular heart disease, is caused by secretion of serotonin from a metastatic ileal carcinoid tumor. |
| PubMedID- 23100018 | The carcinoid syndrome with cutaneous flushing, bronchospasm, abdominal pain and diarrhoea develops in approximately 10% of patients with neuroendocrine tumours. |
| PubMedID- 24741994 | Evidence of carcinoid syndrome with serotonin-related flushing, generalized edema and diarrhoea, and occasional elevation of urine 5-hydroxyindoleaceticacid are uncommon and are seen in less than 10% of cases . |
| PubMedID- 22518322 | Lung carcinoids rarely produce serotonin, but may instead secrete histamine causing an atypical carcinoid syndrome with generalized flushing, diarrhea, periorbital oedema, lacrimation and asthma. |
| PubMedID- 25685590 | The most commonly reported presenting complaint in cases of carcinoid tumors is abdominal pain, and evidence of carcinoid syndrome with serotonin-related flushing, edema, and diarrhea is seen in less than 10% of cases 9. |
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