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PedAM

Pediatric Disease Annotations & Medicines




Disease cannabis abuse
Symptom C0033975|psychoses
Sentences 1
PubMedID- 26092099 Indeed, cbd may antagonize the psychoses associated with cannabis abuse.3 other receptor sites implicated in the actions of cbd include the orphan g-protein-coupled receptor gpr55, the putative endothelial cannabinoid receptor (cbe), the transient receptor potential vanilloid 1 (trpv1) receptor, α1-adrenoceptors, µ opioid receptors and 5-ht1a receptors,4,5 a cbd/thc combination (1 : 1 ratio, sativex/nabiximols) is currently licensed internationally in more than 20 countries for the treatment of spasticity in multiple sclerosis, and an as yet unlicensed cbd alone product (epidiolex) has entered an expanded access programme in children with intractable epilepsies.

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