PedAM
Pediatric Disease Annotations & Medicines
| Disease | bronchiectasis |
| Symptom | C0021311|infections |
| Sentences | 22 |
| PubMedID- 20583220 | Lung disease in this population is thought to exhibit features of one or more of the following phenotypes: recurrent sinopulmonary infections with bronchiectasis, interstitial lung disease, and lung disease associated with neurological abnormalities. |
| PubMedID- 26188881 | Respiratory complications include acute infections, the sequelae of infection (eg, bronchiectasis), non-infectious immune-mediated manifestations (notably the development of granulomatous-lymphocytic interstitial lung disease in cvid), and an increased risk of lymphoma. |
| PubMedID- 22992442 | Like in other humoral immunodeficiencies, recurrent respiratory tract infections, potentially leading to bronchiectasis, sinus infections, and ear infections are commonly found in affected patients. |
| PubMedID- 20191398 | While strong data support the use of aerosolized antibiotics for the treatment of respiratory infections in patients with cf or bronchiectasis, only a few clinical studies have examined the role of aerosolized antibiotics in the treatment of pneumonia, including ventilator-associated pneumonia (vap) in these patients. |
| PubMedID- 26519161 | This additional characterization in turn will be vital to study the epidemiology and control of chronic infections in patients with bronchiectasis, and provide valuable insights for the identification of prospective therapeutic targets and intervention strategies. |
| PubMedID- 26019629 | It may cause infections, particularly, in patients with cystic fibrosis, bronchiectasis, neutropenia, acquired immune deficiency syndrome (aids), burns and in those with metabolic, haematologic or malignant diseases. |
| PubMedID- 25378851 | Cvid usually manifests as recurrent respiratory infections that often lead to bronchiectasis later on. |
| PubMedID- 22408675 | A 14-year-old adolescent boy, a known case of common variable immunodeficiency (cvid) – the diagnosis was based on persistent low levels of immunoglobulin g (igg), decreased cd4: cd8 t-cell ratio, and recurrent bacterial infections with bilateral bronchiectasis – was on regular monthly infusions of ivig (dose 400 mg/kg) for the past 3 years in our unit. |
| PubMedID- 23919759 | histopathologically searched for patients who died of diffuse bronchiectasis associated with chronic respiratory infections, and found destructive bo showing complete destruction of the bronchiolar wall structures and its lumen replacement with collagen fibers. |
| PubMedID- 23389235 | Loss of igm-only memory b cell subset has been correlated with an increased risk of chronic respiratory infections potentially leading to bronchiectasis , while the expansion of cd21low population was associated with autoimmune cytopenia . |
| PubMedID- 25036925 | Chronic bacterial lung infections associated with non-cystic fibrosis bronchiectasis represent a substantial and growing health-care burden. |
| PubMedID- 20180797 | The picture is similar to that seen in other forms of humoral immunodeficiency with recurrent respiratory tract infections potentially leading to bronchiectasis, sinus infections and ear infections. |
| PubMedID- 26420256 | Several studies have shown that ph values may fall in non-controlled asthma or in the context of respiratory infections in patients with bronchiectasis, copd or cystic fibrosis . |
| PubMedID- 23727036 | Objective: we wanted to identify the genetic cause of cid in 2 siblings, the products of a first-cousin marriage, who experienced recurrent bacterial and candidal infections with bronchiectasis, growth delay, and early death. |
| PubMedID- 25722615 | Background: a majority of the studies done on the western population have shown that pseudomonas aeruginosa causes many severe infections in patients with bronchiectasis as compared to other pathogens. |
| PubMedID- 20100677 | Chronic respiratory infections could also lead to bronchiectasis, which can also influence chronic airway obstruction. |
| PubMedID- 25668609 | Recurrent pulmonary infections in combination with existing bronchiectasis and hemoptysis led to hospital treatment for three of the patients. |
| PubMedID- 24421048 | Such infections are associated with bronchiectasis and high mortality rates, making them a significant public health concern. |
| PubMedID- 26544950 | P. aeruginosa also dominates chronic infections in a proportion of patients with bronchiectasis where there is an increasing association with acute exacerbations. |
| PubMedID- 26542299 | Cystic fibrosis is a mono-genetic multi-system disease; however, respiratory manifestations cause the main morbidity and mortality where chronic bacterial infections lead to bronchiectasis and ultimately respiratory failure. |
| PubMedID- 25741502 | They also recognized that persistent or recurrent lower airway infections were associated with developing bronchiectasis (24). |
| PubMedID- 24451115 | Currently there are no specific treatments available for pcd, and individuals with pcd suffer from repeated respiratory tract infections eventually leading to bronchiectasis 2, 5. our laboratories have been investigating the development of gene replacement therapy as a treatment for pcd and other respiratory diseases, including cystic fibrosis. |
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