PedAM
Pediatric Disease Annotations & Medicines
| Disease | breast cancer |
| Symptom | C0279130|cns metastases |
| Sentences | 13 |
| PubMedID- 20200040 | Contrary to trastuzumab, lapatinib has activity against cns metastases in patients with her-2+ breast cancer . |
| PubMedID- 20542996 | More recently, lapatinib plus capecitabine was evaluated in a lapatinib expanded access program (leap) and a french authorisation temporaire d'utilisation (atu) program for erbb2+ breast cancer patients with cns metastases (58). |
| PubMedID- 20345334 | Nevertheless, new treatment choices have emerged considering cytotoxic and biological agents for the treatment of cns metastases in patients with breast cancer. |
| PubMedID- 23740934 | cns metastases among women with breast cancer tend to occur among those who are younger, have larger tumors, and have a more aggressive histological subtype such as the triple negative and her2-positive subtypes. |
| PubMedID- 21253507 | Historically, the incidence of clinically appearing cns metastases in patients with breast cancer is 10–20%. |
| PubMedID- 23718256 | These median survival times were much longer than that predicted by the rtog rpa and suggest that patients with cns metastases due to breast cancer survive longer than patients with cns metastases as a whole. |
| PubMedID- 24191208 | Based on our single case observation, capacitabine and lapatinib combination therapy seems as the best choice for breast cancer patients with only cns metastases. |
| PubMedID- 25433950 | cns metastases in breast cancer patients: prognostic implications of tumor subtype. |
| PubMedID- 21871802 | Herein, we retrospectively analyzed clinicopathologic data of 259 breast cancer patients with cns metastases to evaluate the association between breast cancer subtypes and cns metastasis. |
| PubMedID- 24298071 | cns metastases in breast cancer: old challenge, new frontiers. |
| PubMedID- 26277099 | Methods: information on 992 breast cancer patients with cns metastases (whose primary tumour was diagnosed between 2004 and 2010) was retrieved from the netherlands cancer registry (ncr). |
| PubMedID- 21987585 | This report describes this detection method and demonstrates the feasibility and significance of ctc detection in a pilot study of metastatic breast cancer patients with cns metastases. |
| PubMedID- 23115660 | Kim et al.17) reported that in 400 patients with cns metastases of breast cancer, 318 patients (79.5%) had pbm only, 52 patients (13%) had both pbm and lmc, and 30 patients (7.5%) had lmc only. |
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