PedAM
Pediatric Disease Annotations & Medicines
| Disease | breast cancer |
| Symptom | C0153676|lung metastasis |
| Sentences | 38 |
| PubMedID- 22279574 | Htpb delays lung metastasis of 4t1-luc breast cancer cell in animal models. |
| PubMedID- 22842551 | Apigenin, biologically active compound from scutellaria barbata prevented hepatocyte growth factor induced lung metastasis of breast cancer cells (25). |
| PubMedID- 22485156 | We had previously reported that blocking the cxcr4/cxcl12 interaction with a peptidic cxcr4 antagonist, tn14003, suppresses lung metastasis in models of breast cancer and head and neck cancer . |
| PubMedID- 26161361 | Moreover, ignt-2 expression was significantly correlated to the metastatic phenotype in breast tumor samples and its ectopic expression enhanced cell detachment, adhesion to endothelial cells, cell migration, and invasion in vitro and lung metastasis of breast cancer cells in vivo. |
| PubMedID- 24885802 | Hoxb9 has been shown to be overexpressed in human breast cancer and is associated with tumorigenicity, lung metastasis, and radioresistance . |
| PubMedID- 24330716 | Capnb2 restrains lung metastasis of breast cancer cells. |
| PubMedID- 25156580 | Among 17 breast cancer patients with lung metastasis, 5-year os and pfs rates were 72 and 36 %, respectively. |
| PubMedID- 21298335 | In conclusion, our results demonstrate the lack of usefulness of routine preoperative chest ct in detecting asymptomatic liver and lung metastasis in patients with early breast cancer. |
| PubMedID- 25928089 | Cafs #1 cells were derived from a lung metastasis of breast cancer and were immortalized by human telomerase reverse transcriptase (htert), as described previously . |
| PubMedID- 23851509 | Further evaluation verified that mir-30a was negatively correlated with the extent of lymph node and lung metastasis in patients with breast cancer. |
| PubMedID- 21812995 | Did not show significant change in lung metastasis of breast cancer in a transgenic mouse model . |
| PubMedID- 24205108 | (f) intense gata3 expression in a lung metastasis of a luminal breast cancer. |
| PubMedID- 24596532 | Semenza confirmed that hif (hypoxia inducible factor) and abcg2 are highly expressed in breast cancer cases with lung metastasis, and thought the hif family member had led to the cancer cells’ infinite proliferation by promoting the expression of ang (angiopoietin) 8. |
| PubMedID- 24278371 | According to the functional analysis we have observed a functional link between lung metastasis of breast cancer, infectious diseases and immune system. |
| PubMedID- 23527025 | Targeting mcp-1 may reduce lung metastasis of breast cancer cells. |
| PubMedID- 25250105 | In conclusion, serial cxr as the routine surveillance has not changed the endpoints of breast cancer patients with lung metastasis. |
| PubMedID- 22916270 | Furthermore, fucoidan exhibited potent anti-angiogenic activity and suppressed lung metastasis of breast cancer in vivo. |
| PubMedID- 20564396 | Methods: the authors consecutively enrolled 140 recurrent breast cancer patients with isolated lung metastasis from 1997 to 2007 in seoul national university hospital and retrospectively analyzed 45 patients who had <4 metastatic lesions. |
| PubMedID- 22315972 | This protein was found to promote lung metastasis formation of basal-like breast cancer cells by enhancing tgf-β/smad signaling and actin reorganization, thereby allowing efficient cell migration and invasion of metastatic breast cancer cells . |
| PubMedID- 25897341 | Together, these data suggest that pdt-dvdms is an effective method for inhibiting lung metastasis of breast cancer, possibly with a stronger effect than pf. |
| PubMedID- 23408836 | Inactivation of leukotriene b4 signaling or genetic deficiency of pparalpha in b cells blocks the generation of tbregs and thereby abrogates lung metastasis in mice with established breast cancer. |
| PubMedID- 25609695 | Tnc has been reported to be involved in lung metastasis of breast cancer (36). |
| PubMedID- 19838209 | However, it has been shown that only six genes are shared in common between the bone metastasis signature (kang et al., 2003; minn et al., 2005b) and lung metastasis signature (lms) of breast cancer cells (gupta et al., 2005; minn et al., 2005a). |
| PubMedID- 26356032 | Compared to wz811, msx-122, which was prepared in a single chemical step using a reductive amination reaction, further improved the pharmacokinetic profile.93 both wz811 and msx-122 block lung metastasis of breast cancer. |
| PubMedID- 25919570 | Moreover, mir-33b could inhibit tumor growth and the lung metastasis of breast cancer cells in vivo. |
| PubMedID- 23617883 | Moreover, it has been demonstrated that angptl4 disrupts vascular endothelial cell-cell junctions and promotes lung metastasis of breast cancer cells expressing transforming growth factor-β , while preventing metastasis of melanoma cells and also inhibiting angiogenesis . |
| PubMedID- 26273365 | A 38-year-old female patient was admitted for salvage right middle lobectomy as a result of a residual tumor that persisted after intensive treatment for advanced left breast cancer with lung metastasis. |
| PubMedID- 24130769 | Saha not only enhances radiosensitivity but also suppresses lung metastasis in breast cancer. |
| PubMedID- 21160267 | We report a case of recurrent breast cancer with solitary lung metastasis that has shown no recurrence with treatment by trastuzumab alone after partial resection of the right lung upper lobe. |
| PubMedID- 23390451 | Lymphangitic lung metastasis of breast cancer usually appears as reticular or reticulonodular interstitial markings, or interlobar septal thickening (kerley b lines) on imaging1. |
| PubMedID- 25595899 | Several mediators of pulmonary extravasation have recently been identified, which are up-regulated in the primary tumors of breast cancer patients with lung metastasis . |
| PubMedID- 21203518 | Such preventive effects against lung metastasis of breast cancer are clearly summarized in table 1. |
| PubMedID- 23812425 | In this report, we identified a novel klf8 and fak to mmp14 signaling mechanism for the invasive growth and lung metastasis of human breast cancer (figure 6). |
| PubMedID- 20565850 | Although previous studies found that mtdh could mediate lung metastasis of breast cancer, whether mtdh involves in the progression of breast precancerous lesions to cancer is still unknown. |
| PubMedID- 24891760 | Ew-7203, ew-7195, and ew-7197 inhibited smad/tgf-β signaling, cell migration, invasion, and lung metastasis of breast cancer cells in 4t1 and mda-mb-231 orthotropic xenograft mice and mmtv/cneu transgenic mice. |
| PubMedID- 24244818 | Ew- 7203, ew-7195, and ew-7197 inhibited smad/tgf-β signaling, cell migration, invasion, and lung metastasis of breast cancer cells in 4t1 and mda-mb-231 orthotropic xenograft mice and mmtv/cneu transgenic mice. |
| PubMedID- 22784575 | Recently, denardo et al found that cd4+ t cell promotes lung metastasis of breast cancer through macrophages . |
| PubMedID- 19690854 | Hu1a12 also showed significant efficacy in suppressing primary tumor growth and spontaneous metastasis in a mouse lung metastasis model of human breast cancer. |
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