PedAM
Pediatric Disease Annotations & Medicines
| Disease | breast cancer |
| Symptom | C0028754|obesity |
| Sentences | 117 |
| PubMedID- 23714455 | In this article, the authors review the evidence linking obesity with breast cancer risk and outcomes and provide an overview of lifestyle intervention studies in patients with breast cancer. |
| PubMedID- 26487401 | Multiple mechanisms are likely to account for the link between obesity and increased risk of postmenopausal breast cancer. |
| PubMedID- 24324792 | Amplified resistin expression may indicate insulin-resistant type ii diabetes and obesity are associated with aa breast cancer. |
| PubMedID- 21327461 | Overweight and obesity are associated with increased postmenopausal breast cancer risk; however, it is unclear whether losing excess weight will lower risk. |
| PubMedID- 26251693 | In this commentary, we consider the literature on igf and its binding proteins and the risk of breast cancer, along with effects of obesity, adipokines, and insulin resistance on breast cancer, and the potential for lifestyle interventions to address weight gain and physical inactivity among at-risk women. |
| PubMedID- 20351736 | Conclusion: obesity at the time of diagnosis of breast cancer is associated with more advanced stages and poorly differentiated grade of cancers. |
| PubMedID- 24155680 | Recent studies have indicated an association of obesity with breast cancer progression. |
| PubMedID- 21305540 | The objective of the current study was to investigate the association of obesity with breast cancer in a minority cohort. |
| PubMedID- 20941806 | Thus, hyperinsulinaemia may be one of the factors in the increased breast cancer risk seen with obesity and type 2 diabetes. |
| PubMedID- 24292402 | Purpose: obesity increases the risk of all-cause and breast cancer mortality. |
| PubMedID- 24913241 | The model analyzes the emergence of comorbidities (stroke, coronary obstructive disease, diabetes, and breast cancer) associated with obesity during a lifetime horizon. |
| PubMedID- 24455578 | A study from india also revealed a strong association of overweight and obesity with breast cancer in the indian population. |
| PubMedID- 23531051 | Our purpose was to determine if the associations of obesity with breast cancer-specific, all-cause, and non-breast cancer mortality differ between hispanic and non-hispanic white (nhw) women with breast cancer. |
| PubMedID- 24375928 | Pooled analysis yielded a summary risk ratio of 0.78 (95% confidence interval (ci): 0.67, 0.92) for hormone receptor-positive premenopausal breast cancer associated with obesity (body mass index (weight (kg)/height (m)(2)) >/=30 compared with <25). |
| PubMedID- 22279254 | The results of the present study revealed a strong association of overweight and obesity with breast cancer in the indian population. |
| PubMedID- 23041473 | Although the underlying mechanisms are not clearly defined, aromatase is thought to play a pivotal role in connecting obesity-associated inflammation with postmenopausal breast cancer. |
| PubMedID- 24512931 | Background: obesity has been associated with breast cancer risk in the caucasian population but the association remains unclear in the hispanics. |
| PubMedID- 22664497 | Many of the mechanisms that have been proposed to link obesity with breast cancer could be altered by ethnic factors8. |
| PubMedID- 26284118 | A long-lasting paradigm was born: obesity increases the incidence of postmenopausal breast cancer by causing persistently elevated adrenal oestrogen levels. |
| PubMedID- 24842266 | The aim of this study was to evaluate the influence of overweight and obesity in os in patients with locally advanced breast cancer (labc) treated with neoadjuvant chemotherapy. |
| PubMedID- 24214584 | Leptin is emerging as a key candidate molecule linking obesity with breast cancer. |
| PubMedID- 25880028 | obesity is positively associated with breast cancer risk in postmenopausal women . |
| PubMedID- 26424778 | Background: overweight and obesity are associated with breast cancer mortality. |
| PubMedID- 26335225 | A high-fat, high calorie diet and sedentary lifestyle in some asian countries also contributed to the rising incidence of obesity, which is associated with breast cancer . |
| PubMedID- 24458825 | A positive association of obesity with breast cancer incidence and mortality is well established. |
| PubMedID- 23505170 | Objective: obesity is associated with poorer breast cancer outcomes and losing weight postdiagnosis may improve survival. |
| PubMedID- 20196787 | There are still several other explanations as to the molecular mechanisms that physiologically link obesity with breast cancer risk. |
| PubMedID- 21311773 | Since experimental studies have demonstrated that adipocytes play a supportive role in breast growth , , , and as clinical studies have shown that obesity increases the incidence of breast cancer , 3, we will analyse the role of cath-d up-regulation in obese adipocytes with regard to cancer. |
| PubMedID- 23497298 | In this study, the major findings were as follows 1) bmi, an index of obesity, was significantly associated with female breast cancer. |
| PubMedID- 22125453 | According to this evidence, several hypotheses have been proposed to explain the association of obesity with postmenopausal breast cancer. |
| PubMedID- 22800711 | Whereas obesity is positively associated with breast cancer risk after menopause, it is inversely associated with risk before menopause . |
| PubMedID- 22826466 | Clinical correlation studies have clearly shown that obesity is associated with breast cancer risk and patient survival. |
| PubMedID- 24693452 | Most studies report that obesity is correlated with breast cancer in postmenopausal women; however, study from population-based sample of 1,360 australian women with breast cancer indicated that obesity is independently associated with poorer outcomes in premenopausal women, as it is in postmenopausal women . |
| PubMedID- 19929892 | obesity increases the risk of postmenopausal breast cancer and is associated with more advanced stage at presentation but no impact on survival. |
| PubMedID- 23615120 | Overweight, obesity and risk of premenopausal breast cancer according to ethnicity: a systematic review and dose-response meta-analysis. |
| PubMedID- 23564622 | obesity is associated with breast cancer in post-menopausal women, and breast density is a marker of breast cancer risk. |
| PubMedID- 25866757 | Together, these data demonstrate a link between ovarian sex steroids, obesity, and inflammation with postmenopausal breast cancer. |
| PubMedID- 22328885 | This observation has been confirmed in a recent prospective study which demonstrated that insulin resistance and obesity significantly influence risk of breast cancer development and progression . |
| PubMedID- 25884832 | Association of high obesity with pam50 breast cancer intrinsic subtypes and gene expression. |
| PubMedID- 21143857 | In general, adolescent obesity is inversely associated with breast cancer risk . |
| PubMedID- 24260287 | Moreover, while it is well-established that diabetes and obesity increase the risk of hormone-receptor positive breast cancer in postmenopausal women –, there is now accumulating evidence that indicates an increased risk of hormone receptor negative breast cancer in women with metabolic syndrome or obesity . |
| PubMedID- 26385214 | In contrast, an analysis of pooled data from three adjuvant trials of the eastern cooperative oncology group with anthracycline-based chemotherapies in 6885 patients revealed significantly poorer outcomes for obese patients (bmi ≥ 30) than for nonobese patients with hormone receptor-positive disease, but no negative impact of obesity on survival in patients with other breast cancer subtypes 6. |
| PubMedID- 26059936 | These controversies are reviewed and the complex biologic nature of the association of obesity with breast cancer addressed. |
| PubMedID- 22121495 | A recent study has shown that fabp4 levels could be a novel and obesity-independent prognostic factor in patients with breast cancer . |
| PubMedID- 26357645 | obesity increases the risk of breast cancer in postmenopausal women through a hormonal mechanism involving the metabolism of an androgenic precursor converted to estrogen in adipose tissue.67 while the obesity is a risk factor for increasing breast cancer, it seems to be a contradiction of breast density as being reverse correlated with bmi. |
| PubMedID- 21834963 | Because obesity is associated with breast cancer progression, it is important to determine whether dietary fat per se stimulates breast cancer progression in the absence of obesity. |
| PubMedID- 20129610 | Accuracy of body mass index to determine obesity in women with breast cancer: an observational study of taiwanese sample. |
| PubMedID- 22640376 | Given that obesity at diagnosis of breast cancer has been associated with an increased risk of recurrence and death , it is possible that the impact of lipocalin-2 level and/or combined score on dfs could only be demonstrated in the lower bmi group, with these markers being independent prognostic factors of breast cancer. |
| PubMedID- 25339024 | Relation of serum adiponectin levels and obesity with breast cancer: a japanese case-control study. |
| PubMedID- 26526858 | Regardless of race, both luminal er + pr+ and triple-negative breast cancers are associated with obesity during the postmenopausal period 3. |