PedAM
Pediatric Disease Annotations & Medicines
| Disease | bipolar i disorder |
| Symptom | C0086132|depressive symptoms |
| Sentences | 5 |
| PubMedID- 22296512 | Placebo on treatment outcomes based on baseline severity of core depressive symptoms in patients with bipolar i disorder. |
| PubMedID- 21689438 | Effects of asenapine on depressive symptoms in patients with bipolar i disorder experiencing acute manic or mixed episodes: a post hoc analysis of two 3-week clinical trials. |
| PubMedID- 25933099 | Background: in a previous study, adjunctive armodafinil 150 mg/day significantly improved depressive symptoms associated with bipolar i disorder. |
| PubMedID- 26509095 | Aripiprazole monotherapy resulted in some improvements in core depressive symptoms in patients with bipolar i disorder who had more severe depression; however, the difference in relation to the placebo group was not statistically significant 4. |
| PubMedID- 26330288 | This investigation adds to the evidence from two prior phase 3 studies of similar design, in which armodafinil 150 mg/day, adjunctive to protocol-allowed mood stabilizers, provided statistically significant improvement in at least some measures of depressive symptoms associated with bipolar i disorder (study 3071; nct01072929 and study 3072; nct01072630) (calabrese et al. |
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