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PedAM

Pediatric Disease Annotations & Medicines




Disease arteriosclerosis
Symptom C0040053|thrombus
Sentences 1
PubMedID- 23686369 The acute clinical manifestations of atherosclerosis result from plaque rupture, thrombus formation, and vessel occlusion.3 apoptotic cell death is a key feature of unstable plaques4 and is induced by a number of cellular stress pathways, including oxidative and endoplasmic reticulum (er) stress.5–7 the distribution of cell death is heterogeneous within advanced lesions, but is most prominent in the lipid‐rich necrotic core that contains a high density of macrophages.

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