PedAM
Pediatric Disease Annotations & Medicines
| Disease | adenoma |
| Symptom | C1608408|malignant transformation |
| Sentences | 16 |
| PubMedID- 22176788 | malignant transformation of colonic mucosa to adenoma and adenocarcinoma is associated with the accumulation of mutations in various oncogenes, tumour suppressor genes (tsgs) and chromosome, and microsatellite instability . |
| PubMedID- 24261907 | This could be related to the rare malignant transformation and size of the adenoma in gallbladders when compared to other gastrointestinal organs . |
| PubMedID- 22741056 | Synchronous urothelial carcinoma of the bladder and urachal adenoma with subsequent malignant transformation. |
| PubMedID- 20465538 | There was a consensus on complete excision for the treatment of carcinoma in situ (atypical pleomorphic adenoma) or psa with non-invasive malignant transformation. |
| PubMedID- 26430540 | However, malignant transformation of hepatic adenoma without β-catenin overexpression can be seen in 30–65% cases. |
| PubMedID- 26058379 | Hepatocellular adenoma with malignant transformation in male patients with non-cirrhotic livers. |
| PubMedID- PMC4593344 | Microscopic findings of hepatocellular adenoma (hca) with malignant transformation (hematoxylin-eosin staining × 100). |
| PubMedID- 22174424 | The aim of the present study was to investigate the participation of platelet-derived growth factor (pdgf)-a, pdgf-b, pdgf-ralpha, fibroblast growth factor (fgf)-2, flg and bek in pa, rpa and recurrent pleomorphic adenoma with malignant transformation (trpa). |
| PubMedID- 23835731 | In table 1, the clinical cases found to have malignant transformation of hepatic adenomas were summarized, with level of evidence provided according to the oxford centre for evidence-based medicine when applicable.4table 1clinical characteristics of cases of hepatic adenoma with malignant transformation in the current literaturestudy author and year (level of evidence)no. |
| PubMedID- 24708807 | Actually, malignant transformation of ocps-induced hepatic adenoma made estrogen as a hcc-promoting factor in early clinical trials . |
| PubMedID- 22927707 | Risk factors for malignant transformation are size of the adenoma (usually >5 cm), androgen or steroid use, male gender, and glycogen storage disease . |
| PubMedID- 26180619 | The pleomorphic adenoma with malignant transformation of the stromal component is extremely rare. |
| PubMedID- 24030813 | Pathologic examination showed tubulovillous adenoma with malignant transformation to adenocarcinoma. |
| PubMedID- 22363073 | In addition, malignant transformation of pleomorphic adenoma involved in the benign tumors of minor salivary glands are possible. |
| PubMedID- 20186297 | The malignant transformation of an adenoma is an uncommon event, and as in other organs, its evolution is related to the size of the adenoma. |
| PubMedID- 24653892 | malignant transformation of pleomorphic adenoma is logically possible, but it has never been identified in the external auditory canal. |
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