PedAM
Pediatric Disease Annotations & Medicines
| Disease | portal hypertension |
| Symptom | |cirrhosis |
| Sentences | 141 |
| PubMedID- 24851522 | Aim: cirrhosis with portal hypertension (pht) may be associated with increased small intestinal permeability (sip), predisposing to malnutrition and bacterial translocation causing septicaemia, endotoxaemia and spontaneous bacterial peritonitis. |
| PubMedID- 21904911 | In contrast, animals from group 4 (pvs + taa) showed well-developed micronodular and macronodular cirrhosis, associated with significant portal hypertension and hypersplenism. |
| PubMedID- 20562900 | Hepatic fibrosis and its endstage cirrhosis, with life-threatening complications of portal hypertension and liver failure, have become major public health problems1. |
| PubMedID- 26357616 | Liver damage can be progressive, leading to cirrhosis, complications of portal hypertension, and liver-related death, and, therefore, must be accurately identified. |
| PubMedID- 26422126 | Development of hyperdynamic circulation and response to beta-blockers in compensated cirrhosis with portal hypertension. |
| PubMedID- 24587847 | Patients with nash have the potential to develop fibrosis and cirrhosis leading to portal hypertension, liver decompensation, and hepatocellular carcinoma 4. |
| PubMedID- 23251280 | The patients all suffered from hepatic cirrhosis decompensation with portal hypertension. |
| PubMedID- 21213113 | Background: in patients with cirrhosis the onset of clinically significant portal hypertension (csph; i.e., hepatic venous pressure gradient (hvpg) >/= 10 mmhg) is associated with an increased risk of complications. |
| PubMedID- 21103219 | Psc is characterized by progressive periductal obliterating fibrosis and strictures in the intrahepatic and extrahepatic bile ducts and usually follows a progressive course leading to cirrhosis with complications of portal hypertension and end-stage liver failure 1. |
| PubMedID- 20616408 | cirrhosis leads to portal hypertension which induces portosystemic collaterals, allowing gut-derived humoral substances to directly enter the systemic circulation without detoxification by the liver. |
| PubMedID- 23228021 | Further investigations revealed cirrhosis with portal hypertension. |
| PubMedID- 20113491 | In addition, although splenomegaly should be expected in severe cirrhosis with portal hypertension, there were no statistical differences in splenic area among the three groups analyzed, indicating that splenomegaly was not a prominent feature in our study of cirrhotic rats. |
| PubMedID- 25848469 | This review describes the recent developments in the pathobiology of endothelial dysfunction (ed) in the context of cirrhosis with portal hypertension and defines novel strategies and potential targets for therapy. |
| PubMedID- 20425483 | Presentations range from incidentally discovered cirrhosis to complications of advanced portal hypertension and hepatocellular cancer. |
| PubMedID- 23997080 | An evaluation revealed hepatic cirrhosis with portal hypertension, secondary to chronic budd-chiari syndrome. |
| PubMedID- 21501480 | The obstruction of bile flow results in worsening cholestasis, liver fibrosis, and cirrhosis, which lead to portal hypertension and a decline in hepatic synthetic function. |
| PubMedID- 23275766 | Upper gastrointestinal hemorrhage is a common complication of hepatic cirrhosis with systemic portal hypertension, while rarely caused by pancreatic diseases. |
| PubMedID- 25374709 | In view of a normal serology, the patient's diagnosis was alcohol-related cirrhosis with portal hypertension with portal colopathy with massive lower gi bleed. |
| PubMedID- 21176011 | Although poph is most commonly observed in the setting of cirrhosis, patients with non-cirrhotic portal hypertension are also at risk of developing the disorder. |
| PubMedID- 22121492 | It is this author's opinion that 12 cm should be the threshold to diagnose splenomegaly and raise suspicion of cirrhosis with portal hypertension. |
| PubMedID- 24748895 | Meanwhile, a clinical trial demonstrated that prophylactic use of ppis did not improve the portal hypertension-related bleeding in patients with cirrhosis (41). |
| PubMedID- 25135728 | cirrhosis with portal hypertension is a common disease which has a significant impact on the quality of patients' life. |
| PubMedID- 23343370 | In our study 14 of 198 patients (7.1%) had severe cirrhosis with portal hypertension. |
| PubMedID- 21701671 | She was a known case of cryptogenic liver cirrhosis with portal hypertension. |
| PubMedID- 21843735 | Patients with recurrent complications or cirrhosis may die because of recurrent infection, portal hypertension, liver failure, or cholangiocarcinoma. |
| PubMedID- 24171010 | Table 1 summarizes the hepatobiliary clinical findings in cf.the evolution of cfld is usually slow and progressive: only about 10% of patients affected by cf and cirrhosis with portal hypertension progress to liver synthetic failure generally after pediatric age (14, 43, 44). |
| PubMedID- 22441510 | Conclusion: hscrp is elevated in patients with cirrhosis and is associated with portal hypertension and decreased survival. |
| PubMedID- 26058680 | Bacterial translocation is associated with portal hypertension in cirrhosis but this is almost unexplored in hepatosplenic schistosomiasis. |
| PubMedID- 26192141 | The management of portal hypertension in cirrhosis has evolved over time, leading to improvements in the care and survival of patients with varices and variceal hemorrhage, particularly in patients who achieve a significant reduction in portal pressure. |
| PubMedID- 21699820 | Tips has been used to manage the complications of portal hypertension in cirrhosis, including variceal hemorrhage and refractory ascites. |
| PubMedID- 24697006 | In second pregnancy, medically induced abortion was performed in the 12th week because of deterioration of the underlying disease, liver cirrhosis with portal hypertension. |
| PubMedID- 25649410 | The peripheral arterial vasodilation theory is the most widely accepted explanation for the pathophysiology of hrs (figure 1) 1, which proposes that splanchnic vasodilation that occurs as a consequence of portal hypertension with cirrhosis is the inciting factor for the development of hrs. |
| PubMedID- 25338529 | In the early stages of liver fibrosis, low ho-1 induction may exert a protective action (45), but in the end stages of cirrhosis with portal hypertension, excessive ho-1 expression deteriorates liver function and aggravates liver cirrhosis (43,46,47). |
| PubMedID- 25848466 | The treatment of cirrhosis-induced portal hypertension in children and adolescents is mostly based on methods developed for adults. |
| PubMedID- 22593813 | A minor adverse event occurred in a 56 year old man hospitalized for gastrointestinal bleeding, cirrhosis with portal hypertension, thrombocytopenia and coagulation abnormalities. |
| PubMedID- 24719556 | Background: oxidative stress is involved in the hypocontractility of visceral artery to vasoconstrictors and formation of hyperdynamic circulation in cirrhosis with portal hypertension. |
| PubMedID- 24439187 | The causes of ev included portal hypertension with cirrhosis in 52 cases (42 of hepatitis as dominant, 5 of alcoholic, 3 of biliary). |
| PubMedID- 25393320 | Complications of portal hypertension were significantly associated with cirrhosis (p<0.001) rather than with the severity of pvt and presence of cavernoma. |
| PubMedID- 24505457 | If untreated, ba progresses to cirrhosis, with portal hypertension and liver failure leading to death within two to three years. |
| PubMedID- 20951924 | This article reviews the pathophysiologic bases of the different pharmacologic treatments for portal hypertension in patients with cirrhosis and places them in the context of the natural history of varices and variceal hemorrhage. |
| PubMedID- 23293387 | Characteristically, there is worsening cholestasis, fibrosis and cirrhosis which lead to portal hypertension and a decrease in synthetic function. |