PedAM
Pediatric Disease Annotations & Medicines
| Disease | hepatitis b |
| Symptom | |infection |
| Sentences | 596 |
| PubMedID- 25830231 | Its incidence is increasing in several developed countries, particularly in asia as a result of a cohort effect related to infection with hepatitis b and c viruses 1. |
| PubMedID- 22969921 | Previous epidemiological studies have found that chronic infection with hepatitis b virus (hbv) is one of the major etiological risk factors for hcc in china. |
| PubMedID- 25795587 | The aim was to investigate the antiviral state of hdv infected human hepatocytes in the setting of co-infection with hepatitis b virus (hbv) compared to hbv mono-infection using human liver chimeric mice. |
| PubMedID- 25596623 | Additionally, risk factors such as heavy alcohol use or co-infection with hepatitis b may lead to progression of liver disease even in the presence of svr. |
| PubMedID- 25615823 | In spite of a number of well-established risk factors for liver cancer, including chronic infection with hepatitis b virus (hbv) or hepatitis c (hcv), less attention, however, has been paid to the role of dietary factors except for alcohol abuse and aflatoxin contamination in the development of this malignancy . |
| PubMedID- 25651500 | One consequence of infection with the hepatitis b virus is the development liver fibrosis, which can determine the prognosis as well as the therapy that is required (2). |
| PubMedID- 21857947 | While a higher proportion of males had abnormal liver function, suggesting possible co-infection with hepatitis b or c, this did not explain the treatment response difference. |
| PubMedID- 21791115 | An overview of triple infection with hepatitis b, c and d viruses. |
| PubMedID- 26226632 | Several risk factors have been identified to contribute to the international burden of hcc such as chronic infection with hepatitis b virus (hbv) and hepatitis c virus (hcv), alcoholic liver disease, non-alcoholic steato-hepatitis (nash), diabetes mellitus (dm), obesity, intake of aflatoxins-contaminated food, tobacco smoking, excessive alcohol drinking and genetically inherited disorders (hemochromatosis, α-1 anti-trypsin deficiency, porphyrias) 2. |
| PubMedID- 22506050 | Chronic infection with hepatitis b virus (hbv) has been recognized as a major cause of hcc . |
| PubMedID- 22095619 | After adjustment for chronic infection with hepatitis b/c viruses, family history of liver cancer was associated with hcc risk, when using both the binary indicator (or, 2.38; 95% ci, 1.01-5.58) and the fhscore, with increasing ors for successive score categories. |
| PubMedID- 22900973 | We identified two cohort studies investigating the combined and/or independent effects of infection with hepatitis b, hepatitis c and hiv. |
| PubMedID- 23626520 | Hcc usually develops in chronically damaged liver caused by an infection with the hepatitis b virus (hbv) or hepatitis c virus (hcv), alcoholic abuse and nonalcoholic fatty liver disease 2. |
| PubMedID- 25170454 | infection with hepatitis b virus (hbv) can progress to chronic liver disease, including cirrhosis and hepatocellular carcinoma (hcc), which ranks as the third cause of cancer deaths worldwide. |
| PubMedID- 23569404 | Co-infection with hepatitis b virus and/or hiv, and association with metabolic or autoimmune disorders were used as exclusion criteria in this study. |
| PubMedID- 25376591 | Results: no significant differences were observed between the two groups in terms of the clinicopathological features, which include gender ratio, liver function, accompanying cirrhosis, rate of infection with the hepatitis b virus, tumor size, tumor number, pathological type and preoperative comorbidities. |
| PubMedID- 23679074 | Despite living without immunosuppressive agents for more than 40 months, she developed a fulminant hbv infection with detection of a mutated hepatitis b virus carrying two immune escape mutations (d144e/g145r) in the hbsag (hbsie mutation). |
| PubMedID- 21569538 | infection with the hepatitis b virus (hbv) remains a very important human disease, with an estimated 400 million people infected chronically worldwide. |
| PubMedID- 22308136 | infection with hepatitis b virus (hbv) and hepatitis c virus (hcv) is a problem of worldwide significance 1. |
| PubMedID- 23065021 | For hbeag+ patients, these included previous interferon therapy, infection with hepatitis b virus (hbv) genotype a, a >/=0.5 log iu/ml decline in hbsag level within six months, and clearance of hbeag at six months. |
| PubMedID- 23007692 | The eligibility criteria were: (1) >18 years of age; (2) prior triple-drug antiretroviral regimen; (3) durability of current treatment >18 months; (4) viral load <400 copies/ml over the 18 months before evaluation and <50 copies/ml over the last 6 months; (5) cd4 count >/=250 cells/mul; (6) cd4 count nadir >100 cells/mul; (7) no previous virological failure under prior protease inhibitor-based regimen; (8) absence of co-infection with hepatitis b virus; (9) absence of hiv-related neurological disease; and (10) adherence >95 %. |
| PubMedID- 23990707 | Chronic infection with the hepatitis b virus (hbv) is associated with cirrhosis, hepatic decompensation, and hepatocellular carcinoma. |
| PubMedID- 26514586 | Chronic infection with hepatitis b virus (hbv) is accepted as a major risk factor which can lead to development of hcc 3. |
| PubMedID- 25207116 | Background: infection with hepatitis b virus (hbv) contributes to morbidity and mortality in people living with human immunodeficiency virus (hiv). |
| PubMedID- 21994866 | Chronic infection with hepatitis b and hepatitis c virus coupled with other risk factors such as diabetes, obesity, smoking, and heavy alcohol consumption contribute to this rising incidence 3. |
| PubMedID- 22857383 | Liver infection with hepatitis b virus (hbv), a dna virus of the hepadnaviridae family, leads to severe disease, such as fibrosis, cirrhosis and hepatocellular carcinoma. |
| PubMedID- 25774808 | The disease is caused by persistent infection with hepatitis b virus (hbv), and has many complex clinical manifestations . |
| PubMedID- 24812506 | The durability of viral response after achieving svr has been confirmed by many observational studies, showing that over 98% of patients who achieve svr can maintain non-viremic status after long-term post-treatment follow-up, regardless of hcv monoinfection, coinfection with hepatitis b virus (hbv) or human immunodeficiency virus (hiv), alanine aminotransferase (alt) levels, or patient ancestry.3,4 compared to the development of conventional interferon alpha (ifn α) for the treatment of chronic hcv infection, which results in only 6%–19% of svr after 24–48 weeks of treatment, the use of peginterferon alfa (peg-ifn α) in combination with ribavirin (rbv) has greatly improved the overall svr rate to 42%–52% in hcv genotypes 1/4 patients and 76%–82% in hcv genotype 2/3 patients, respectively.5–7 in addition, the introduction of response-guided therapy (rgt), where the optimized treatment duration is on the basis of early viral kinetics during the first 12 weeks of treatment, has further increased the svr rate to 70%–75%.8,9 interestingly, the svr rates of asian patients with hcv genotype 1 (hcv-1) infection receiving peg-ifn α plus rbv combination therapy are higher than those of western hcv-1 patients. |
| PubMedID- 23597411 | infection with hepatitis b and c virus in europe: a systematic review of prevalence and cost-effectiveness of screening. |
| PubMedID- 22453133 | Background: liver fibrosis in human immunodeficiency virus (hiv)-infected individuals is mostly attributable to co-infection with hepatitis b or c. |
| PubMedID- 23437062 | Chronic infection with hepatitis b virus (hbv) and hepatitis c virus (hcv), alcohol abuse, environmental and occupational toxins, as well as certain metabolic and immune disorders are risk factors of hcc . |
| PubMedID- 22325840 | Hepatocellular carcinoma (hcc), a malignancy caused mainly by chronic infection with hepatitis b virus (hbv) and/or hepatitis c virus (hcv), is a highly fatal disease. |
| PubMedID- 22359980 | The only reliable way of prevention of this infection is immunisation with hepatitis b vaccine. |
| PubMedID- 25884472 | Most cases of hcc are attributed to chronic infection with either hepatitis b or c virus 2. |
| PubMedID- 23034265 | Mechanisms associated with reactivation of hepatitis b virus (hbv) in patients with occult hbv infection (obi) remain unclear. |
| PubMedID- 22087137 | infection with hepatitis b virus and hepatitis c virus is a major risk factor for hcc in developed countries. |
| PubMedID- 22164207 | Exclusion criteria were pregnant women or women of childbearing potential, nursing mothers, male patients whose partner could have become pregnant, anaemia, leucopenia, thrombocytopenia, severe dysfunction of organs other than the liver, infection with hepatitis b virus or human immunodeficiency virus, autoimmune hepatitis, primary biliary cirrhosis, and liver dysfunction caused by drugs. |
| PubMedID- 24171011 | infection with hepatitis b virus (hbv) and hepatitis c virus (hcv) is a major risk factor for hcc in developed countries, but hcv is associated with different kinds of neoplasms such as non-hodgkin lymphomas (nhl), and with auto-immune diseases (cryoglobulinemia), which develop after the virus has caused immune system alterations (3-6). |
| PubMedID- 20607043 | The results indicate that chronic alcohol abuse was the most common risk factor (57.2%), followed by infection with hepatitis b and c viruses (hbv: 10.9% and hcv: 20.5%). |
| PubMedID- 24167653 | Hepatocellular carcinoma (hcc) is the most common form of liver cancer worldwide andchronic infection with hepatitis b virus (hbv) is one of the major causes.1 hbv infection causes chronicliver inflammation, subsequent cirrhosis, and ultimately malignant progression to hcc. |
| PubMedID- 24373091 | Hepatocellular carcinoma (hcc) is a frequent, long term complication of chronic infection with hepatitis b virus (hbv) with an annual incidence ranging from 2 to 5%, often independent from the histological stage of underlying liver disease and serological status. |
| PubMedID- 24644045 | The finding did not vary substantially by time from enrolment to diagnosis, and did not change after adjustment for biomarkers of preexisting liver damage, nor chronic infection with hepatitis b or c viruses. |
| PubMedID- 20822550 | Background: infection with hepatitis b virus (hbv) is major public health concern. |
| PubMedID- 25338920 | Chronic infection with hepatitis b virus (hbv) puts individuals at high risk for complicating cirrhosis and liver cancer, but available treatment to counter the virus rarely eliminates infection. |
| PubMedID- 23533578 | Results: vaccine efficacy against chronic infection with hepatitis b virus was 95.1% (95% confidence interval 91.5% to 97.1%), which did not vary significantly between age groups or village. |
| PubMedID- 23169288 | The predominant role of chronic infection with hepatitis b virus (hbv) and hepatitis c virus (hcv) in the aetiology of hcc is well documented (llovet et al, 2003; london and mcglynn, 2006; mueller et al, 2006). |
| PubMedID- 23028341 | Considering the high infection rate of hepatitis b virus in the general chinese population and its potential influence for complement, we furthermore carried out interaction analysis of infection-by-genotype. |
| PubMedID- 23301066 | The underlying fibrosis is often driven by chronic infection with hepatitis b virus (hbv). |
| PubMedID- 26356070 | Genotype b was more frequently detected in acute hbv infection compared with chronic hepatitis b and acute-on-chronic liver failure.44 hbv genotypes have a distinct geographical distribution.42 genotype c was dominant in the northern region of china; genotypes b and c were common in the south; genotype d was often found among ethnic minorities in tibet, xinjiang, and gansu provinces; genotype a was rare; and genotype e was only found among dai nationality in yunnan province.45 the genotype data from nine provinces showed that genotype c was predominant in the eastern (shandong and jiangsu), southern (guangdong and guangxi), northern ( jilin and beijing ), and central regions (henan and hebei) (table 1).42 in the western region (tibet,46 xinjiang,42 and qinghai47), genotype d was more common, especially in tibetans and uighurs. |
| PubMedID- 22230186 | Chronic infection with hepatitis b virus (hbv) frequently leads to serious liver disease such as cirrhosis, fulminant hepatic failure, and hepatocellular carcinoma 1. |