PedAM
Pediatric Disease Annotations & Medicines
| Disease | hepatitis b |
| Symptom | |chronic infection |
| Sentences | 209 |
| PubMedID- 26023351 | chronic infection of hepatitis b that causes drastic consequences such as liver dysfunction is viewed by clinicians and researchers as an important infectious disease. |
| PubMedID- 25666349 | chronic infections of hepatitis b (hbv) or c viruses (hcv) are both prominent risk factors in the development of hcc (bartosch et al., 2009; levrero, 2006; sun et al., 1999; wurmbach et al., 2007). |
| PubMedID- 22493738 | The major risk factors for hcc include chronic infections with the hepatitis b or c viruses, alcohol consumption, and foodstuff contamination with aflatoxins . |
| PubMedID- 22750749 | chronic infection with the hepatitis b and c virus represents a major health problem worldwide, as it is estimated that roughly 400 and 200 million people respectively, are infected by each virus. |
| PubMedID- 24316982 | The most common risk factor for developing hepatocellular carcinoma (hcc) is chronic infection with hepatitis b virus (hbv). |
| PubMedID- 24175758 | This disease tends to occur in livers damaged through alcohol abuse, or chronic infection with hepatitis b and c, on a background of cirrhosis. |
| PubMedID- 23788462 | chronic infection with hepatitis b virus (hbv) can result in progressive liver disease, hepatocellular carcinoma (hcc), and death in as many as 25% of hepatitis b surface antigen (hbsag) carriers.1 in patients with end-stage liver disease, liver transplantation (lt) is often the only treatment option. |
| PubMedID- 24159587 | The etiology of hcc is diverse; however, approximately 80% of hccs occur secondary to chronic infection with hepatitis b virus (hbv) and/or hepatitis c virus (hcv) 4. |
| PubMedID- 24779356 | chronic infection with hepatitis b virus (hbv) results in an estimated 786 000 deaths annually worldwide 1. infected individuals may remain asymptomatic for long periods but are at risk of progressive liver disease, and can transmit the virus to other susceptible individuals. |
| PubMedID- 25603021 | The etiology of hcc includes chronic infection with hepatitis b and c viruses, cirrhosis, and exposure to dietary and environmental hepatocarcinogens. |
| PubMedID- 25927412 | Major risk factors for development of hcc are chronic infection with hepatitis b virus (hbv) or hepatitis c virus (hcv), liver cirrhosis, habitual alcohol abuse, high cigarette smoking, and exposure to aflatoxin b1 . |
| PubMedID- 23906236 | A prominent factor in hepatocellular carcinoma (hcc) is chronic infection with hepatitis b virus (hbv) and hepatitis c virus (hcv). |
| PubMedID- 23533578 | Results: vaccine efficacy against chronic infection with hepatitis b virus was 95.1% (95% confidence interval 91.5% to 97.1%), which did not vary significantly between age groups or village. |
| PubMedID- 21569429 | Indeed, the main risk factors for the development of hcc among the chinese population are the presence of liver cirrhosis and chronic infection with hepatitis b virus 4. |
| PubMedID- 24644045 | The finding did not vary substantially by time from enrolment to diagnosis, and did not change after adjustment for biomarkers of preexisting liver damage, nor chronic infection with hepatitis b or c viruses. |
| PubMedID- 20107090 | chronic infection with hepatitis b virus (hbv) is an important cause of cirrhosis and cancer of the liver. |
| PubMedID- 23712427 | Demographic characteristics including age, sex, hcv risk factors, hcv genotypes, alcohol consumption, markers of chronic infection with the hepatitis b virus and hiv, hcv viral load, liver biopsy data, and hcv treatment were extracted from clinical databases. |
| PubMedID- 21605699 | For example, chronic infections with hepatitis b or hepatitis c virus are well described etiological factors for the generation of liver inflammation and hcc . |
| PubMedID- 22028694 | The incidence of hcc is increasing worldwide, mainly due to the spread of chronic infections with hepatitis b and c viruses (okuda, 2000; liovet et al., 2003; el-serag and rudolph, 2007). |
| PubMedID- 20592891 | Apart from clonorchiasis, a main risk factor of cca, the other known risk factors include chronic infection with hepatitis b and c viruses (hbv and hcv), liver cirrhosis, chronic non-alcoholic liver disease, obesity and hepatolithiasis (4, 20, 21). |
| PubMedID- 21869931 | High incidence of hcc is mostly due to the combination of two major risk factors, chronic infection with hepatitis b (hbv) and/or c (hcv) viruses and exposure to the mycotoxin aflatoxin b(1), which induces a particular mutation at codon 249 in tp53 (r249s). |
| PubMedID- 22066022 | Most hccs develop in fibrotic or already cirrhotic liver which are a result of chronic infection with hepatitis b (hbv) or hepatitis c virus (hcv) 1. |
| PubMedID- 20697376 | Worldwide, most cases of cirrhosis and liver cancer are caused by chronic infection with hepatitis b (hbv) or c viruses (hcv) (1, 2). |
| PubMedID- 23028319 | chronic infection with hepatitis b virus (hbv) can lead to liver failure and cirrhosis; it is also the leading cause of hepatocellular carcinoma. |
| PubMedID- 24594856 | chronic infection with hepatitis b virus (hbv) affects 350 to 400 million individuals worldwide and is the leading cause of liver cirrhosis and hepatocellular carcinoma worldwide 1. |
| PubMedID- 24495874 | chronic infection of the hepatitis b or c virus, together with the consequent immune response, has an important role in the carcinogenesis and development of hcc (luan et al, 2009; an et al, 2010; arzumanyan et al, 2013). |
| PubMedID- 24461059 | chronic infection with hepatitis b virus (hbv) and exposure to aflatoxin b1 (afb1) induces p53 mutations in hepatocellular carcinoma (hcc) tissue. |
| PubMedID- 23213046 | chronic infection with the human hepatitis b virus (hbv) is a global health problem and a main cause of progressive liver diseases. |
| PubMedID- 23602852 | chronic infections with hepatitis b virus (hbv) and hepatitis c virus (hcv) are highly prevalent worldwide, causing significant liver disease and thus representing high unmet medical needs. |
| PubMedID- 21143343 | chronic infection with the hepatitis b virus (hbv) is a major risk factor for development of end-stage liver disease, including cirrhosis, liver failure and primary liver cancer. |
| PubMedID- 23301066 | The underlying fibrosis is often driven by chronic infection with hepatitis b virus (hbv). |
| PubMedID- 22768213 | Although chronic infection of hepatitis b virus and hepatitis c virus are considered as the major risk factors of hcc, the etiology of hcc is still yet to be clarified 4. |
| PubMedID- 26508988 | chronic infection of hepatitis b virus (hbv) poses serious public health problems because of the high prevalence rates in many parts of the world and adverse long-term clinical outcomes, including premature deaths from hepatic decompensation, cirrhosis, and hepatocellular carcinoma 1. |
| PubMedID- 23840771 | The greatest burden of hcc is borne in sub-saharan africa and eastern asia, where chronic infection with hepatitis b virus (hbv) is highly endemic . |
| PubMedID- 25899746 | chronic infection with hepatitis b virus (hbv) plays an important role in the etiology of hepatocellular carcinoma (hcc). |
| PubMedID- 25355887 | chronic infection with hepatitis b virus (hbv) is a risk factor for developing liver diseases such as hepatocellular carcinoma (hcc). |
| PubMedID- 23299437 | chronic infection with hepatitis b virus (hbv) or hepatitis c virus (hcv) is considered the leading cause of the malignant transformation of hcc. |
| PubMedID- 24976708 | chronic infection with hepatitis b virus (hbv) constitutes a major global public health threat, causing substantial disease burdens such as liver cirrhosis and hepatocellular carcinoma, thus representing high unmet medical needs. |
| PubMedID- 23082935 | chronic infections with hepatitis b virus (hbv) and hepatitis c virus (hcv) are associated with serious health risks due to hepatic cirrhosis and hepatocellular carcinoma. |
| PubMedID- 26514586 | chronic infection with hepatitis b virus (hbv) is accepted as a major risk factor which can lead to development of hcc 3. |
| PubMedID- 25646075 | chronic infection with hepatitis b virus (hbv) is the major cause of hcc. |
| PubMedID- 23634229 | The etiological importance of chronic infection with the hepatitis b virus (hbv) and the hepatitis c virus (hcv) in hcc has been well established 3. |
| PubMedID- 21857917 | chronic infection of hepatitis b virus (hbv) is one of the major causes of liver cirrhosis and hepatocellular carcinoma (hcc) development . |
| PubMedID- 26155840 | chronic infection with hepatitis b (hbv) or hepatitis c virus (hcv) is considered the most important risk factor in hcc tumorigenesis 3. |
| PubMedID- 23098862 | chronic infection with the hepatitis b virus can lead to hepatocellular carcinoma and cirrhosis in up to 25% of infected individuals. |
| PubMedID- 25937322 | chronic infection with hepatitis b virus (hbv) occurs commonly and complications that arise from persistence of the virus are associated with high mortality. |
| PubMedID- 25072145 | chronic infection with hepatitis b virus is a cause of end-stage liver disease and hepatocellular carcinoma (hcc). |
| PubMedID- 25309066 | chronic infection with hepatitis b virus (hbv) leads to the development of hepatocellular carcinoma and/or chronic liver failure. |
| PubMedID- 26020957 | The onset and progression of hcc is related to risk factors such as chronic infection with hepatitis b and c viruses and exposure to hepatocarcinogen aflatoxin b1 1. |
| PubMedID- 24555665 | Worldwide more than 350 million subjects have chronic infection with hepatitis b virus (hbv) and around 15–20 million people are coinfected with hepatitis d virus (hdv) 1. |