PedAM
Pediatric Disease Annotations & Medicines
| Disease | hepatitis |
| Symptom | |chronic infection |
| Sentences | 332 |
| PubMedID- 21346778 | chronic infection with hepatitis b virus (hbv) is the most common cause of liver cancer worldwide, as well as a major risk factor for development of cirrhosis and end-stage liver disease.1 the hepatitis b vaccine is highly effective in preventing new infections, but ∼360 million people still suffer from chronic hepatitis b and there are ∼600 000 annual deaths from hbv-related causes.1 recent genome-wide association studies identified single nucleotide polymorphisms (snps) located within the human leukocyte antigen (hla) class ii genes hla-dpa1 and hla-dpb1 to be associated with chronic hepatitis b.2, 3 replication studies performed on two of these snps (rs3077 and rs9277535) confirmed and strengthened results from the genome-wide association studies.2 class ii hla genes encode proteins expressed on the surface of antigen-presenting cells such as macrophages, dendritic cells and b cells, and thereby have a critical role in presentation of antigens to cd4+ t-helper lymphocytes. |
| PubMedID- 23299437 | chronic infection with hepatitis b virus (hbv) or hepatitis c virus (hcv) is considered the leading cause of the malignant transformation of hcc. |
| PubMedID- 22087123 | In iran, the annual incidence of hcc is low (0.2 per 100,000, sex- and age-adjusted), possibly because of the low prevalence of chronic hbv infection (chb) .established risk factors for hcc include chronic infection with hbv and/or hepatitis c virus (hcv), old age, male sex, aflatoxin exposure, alcoholic abuse, diabetes, nonalcoholic fatty liver disease (nafld), hemochromatosis, and various host genetic factors. |
| PubMedID- 23327540 | chronic infection with hepatitis c virus (hcv) is common, but underdiagnosed and undertreated worldwide. |
| PubMedID- 22114736 | The highest hcc incidence rates are areas endemic for chronic infection with hepatitis b virus (asia and africa). |
| PubMedID- 26357610 | chronic infection with hepatitis c virus (hcv) is estimated to affect approximately 3% of the world's population and cause 350,000 deaths each year. |
| PubMedID- 21741004 | Background/purpose: chronic infection with the hepatitis c virus (hcv) is associated with impaired lipid metabolism. |
| PubMedID- 20813419 | Background & aims: chronic infection with hepatitis c virus (hcv) is often associated with elevated hepatic iron levels. |
| PubMedID- 21813371 | chronic infection with the hepatitis c virus (hcv) affects more than 3% of the world's population 1. |
| PubMedID- 24084133 | chronic infection with hepatitis b virus has a profound effect on health-related quality of life. |
| PubMedID- 25314116 | Historically, clinical trials of regimens to treat chronic infection with hepatitis c virus (hcv) have used, as their primary efficacy endpoint, a sustained virological response (svr)-defined as hcv rna levels below a designated threshold of quantification-24 weeks after the end of treatment (svr24). |
| PubMedID- 22925702 | chronic infection with hepatitis c virus (hcv) is one of the leading causes of chronic liver disease; about 170 million people worldwide are estimated to be infected. |
| PubMedID- 22947522 | chronic infection with hepatitis c virus (hcv) is a major and growing public health concern worldwide, including in latin america. |
| PubMedID- 20974315 | Background: the standard treatments for chronic infection with the hepatitis c virus (hcv) are peginterferon alpha-2a or alpha-2b plus ribavirin, but it remains unclear if one has a better efficacy and safety profile. |
| PubMedID- 20677332 | The main etiology of hcc is chronic infection with hepatitis b and hepatitis c viruses. |
| PubMedID- 26102214 | The main risk factor for hcc is chronic infection with hepatitis b or c that may lead to cirrhosis which is present in 80% to 90% of the cases of hcc . |
| PubMedID- 22807686 | Major risk factors for hcc are chronic infections with the hepatitis b or c viruses, and exposure to dietary aflatoxin b1. |
| PubMedID- 21746810 | Unlike liver cirrhosis, which, in many developing countries frequently follows chronic infection with hepatitis b or c virus, pulmonary fibrosis, and particularly idiopathic pulmonary fibrosis (ipf)—the most frequent and devastating form of the disease—typically follows noninfectious (i.e., physicochemical) tissue injury (rogliani et al., 2008). |
| PubMedID- 25899746 | chronic infection with hepatitis b virus (hbv) plays an important role in the etiology of hepatocellular carcinoma (hcc). |
| PubMedID- 24533893 | In 2009, several independent studies revealed a strong association between genetic variation in the interleukin-28b (il28b) locus and the outcome of treatment for chronic infection with hepatitis c virus (hcv). |
| PubMedID- 26035647 | chronic infection with hepatitis c virus (hcv) is characterized by liver fibrosis and cirrhosis, metabolic disorders (steatosis, insulin resistance, iron overload) and liver cancer . |
| PubMedID- 24373091 | Hepatocellular carcinoma (hcc) is a frequent, long term complication of chronic infection with hepatitis b virus (hbv) with an annual incidence ranging from 2 to 5%, often independent from the histological stage of underlying liver disease and serological status. |
| PubMedID- 22830036 | chronic infection with hepatitis c virus (hcv) is an independent risk factor for developing type 2 diabetes mellitus (dm) . |
| PubMedID- 24167653 | Hepatocellular carcinoma (hcc) is the most common form of liver cancer worldwide andchronic infection with hepatitis b virus (hbv) is one of the major causes.1 hbv infection causes chronicliver inflammation, subsequent cirrhosis, and ultimately malignant progression to hcc. |
| PubMedID- 24594856 | chronic infection with hepatitis b virus (hbv) affects 350 to 400 million individuals worldwide and is the leading cause of liver cirrhosis and hepatocellular carcinoma worldwide 1. |
| PubMedID- 25674734 | chronic infection with hepatitis b virus (hbv) often causes chronic inflammation of the liver with an increased incidence of hepatocellular carcinoma (hcc). |
| PubMedID- 22325840 | Hepatocellular carcinoma (hcc), a malignancy caused mainly by chronic infection with hepatitis b virus (hbv) and/or hepatitis c virus (hcv), is a highly fatal disease. |
| PubMedID- 22655206 | Hcc is an end result of some chronic infections with the hepatitis b (hbv) or the hepatitis c (hcv) figure 1 . |
| PubMedID- 20642483 | Sex and age differences in lipid response to chronic infection with the hepatitis c virus in the united states national health and nutrition examination surveys. |
| PubMedID- 24685721 | Background & aims: production of interferon (ifn)-gamma by natural killer (nk) cells is attenuated during chronic infection with hepatitis c virus (hcv). |
| PubMedID- 23315914 | chronic infection with the hepatitis c virus (hcv) is a leading cause of global morbidity and mortality. |
| PubMedID- 22534629 | Background: chronic infection with hepatitis c virus (hcv) is associated with failures of t-cell-mediated immune clearance and with abnormal b-cell growth and activation. |
| PubMedID- 22493738 | The major risk factors for hcc include chronic infections with the hepatitis b or c viruses, alcohol consumption, and foodstuff contamination with aflatoxins . |
| PubMedID- 23650587 | chronic infection with hepatitis c virus (hcv) is a global health problem affecting a significant proportion of world’s population. |
| PubMedID- 23712427 | Demographic characteristics including age, sex, hcv risk factors, hcv genotypes, alcohol consumption, markers of chronic infection with the hepatitis b virus and hiv, hcv viral load, liver biopsy data, and hcv treatment were extracted from clinical databases. |
| PubMedID- 23206959 | Cirrhosis of different etiologies such as alcohol, primary biliary cirrhosis, or chronic infection with hepatitis b or c (hbv, hcv) are risk factors that predispose patients to hcc2. |
| PubMedID- 26225247 | chronic infection with hepatitis c virus (hcv) affects about 170 million people worldwide and is a major cause of liver complications. |
| PubMedID- 21125320 | chronic infection with hepatitis b virus (hbv) is one of the largest racial/ethnic health disparities in the united states. |
| PubMedID- 23392071 | chronic infections with hepatitis b (hbv) and c (hcv) viruses and alcohol abuse are the major factors leading to hcc. |
| PubMedID- 23878812 | Globally, chronic infection with hepatitis b (hbv) or hepatitis c (hcv) virus is a major risk factor for hcc. |
| PubMedID- 26334902 | Approximately 75 to 80% of hcc patients are in the asia-pacific region,1 where hcc incidence is driven by the spread of chronic infection with hepatitis b and c virus (hbv/hcv), which leads to liver cirrhosis. |
| PubMedID- 19657792 | Objective: to evaluate liver function and hemostatic parameters in postmenopausal women who have chronic infection with the hepatitis c virus and climacteric symptoms and are undergoing hormone therapy (ht) (standard dose of transdermal continuous combined hormone therapy). |
| PubMedID- 26262613 | chronic infection with hepatitis c virus (hcv) can result in severe liver diseases, including cirrhosis and hepatocellular carcinoma 1. |
| PubMedID- 20546437 | chronic infection with hepatitis b virus (hbv) is a major global health problem and an important cause of morbidity and mortality from sequelae of liver cirrhosis and hepatocellular carcinoma. |
| PubMedID- 21477324 | chronic infection with hepatitis c virus (hcv) is a major and growing public health problem, which could easily lead to chronic liver disease, cirrhosis and even hepatocellular carcinoma 1. |
| PubMedID- 24644045 | The finding did not vary substantially by time from enrolment to diagnosis, and did not change after adjustment for biomarkers of preexisting liver damage, nor chronic infection with hepatitis b or c viruses. |
| PubMedID- 19902246 | chronic infection with the hepatitis c virus (hcv) represents one of the major causes for end-stage liver disease worldwide. |
| PubMedID- 21187906 | chronic infection with the hepatitis c virus (hcv) is amongst the most frequent causes of liver cirrhosis and hepatocellular carcinoma 1. |
| PubMedID- 22899946 | chronic infection with hepatitis c virus (hcv) is associated with a wide spectrum of extrahepatic manifestations, affecting different organ systems. |
| PubMedID- 23207339 | Objective: to investigate the in vivo functional roles of the la autoantigen (la), the human homologue of the 33-kda vesicle-associated membrane protein-associated protein (hvap-33), and the subunit gamma of the human eukaryotic initiation factors 2b (eif2bgamma) as co-infection factors supporting chronic infection with hepatitis c virus (hcv). |