PedAM
Pediatric Disease Annotations & Medicines
| Disease | breast cancer |
| Symptom | |obesity |
| Sentences | 117 |
| PubMedID- 26552431 | The inverse association between obesity and risk of premenopausal breast cancer is less well understood mechanistically. |
| PubMedID- 24676543 | Molecular insights into the association of obesity with breast cancer risk: relevance to xenobiotic metabolism and cpg island methylation of tumor suppressor genes. |
| PubMedID- 24829560 | The obesity-associated increased risk of post-menopausal breast cancer might be explained by higher rates of peripheral conversion of androgenic precursors to estradiol due to an increased aromatase enzyme activity in adipose tissue (48). |
| PubMedID- 25125682 | obesity is associated with a worse breast cancer prognosis and elevated levels of inflammation, including greater cyclooxygenase-2 (cox-2) expression and activity in adipose-infiltrating macrophages. |
| PubMedID- 21772329 | The increase in risk of postmenopausal breast cancer associated with obesity may be largely explained by the relatively high circulating concentrations of free oestradiol in obese postmenopausal women (endogenous hormones and breast cancer collaborative group, 2003a; rinaldi et al, 2006), but it is unclear to what extent the effects of other risk factors may be mediated by their associations with circulating sex hormones. |
| PubMedID- 26286584 | More specifically, recent studies suggest that obesity increases the incidence of breast cancer . |
| PubMedID- 21357383 | No association of risk variants for diabetes and obesity with breast cancer: the multiethnic cohort and page studies. |
| PubMedID- 23835331 | Therefore, this animal model has allowed us to determine the effects of hyperinsulinemia in isolation from many of the other factors reported to contribute to breast cancer growth with obesity, t2d, and the mets (10). |
| PubMedID- 23127511 | Our purpose is to provide a mechanistic overview of the hypothesized relationship between diet, physical activity, and obesity with breast cancer risk and progression. |
| PubMedID- 22614972 | Purpose: estrogens and androgens are elevated in obesity and associated with increased postmenopausal breast cancer risk, but the effect of weight loss on these biomarkers is unknown. |
| PubMedID- 25599228 | The local role of bat inflammation on the association of breast cancer with obesity has been recently analyzed in mice and humans , but it is still insufficiently understood and requires further examination. |
| PubMedID- 24161642 | Implications for nursing: tailored message education targeting breast cancer and risk associated with obesity is useful in breast cancer screening education. |
| PubMedID- 20540734 | obesity is associated with increased breast cancer risk in postmenopausal women . |
| PubMedID- 20670865 | Background: obesity is strongly associated with endometrial and breast cancers; further, obese women are less likely to undergo recommended cancer screening. |
| PubMedID- 23570924 | Development of overweight and obesity in breast cancer patients and its significance for diagnosis and clinical management: results of the basel breast cancer database 1990-2009. |
| PubMedID- 21467202 | Greater bmi and obesity are associated with decreased breast cancer risk in studies of premenopausal women (friedenreich, 2001; berstad et al., 2010) while both current and former oc users have an increased risk of breast cancer in recent studies (lund et al., 2007; hunter et al., 2010). |
| PubMedID- 26303657 | obesity has been associated with breast cancer recurrence and poorer survival. |