PedAM
Pediatric Disease Annotations & Medicines
| Disease | temporal lobe epilepsy |
| Symptom | |hippocampal sclerosis |
| Sentences | 142 |
| PubMedID- 22497612 | Defining clinico-neuropathological subtypes of mesial temporal lobe epilepsy with hippocampal sclerosis. |
| PubMedID- 24814212 | Our knowledge on temporal lobe epilepsy (tle) with hippocampal sclerosis has evolved towards the view that this syndrome affects widespread brain networks. |
| PubMedID- 23056977 | In most series, the most commonly identified pathologies include mesial temporal or hippocampal sclerosis (in patients with temporal lobe epilepsy), focal cortical dysplasia, tumors, and remote infarcts/ischemic damage . |
| PubMedID- 24304474 | Four patients had symptomatic focal epilepsy: two had bilateral hippocampal sclerosis with temporal lobe epilepsy; one had tuberous sclerosis, and the other had a congenital noncommunicating hydrocephalus. |
| PubMedID- 22734123 | Magnetic resonance imaging-positive temporal lobe atrophy with temporo-polar grey/white matter abnormalities (usually called 'blurring') has been frequently reported in patients with temporal lobe epilepsy associated with hippocampal sclerosis. |
| PubMedID- 25775210 | Kainic acid-induced status epilepticus (ka-se) in mature rats results in the development of spontaneous recurrent seizures and a pattern of cell death resembling hippocampal sclerosis in patients with temporal lobe epilepsy. |
| PubMedID- 20733146 | Objectives: to examine the influence of side of pathology and gender on changes in cognitive function across the adult lifespan in a homogenous sample of patients with mesial temporal lobe epilepsy (mtle) associated with unilateral hippocampal sclerosis (hs). |
| PubMedID- 19926226 | temporal lobe epilepsy with hippocampal sclerosis (tle-hs) is one of the more common forms of chronic epilepsy. |
| PubMedID- 25552301 | Unique methylation profiles were evident in temporal lobe epilepsy with or without hippocampal sclerosis, in addition to a common methylation profile regardless of pathology grade. |
| PubMedID- 26073635 | Background and purpose: medial temporal lobe epilepsy with unilateral hippocampal sclerosis (mtle-hs) is the most frequent form of surgical temporal lobe epilepsy. |
| PubMedID- 22520586 | Auras in temporal lobe epilepsy with hippocampal sclerosis: relation to seizure focus laterality and post surgical outcome. |
| PubMedID- 24567716 | Have showed that in mesial temporal lobe epilepsy (mtle) patients with hippocampal sclerosis (hs), there are reductions in functional and structural connectivity between hippocampal structures and their adjacent regions (liao et al., 2011). |
| PubMedID- 22079883 | Ah-dbs was implemented with biphasic versus pseudo monophasic charge balanced pulses, in two groups of patients: six with temporal lobe epilepsy (tle) associated with hippocampal sclerosis (hs) and six with non lesional (nles) temporal epilepsy. |
| PubMedID- 22038783 | We aimed to identify the brain areas involved in verbal and visual memory processing in normal controls and patients with unilateral mesial temporal lobe epilepsy (mtle) associated with unilateral hippocampal sclerosis (hs) by means of functional magnetic resonance imaging (fmri). |
| PubMedID- 25031702 | Using the pilocarpine model of chronic spontaneous recurrent seizures, which mimics the main features of mesial temporal lobe epilepsy (tle) with hippocampal sclerosis (hs) in humans, we examined the expression of cb1r in hippocampal astrocytes of epileptic rats. |
| PubMedID- 23140034 | Outcomes after temporal lobectomy for temporal lobe epilepsy with hippocampal sclerosis. |
| PubMedID- 24358235 | In relation to the use of vpa as an anti-epileptic drug, the finding that dicer protein is reduced in temporal lobe epilepsy (tle) with hippocampal sclerosis is most interesting . |
| PubMedID- 24492975 | A high priority is currently being placed on investigations to elucidate fundamental mechanisms of epileptogenesis and identify biomarkers for specific models of human epilepsy, such as mesial temporal lobe epilepsy with hippocampal sclerosis, traumatic brain injury, and a variety of pediatric diseases, including tuberous sclerosis and west syndrome. |
| PubMedID- 23818976 | Purpose: to investigate epilepsy-induced changes in effective connectivity between the non-epileptic amygdalo-hippocampal complex (ahc) and the rest of the brain in patients with unilateral mesiotemporal lobe epilepsy (mtle) associated with hippocampal sclerosis (hs). |
| PubMedID- 25934585 | Status epilepticus (se) is one of the recognized primary precipitating events that can lead to temporal lobe epilepsy (tle) associated with hippocampal sclerosis. |
| PubMedID- 21211543 | This study was delineated to study the distribution and the co-localization of hk1 and kinin b1 and b2 receptors with glial and/or neuronal proteins markers, in the hippocampus of patients with refractory temporal lobe epilepsy, associated with hippocampal sclerosis (tle-hs), comparing with control tissues. |
| PubMedID- 23912569 | A quadruple examination of ictal eeg patterns in mesial temporal lobe epilepsy with hippocampal sclerosis: onset, propagation, later significant pattern, and termination. |
| PubMedID- 26328621 | Perspectives on treatment options for mesial temporal lobe epilepsy with hippocampal sclerosis. |
| PubMedID- 26425829 | Objective: the hippocampus consists of several functionally and histologically different subfields that are known to be differentially affected in mesial temporal lobe epilepsy with hippocampal sclerosis (mtle). |
| PubMedID- 21810779 | First, we studied temporal lobe epilepsy (tle) patients with left hippocampal sclerosis (hs) (trenerry et al. |
| PubMedID- 23928193 | In total, we reviewed 491 seizures: 277 seizures in patients with temporal lobe epilepsy (tle) associated with hippocampal sclerosis (tle-hs group) and 214 in tle caused by other lesions (tle-oth group). |
| PubMedID- 24147214 | Mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) is a common medically intractable epilepsy syndrome. |
| PubMedID- 25849340 | Evidence suggests there are subtypes of mesial temporal lobe epilepsy (mtle) with or without hippocampal sclerosis (hs), and some of which could have less likelihood for postsurgical seizure-freedom . |
| PubMedID- 23265552 | Neurocysticercosis (ncc) and mesial temporal lobe epilepsy associated with hippocampal sclerosis (mtle-hs) are two common worldwide forms of focal epilepsy. |
| PubMedID- 24098357 | Recent data showed that loss of dicer and failure of mature mirna expression may be a feature of hippocampal sclerosis in patients with temporal lobe epilepsy . |
| PubMedID- 20547107 | Assessment of working memory in patients with mesial temporal lobe epilepsy associated with unilateral hippocampal sclerosis. |
| PubMedID- 24074891 | Mesial temporal lobe epilepsy (mtle) associated with hippocampal sclerosis (hs) is considered an electroclinical syndrome, and there is a debate whether it is a unique disease or an entity with distinct subtypes. |
| PubMedID- 25866531 | Psychiatric symptoms in temporal lobe epilepsy with left mesial hippocampal sclerosis. |
| PubMedID- 23465565 | Purpose: to investigate the prognostic value of ictal scalp eeg patterns in drug-resistant temporal lobe epilepsy associated with hippocampal sclerosis (mtle-hs) prior to undergoing temporal lobectomy. |
| PubMedID- 22510097 | Asymmetric cortical surface area and morphology changes in mesial temporal lobe epilepsy with hippocampal sclerosis. |
| PubMedID- 21444904 | Objectives: the purpose of the study was to investigate the abnormalities of cortical lamination observed in temporal lobe specimens obtained during surgery for intractable temporal lobe epilepsy (tle) with hippocampal sclerosis. |
| PubMedID- 23055516 | The largest presurgical/surgical group was mediotemporal lobe epilepsy with hippocampal sclerosis (29.5%/35.4%). |
| PubMedID- 23634661 | Our aim was to verify if the triad kl-nfkb1-tnf is also dysregulated in temporal lobe epilepsy associated with hippocampal sclerosis (tle(hs)) patients. |
| PubMedID- 24962348 | Memory impairment is not necessarily related to seizure frequency in mesial temporal lobe epilepsy with hippocampal sclerosis. |
| PubMedID- 23027102 | Purpose: medial temporal lobe epilepsy (tle) with hippocampal sclerosis has both a scalp eeg initial ictal discharge frequency, which is faster, and also an intracranial eeg onset site that is more restricted to the hippocampus, than lateral tle without hippocampal sclerosis. |
| PubMedID- 25668490 | Altered vesicular glutamate transporter expression in human temporal lobe epilepsy with hippocampal sclerosis. |
| PubMedID- 26216514 | Objective: medial temporal lobe epilepsy (tle) with hippocampal sclerosis is often accompanied by widespread changes in ipsilateral and contralateral white matter connectivity. |
| PubMedID- 23991095 | Mesial temporal lobe epilepsy (mtle) with hippocampal sclerosis is one of the most common forms of drug-resistant partial epilepsy in humans 1. |
| PubMedID- 20663517 | Mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) is a group of chronic disorders characterized by prominent neuronal loss and gliosis in the hippocampus and amygdala. |
| PubMedID- 23511251 | Enhanced sequential reaction time task performance in a rat model of mesial temporal lobe epilepsy with classic hippocampal sclerosis. |
| PubMedID- 24791093 | Surgically remediable epilepsies should be identified early and include temporal lobe epilepsy with hippocampal sclerosis, lesional temporal and extratemporal epilepsy, hemispherical epilepsy, and gelastic epilepsy with hypothalamic hamartoma. |
| PubMedID- 24406303 | Since this decrease is consistently observed in the human sclerotic ca1, this feature can be considered another key pathological indicator of hippocampal sclerosis associated with temporal lobe epilepsy. |
| PubMedID- 21789691 | Those are (1) inflammatory processes which play an increasingly important role for the generation of temporal lobe epilepsy with hippocampal sclerosis (tle with hs), (2) disturbances of intrinsic properties of neuronal compartments, in particular acquired defects of ion channels of which those in dendrites are described here for tle with hs, (3) epigenetic effects, which affect for example the methylation of promoters and secondarily can change the expression of specific genes in tle with hs, and finally (4) the epileptogenesis of idiopathic epilepsies which are caused by inborn genetic alterations affecting mainly ion channels. |
| PubMedID- 25206850 | Changes in astrocytic transporters and receptors in hippocampal sclerosis of temporal lobe epilepsy7 lead to functional changes of water channels and ion channels in reactive astrocytes, resulting in a deteriorated environment at the onset and development of epilepsy. |
| PubMedID- 23787169 | Periodic epileptiform discharges in mesial temporal lobe epilepsy with hippocampal sclerosis. |