PedAM
Pediatric Disease Annotations & Medicines
| Disease | portal hypertension |
| Symptom | |cirrhosis |
| Sentences | 141 |
| PubMedID- 24099470 | Background: the hepatic venous pressure gradient (hvpg) is an invasive, but important diagnostic and prognostic marker in cirrhosis with portal hypertension (pht). |
| PubMedID- 25013336 | Ehpvo has a unique clinical profile, which differentiates it from portal hypertension associated with cirrhosis of the liver. |
| PubMedID- 26240773 | He had uncomplicated child-pugh class a cirrhosis with no history of portal hypertension. |
| PubMedID- 20814511 | Surgical intervention in cirrhosis of liver with portal hypertension is associated with increased morbidity and mortality. |
| PubMedID- 25709491 | It has been identified as one of the leading causes of mortality, with close to 50,000 deaths attributed to it per year in the united states.1 the major morbidity from cirrhosis is due to portal hypertension, with formation of venous collaterals and marked circulatory as well as vascular abnormalities. |
| PubMedID- 26406236 | Background & aims: although in cirrhosis with portal hypertension levels of the vasoconstrictor angiotensin ii are increased, this is accompanied by increased production of angiotensin (ang)-(1-7), the endogenous ligand of the mas receptor (masr), which blunts hepatic fibrosis and decreases hepatic vascular resistance. |
| PubMedID- 23999681 | Combined biliovascular injuries, segmental atrophy, and secondary biliary cirrhosis with portal hypertension are special circumstances which are best managed by a multidisciplinary team at an experienced center for optimal outcomes. |
| PubMedID- 24940392 | In addition, cirrhosis leads to portal hypertension and hyperdynamic circulation that can have widespread effects in the body (15). |
| PubMedID- 23983486 | His medical history was significant for alcoholic cirrhosis with portal hypertension, splenomegaly, hypersplenism, and ascites. |
| PubMedID- 23670970 | Liver disease was defined by clinician diagnosis in two studies (tss and cgs), whereas the gms study required documentation of portal hypertension attributable to cirrhosis (15). |
| PubMedID- 23559324 | Olt was performed at the age of 7 years, due to liver cirrhosis with portal hypertension, in the absence of neurological lesions and an almost-normal brain mri. |
| PubMedID- 23812828 | Histopathological evaluation remains critical in excluding cirrhosis and other causes of portal hypertension, and is the only way of definitively establishing the diagnosis of opv. |
| PubMedID- 21423905 | Color doppler evaluation of left gastric vein hemodynamics in cirrhosis with portal hypertension and its correlation with esophageal varices and variceal bleed. |
| PubMedID- 24137205 | It has been suggested that splenic siderotic nodules in patients with cirrhosis may be attributed to portal hypertension. |
| PubMedID- 21116340 | Patients with cirrhosis and signs of portal hypertension (platelet count <140,000/mm3) should have screening endoscopy. |
| PubMedID- 23787475 | Oct is a somatostatin analogue that has few side effects, and its injection is clinically used for lowering the portal hypertension associated with liver cirrhosis 5. |
| PubMedID- 22334252 | Development of ascites in compensated cirrhosis with severe portal hypertension treated with beta-blockers. |
| PubMedID- 22848732 | Diagnosis of cfld is challenging because its clinical presentation ranges from simple steatosis to multi-lobular biliary cirrhosis with portal hypertension . |
| PubMedID- 21994871 | Since ascites in cirrhosis develops due to portal hypertension, it would seem logical to decompress the portal system to reduce the ascites. |
| PubMedID- 26064107 | They can detect advanced cirrhosis with signs of portal hypertension (enlarged spleen and portal vein, and collateral venous circulation), but not fibrosis of lesser stages . |
| PubMedID- 23831908 | The natural history of cirrhotic patients is highly variable due to several factors including hepatic synthetic function, presence and degree of portal hypertension, the cause of cirrhosis, the possibility of resolution of the underlying damaging process, and the occurrence of liver cancer. |
| PubMedID- 20921950 | portal hypertension in cirrhosis depends on increased intrahepatic vascular resistance, which is explained by fibrosis and intrahepatic hyperresponsiveness to vasoconstrictors. |
| PubMedID- 21705304 | A detailed interview and examination by occupational health and other medical specialists revealed that the patient had been suffering from wilson's disease from the age of 13, and had now developed hepatic manifestations (compensated liver cirrhosis with portal hypertension), neurological manifestations (dystonia, dysarthria, muscle weakness, vertigo), and psychiatric manifestations (depression, insomnia, cognitive impairment) of the disease, including problems partially caused by long-lasting treatment with copper chelating agents (neurological and haematological manifestations). |
| PubMedID- 23799952 | Simvastatin is known to be effective in resolving portal hypertension in patients with cirrhosis (46,47). |
| PubMedID- 20968204 | The kidney in cirrhosis with portal hypertension. |
| PubMedID- 21801303 | Both processes are important for the development of the hyperdynamic circulatory syndrome associated with portal hypertension in cirrhosis . |
| PubMedID- 22811587 | Hepatic manifestations were first described by klatskin and yesner in 1950 and include granulomatous hepatitis, cholestasis, cirrhosis, portal fibrosis leading to presinusoidal portal hypertension, budd-chiari syndrome, adult ductopenia-like syndrome, and rarely chronic granulomatous sclerosing cholangitis with ductal strictures . |
| PubMedID- 24274743 | The ccl4 model of liver injury is used in mice, rabbits and rats and leads to cirrhosis with portal hypertension. |
| PubMedID- 24563796 | Relevant diagnoses of the patient were (i) known hypertensive cardiac disease (transthoracic echocardiography 6 months before had shown a lv-ef of 54% and a light mitral and tricuspid insufficiency) and (ii) liver cirrhosis with portal hypertension. |
| PubMedID- 22009385 | Background: portal hypertension associated with liver cirrhosis increases the risk of postoperative complications after liver resection for hepatocellular carcinoma (hcc). |
| PubMedID- 20704762 | cirrhosis leads to portal hypertension of varying extents. |
| PubMedID- 21806953 | Background & aims: cirrhosis patients with symptomatic portal hypertension might be effectively treated with a transjugular intrahepatic portosystemic shunt stent (tips). |
| PubMedID- 22568417 | This study considers a possible role of fibrosis evaluation by transient elastography (fibroscan((r))) and its correlation with portal hypertension in patients with cirrhosis, and discusses the use of this technique in planning therapeutic options in patients with hepatocellular carcinoma (hcc). |
| PubMedID- 25457205 | Background & aims: inflammation, collagen deposition and tissue remodelling are involved in the pathogenesis and complications of cirrhosis with portal hypertension. |
| PubMedID- 25969457 | Varices are known to develop in patients having cirrhosis with portal hypertension. |
| PubMedID- 25037870 | Hcc patients seemed to suffer from less severe or shorter duration of portal hypertension compared with child-pugh class-matched cirrhosis patients. |
| PubMedID- 22558526 | He had cirrhosis and thrombocytopenia with portal hypertension, possibly secondary to alcohol use. |
| PubMedID- 23056756 | Liver involvement might progress toward the cirrhosis, accompanied with portal hypertension, ascites and esophageal varicosities, but these manifestations were otherwise mainly absent in our group. |
| PubMedID- 25263269 | Successful pregnancy is possible in well-compensated cirrhosis or with mild portal hypertension, although the maternal and foetal mortality and morbidity are higher than in the general population. |
| PubMedID- 24678881 | Clinical studies showed that the markers bgm, elastin mmp-generated neo-epitope fragment (elm) c1m, c3m, c4m c5m, collagen type vi mmp-generated neo-epitope fragment (c6m), pro-c3 and p4np 7s were associated with portal hypertension in patients with cirrhosis, reflecting the degree of liver dysfunction. |
| PubMedID- 24493093 | From 2,879 cases that underwent ce, 45 cirrhosis patients with portal hypertension (ph) were enrolled and divided into phe (n = 18) and non-phe (n = 27) groups. |
| PubMedID- 23755897 | Propranolol treatment of portal hypertension in cirrhosis patients is better the higher the untreated pressure: a single-centre prospective experience. |
| PubMedID- 23984413 | Spleen stiffness, but not liver stiffness, was positively correlated with the presence of ascites as a representative marker of portal hypertension in patients with liver cirrhosis and the spleen stiffness did not correlate with the presence of esophageal varices in chronic hepatitis c patients. |
| PubMedID- 24324910 | For a definitive diagnosis of hps, patients must meet three criteria: (1) room air po2 < 80 mmhg or a-a gradient > 15 mmhg, (2) evidence of intrapulmonary shunting (typically on contrast-enhanced echocardiography or a lung perfusion scan), and (3) portal hypertension with or without cirrhosis 1. |
| PubMedID- 21785606 | Intestinal bacterial overgrowth, seen in patients with advanced cirrhosis as a result of portal hypertension, has been noted to be a prerequisite for the facilitation of bacterial translocation. |
| PubMedID- 20583425 | Background/aims: endosonography (eus) is rarely used in the routine diagnostic of portal hypertension in patients with cirrhosis even though it has significantly higher sensitivity for detection of varices than gastroduodenoscopy. |
| PubMedID- 23729979 | Portal vein interventions in liver transplant recipients represent a group of interventions in the management of several disease entities including portal vein stenosis, portal vein thrombosis, and recurrent liver cirrhosis with portal hypertension with and without gastric varices. |
| PubMedID- 25053449 | Liver collagen in cirrhosis correlates with portal hypertension and liver dysfunction. |
| PubMedID- 25356325 | Resultant complications included compensated cirrhosis with portal hypertension, oesophageal varices and a previous episode of culture-negative sbp. |
| PubMedID- 22034603 | 1 pah is also an uncommon but documented complication of hiv infection, chronic hemolytic anemia, and cirrhosis with portal hypertension. |