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PedAM

Pediatric Disease Annotations & Medicines




Disease neutropenia
Symptom |fever
Sentences 61
PubMedID- 24064965 Molecular-based diagnosis of bacteremia in the setting of fever with or without neutropenia in pediatric hematology-oncology patients.
PubMedID- 22050689 Mbl2 and fever during neutropenia in children with acute lymphoblastic leukaemia.
PubMedID- 25931813 If an adverse event required dose interruption, the nab-paclitaxel dose was reinitiated at the start of a treatment cycle if the patient’s absolute neutrophil count was ≥ 1,500 cells/µl, the patient's platelet count was ≥ 100,000 cells/µl, and any other toxicity resolved to grade 1. patients experiencing grade 3–4 neutropenia, with or without fever, or grade 2 symptomatic anemia could receive hematological support with granulocyte colony-stimulating factor or erythropoietin.
PubMedID- 23637925 1 the management of fever with neutropenia is relatively straightforward in these children after they begin chemotherapy.
PubMedID- 25684313 Treatment had to be stopped early in eight (19%) patients, mainly due to limiting toxicity in five patients (diarrhea, febrile neutropenia, neutropenia without fever, diarrhea with febrile neutropenia, and skin toxicity), one toxic death (colonic perforation), one acute pancreatitis, and one consent withdrawal.
PubMedID- 24281308 The dlts were fever with grade 3/4 neutropenia, grade 3 fatigue and grade 3 mucositis.
PubMedID- 21285987 Dlts were defined as grade 4 neutropenia associated with fever (⩾38.5°c) or diarrhoea ⩾ grade 2, grade 4 neutropenia lasting ⩾5 days without fever, grade 4 thrombocytopenia for ⩾5 days, grade 3 or higher non-haematological toxicity (except liver transaminase elevation, or nausea or vomiting treatable by anti-emetic), and treatment delay >2 weeks before start of next cycle of treatment because of unresolved toxicity.
PubMedID- 21540759 fever with severe neutropenia was more common in patients with lrti than with urti (p = 0.02).
PubMedID- 25943747 Granulocyte colony-stimulating factors were allowed in grade 3 neutropenia with fever lasting ≥3 days or in case of grade 4 neutropenia.
PubMedID- 23975510 One of 6 patients at dose level 2 (5 mg everolimus) had grade 3 hepatotoxicity and 3 of 6 patients at level 3 (7.5 mg everolimus) had grade 4 hematologic toxicities (two grade 4 thrombocytopenia and one grade 4 neutropenia with fever lasting more than 3 days).
PubMedID- 23836852 Severe transient neutropenia with fever and abdominal pain in a 30-year-old man.

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