PedAM
Pediatric Disease Annotations & Medicines
| Disease | mental depression |
| Symptom | |chronic pain |
| Sentences | 53 |
| PubMedID- 22198556 | Intracerebroventricular 4-methylcatechol (4-mc) ameliorates chronic pain associated with depression-like behavior via induction of brain-derived neurotrophic factor (bdnf). |
| PubMedID- 24076408 | Comorbidity: current comorbid anxiety disorder, mood disorders, other axis 1 disorders, personality disorder, suicidal ideation, taking psychotropic medication; physical disability resulting from trauma, chronic pain; history of major depression, substance dependence, or suicide attempts. |
| PubMedID- 24518228 | 4-methylcatechol prevents derangements of brain-derived neurotrophic factor and trkb-related signaling in anterior cingulate cortex in chronic pain with depression-like behavior. |
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