PedAM
Pediatric Disease Annotations & Medicines
| Disease | lung cancer |
| Symptom | |brain metastases |
| Sentences | 91 |
| PubMedID- 26199015 | Introduction: the prognostic value of egfr mutation in lung cancer patients with brain metastases is uncertain and therapeutic efficacy with egfr tki is limited. |
| PubMedID- 26315660 | brain metastases develop in one-third of patients with non-small-cell lung cancer and are associated with a dismal prognosis, irrespective of surgery or chemo-radiotherapy. |
| PubMedID- 22118497 | Background: brain metastases occur in 30-50% of non-small cell lung cancer (nsclc) patients and confer a worse prognosis and quality of life. |
| PubMedID- 22613339 | Progress of treatments in non-small cell lung cancer with brain metastases. |
| PubMedID- 25646356 | Conclusions: the expression of mirna-328 and mirna-378 in tumor tissues can be used to predict brain metastases in patients with non-small-cell lung cancer. |
| PubMedID- 19740564 | Positive nuclear mgmt expression was detected more frequently in brain metastases as compared with primary lung cancers (83% versus 50%, p=0.004). |
| PubMedID- 24985049 | Limited treatment options are available for lung cancer with brain metastases. |
| PubMedID- 26359696 | brain metastases at presentation in patients with non-small cell lung cancer. |
| PubMedID- 22818215 | A 69 year old lady has an extensive small cell lung cancer with newly diagnosed brain metastases. |
| PubMedID- 23128816 | Correlation between brca1 expression and clinicopathological factors including brain metastases in patients with non-small-cell lung cancer. |
| PubMedID- 23392751 | Chemotherapy for small cell lung cancer with brain metastases. |
| PubMedID- 24376956 | Background and aim: long-term survival of lung cancer patients with brain metastases (bm) is very rare. |
| PubMedID- 23271367 | Though brain metastases, especially with lung cancer, melanoma and breast cancer, are becoming a common clinical problem, limited treatment options have existed , such as gamma knife radiosurgeries , stereotactic radiosurgery or irradiation , uvc irradiation and whole brain radiotherapy . |
| PubMedID- 26114639 | Background: the role of surgical treatment of lung cancer with brain metastases remains controversial. |
| PubMedID- 23129122 | Background: this phase ii, open-label study evaluated the efficacy and safety of erlotinib as second-line therapy in non-small-cell lung cancer (nsclc) patients with brain metastases (bm). |
| PubMedID- 23065044 | This study evaluated the efficacy of gks for treating brain metastases associated with small-cell lung cancer (sclc) after whole-brain radiotherapy (wbrt) as the first-line radiation therapy. |
| PubMedID- 26310285 | Herein, we conducted a self-controlled study to evaluate the effect of wbrt on the permeability of bbb in non-small cell lung cancer (nsclc) patients with brain metastases (bm). |
| PubMedID- 24496139 | I started looking for information 2 weeks after the definitive diagnosis of lung cancer with brain metastases had been made. |
| PubMedID- 25364413 | The patient underwent whole-brain radiotherapy based on a tentative diagnosis of lung cancer with multiple brain metastases. |
| PubMedID- 23958057 | High plasma fibrinogen concentration and platelet count unfavorably impact survival in non-small cell lung cancer patients with brain metastases. |
| PubMedID- 24256883 | Survival and treatment options are limited for patients with brain metastases arising from non-small cell lung cancer (nsclc). |
| PubMedID- 24310312 | The outcome of bifocal surgical resection in non-small cell lung cancer with synchronous brain metastases: results of a single center retrospective study. |
| PubMedID- 22220151 | Because gefitinib is effective in treating brain metastases of lung cancer with egfr mutation 7, brain metastases may have been controlled in this case. |
| PubMedID- 19592127 | Can upfront systemic chemotherapy replace stereotactic radiosurgery or whole brain radiotherapy in the treatment of non-small cell lung cancer patients with asymptomatic brain metastases. |
| PubMedID- 23189011 | Sekine et al,3 evaluated the correlation between non-small cell lung cancer patients with brain metastases and epidermal growth factor receptor (egfr) mutations on molecular studies, as well as the radiological findings. |
| PubMedID- 25208818 | The aim of this study was to explore prognostic factors for non-small cell lung cancer (nsclc) patients with brain metastases (bm) on the basis of egfr mutation status. |
| PubMedID- 26520640 | We prospectively addressed whether egfr and kras mutations, eml4-alk, ros1 and ret rearrangements, or wild-type (wt), affects radiosurgery outcomes and overall survival (os) in non-small cell lung cancer (nsclc) patients with brain metastases (bm). |
| PubMedID- 24649011 | Therapeutic strategy for non-small-cell lung cancer patients with brain metastases (review). |
| PubMedID- 25347291 | Whole brain radiotherapy plus concurrent chemotherapy in non-small cell lung cancer patients with brain metastases: a meta-analysis. |
| PubMedID- 19962229 | Short-course whole-brain radiotherapy (wbrt) for brain metastases due to small-cell lung cancer (sclc). |
| PubMedID- 25404274 | Targeted agents have become the novel methods for the treatment of lung cancer with brain metastases beyond the whole brain radiation therapy, stereotactic radiosurgery and chemotherapy. |
| PubMedID- 20658721 | Gamma knife radiosurgery in non small cell lung cancer patients with brain metastases: treatment results and prognostic factors. |
| PubMedID- 24790650 | This review is focused on the evidence for therapeutic strategies in bone and brain metastases due to lung cancer. |
| PubMedID- 26275366 | Delayed leukoencephalopathy of non-small cell lung cancer patients with brain metastases underwent whole brain radiation therapy. |
| PubMedID- 22335887 | Although the presence of epidermal growth factor receptor (egfr) mutation and good response to gefitinib have been reported in non-small cell lung cancer (nsclc) patients with miliary brain metastases, the influence of the egfr mutations on the radiographic features remains unclear. |
| PubMedID- 22490154 | Evaluation of gefitinib plus radiotherapy in non-small-cell lung cancer patients with brain metastases. |
| PubMedID- 21924038 | The aim of this study is to explore prognostic factors in non-small cell lung cancer (nsclc) in patients with brain metastases diagnosed by constrast-enhanced mri after whole brain radiotherapy. |
| PubMedID- 22461932 | Past medical history was notable for small cell lung cancer (sclc) with brain metastases. |
| PubMedID- 25556163 | Rapid response of brain metastases to alectinib in a patient with non-small-cell lung cancer resistant to crizotinib. |
| PubMedID- 23133721 | Multiple gamma knife radiosurgery for multiple metachronous brain metastases associated with lung cancer : survival time. |
| PubMedID- 22917813 | This study was designed to determine if maintenance enzastaurin improved the outcome of whole brain radiotherapy (wbrt) in lung cancer (lc) patients with brain metastases (bms). |
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