PedAM
Pediatric Disease Annotations & Medicines
| Disease | liver disease |
| Symptom | |cirrhosis |
| Sentences | 175 |
| PubMedID- 24282628 | Nash, but not simple steatosis, is a potentially progressive liver disease leading to cirrhosis and hepatocellular carcinoma . |
| PubMedID- 21181919 | Multivariate analysis revealed that t1762/a1764 double mutation, hbv/a, age >/=25 years, c1753 and a1899 were critical factors for clinical advancement while age >/=25 years and c1753 as significant predictor for cirrhosis in comparison with chronic liver disease. |
| PubMedID- 21810745 | Among the systemic diseases that allocated patients to asa score >2, chronic liver disease including cirrhosis was significantly more frequent in patients with treatment failure than in those with remission (8 of 21 vs 9 of 77; p = .01). |
| PubMedID- 21697972 | Our patient had an ill-defined chronic liver disease with no cirrhosis on biopsy, was on a low and tapering dose of steroids for a short period of time, and was taking 6-mp. |
| PubMedID- 24581591 | For the diagnosis of the so-called idiopathic ncph, it is essential to rule out chronic liver diseases associated with progression to cirrhosis as viral hepatitis b and c, alcoholic and non-alcoholic fatty liver, autoimmune disease, hereditary hemochromatosis, wilson's disease as well as primary biliary cirrhosis and primary sclerosing cholagitis. |
| PubMedID- 25821463 | Patients were excluded if they had hcv genotype other than type 1 infection (i.e., hcv types 2–6), biopsy-proven cirrhosis, other causes of liver disease, hepatitis b virus infection, human immunodeficiency virus infection, autoimmune disorders, clinically significant cardiac or cardiovascular abnormalities, organ grafts, systemic infections, clinically significant bleeding disorders, evidence of malignant neoplastic diseases, concomitant immunosuppressive medication, fasting glucose levels >7 mmol/l or glucose levels >11.1 mmol/l at 2 hours after an oral intake of 75 grams of glucose (oral glucose tolerance test) or glycosylated hemoglobin > 48 mmol/mol (6.5%) or antidiabetic treatment, or any alcohol intake or drug abuse within the six months prior to study entry. |
| PubMedID- 25635922 | Easl guidelines state that the primary goal of hcv therapy is to cure the infection, which is generally associated with resolution of liver disease in patients without cirrhosis 5. |
| PubMedID- 23610585 | Inefficient local immunity was demonstrated in liver disease; patients with cirrhosis in particular. |
| PubMedID- 25977695 | According to our findings, we recommend correction of vitamin d level in chronic liver disease, especially in patients with cirrhosis to maintain their bone density. |
| PubMedID- 23418453 | Approximately 170 million people are chronically infected with hcv, and some develop progressive liver disease which may lead to cirrhosis, hepatocellular carcinoma and death 2. |
| PubMedID- 26247932 | Hepatitis b virus (hbv) attacks the liver and can cause both acute as well as chronic liver diseases which might lead to liver cirrhosis and hepatocellular carcinoma. |
| PubMedID- 22645408 | Exclusion criteria: hcv-infected patients treated with interferon α in the past six months or less, liver cirrhosis, other types of hepatitis or liver disease of different etiology, other infectious diseases, overt cardiovascular disease (based on documented history and ecg examination), endocrine diseases, lung disease, renal dysfunction (serum creatinine level >2.0 mg/dl), presence or history of neoplastic diseases, pregnant or postpartum women, and present or past history of alcohol or drug abuse. |
| PubMedID- 20399524 | Excess weight is an independent risk factor for steatosis, acute alcoholic hepatitis (aah), and cirrhosis in patients with alcoholic liver disease (ald). |
| PubMedID- 24159587 | The major reasons for the increased incidence of hcc in the us are the increasing prevalence of chronic hcv infection, increased immigration from high-incidence countries in asia and africa, and the increase in the number of individuals with cirrhosis due to obesity-related fatty liver disease. |
| PubMedID- 26076199 | Liver fibrosis is a common feature of almost all causes of chronic liver disease, and eventually leads to cirrhosis . |
| PubMedID- 25945106 | Liver fibrosis represents the final common pathway of chronic liver diseases and eventually leads to cirrhosis and its complications including liver failure and hepatocellular carcinoma . |
| PubMedID- PMC3580826 | Hepatitis d virus (hdv) coinfected with hbv is most often associated with a severe and progressive liver disease leading to cirrhosis more rapidly than hepatitis b alone and are more resistant to standard antiviral drugs (51). |
| PubMedID- 22848732 | However, te and arfi (right liver lobe) distinguished between liver cirrhosis and earlier stages of liver disease in cfld patients. |
| PubMedID- 26488159 | History of decompensated cirrhosis or other causes of liver disease identified in hiv-infected patients, such as nash or drug-induced liver injury, was not collected as well as other comorbidities, including renal failure. |
| PubMedID- 25553238 | Approximately 20% of those chronically infected will ultimately progress to develop cirrhosis and death due to end-stage liver disease or hepatocellular carcinoma (hcc). |
| PubMedID- 20716942 | In addition, chronic alcoholic liver disease (ald), with or without cirrhosis, increases risk for hepatocellular carcinoma (hcc). |
| PubMedID- 24974878 | Conclusion: ir is common in euglycemic cirrhosis and with advancement of liver disease; there is a compensatory increase in pancreatic beta-cell insulin secretion to overcome the ir. |
| PubMedID- 22235351 | Older age, male sex, cirrhosis and sustained activity of liver disease are important predicators for hcc5. |
| PubMedID- 26447841 | more than 80% of hcc arise in a background of chronic liver disease with liver cirrhosis caused by chronic hepatitis b or c virus infection, alcohol abuse or obesity with non-alcoholic fatty liver disease. |
| PubMedID- 20174556 | The hepatitis c virus (hcv) is a major cause of chronic liver disease worldwide, leading to cirrhosis and hepatocellular carcinoma 1. |
| PubMedID- 25922775 | It is estimated that the main causes of liver disease leading to cirrhosis and/or hcc in europe include hepatitis c (hcv) infection in 60% of patients, hepatitis b (hbv) infection in 15% of patients, and alcohol abuse in 10% of patients. |
| PubMedID- 21743215 | Hcv is a major cause of chronic liver disease that may lead to cirrhosis and hepatocellular carcinoma. |
| PubMedID- 23202682 | This study has found that death from chronic liver disease, including cirrhosis, on the county level in north carolina’s 100 counties correlates with on-road concentrations of manganese. |
| PubMedID- 24533141 | cirrhosis is a consequence of chronic liver disease characterized by the replacement of liver tissue by fibrosis, scar tissue, and regenerative nodules, which leads to loss of liver function. |
| PubMedID- 25678995 | A diagnostic model for cirrhosis in patients with non-alcoholic fatty liver disease: an artificial neural network approach. |
| PubMedID- 25337145 | Background: a single nucleotide polymorphism (snp) of patatin-like phospholipase domain-containing 3 (pnpla3) genes (rs738409) is associated with the severity of fibrosis and cirrhosis in patients with fatty liver disease. |
| PubMedID- 25922602 | We constructed a stepwise logistic regression using age, meld at lt, hepatitis c (hcv) cirrhosis as a cause of the liver disease, and presence of a combined liver-kidney transplant to determine whether the covariates accounted for differences in recipient qol scores. |
| PubMedID- 21687605 | Among patients with cirrhosis, the severity of liver disease were as follows: child pugh a n = 11, child pugh b n = 15, and child pugh c n = 21. stages of fibrosis in noncirrhotic patients were as follows: stage 1 n = 10, stage 2 n = 7, stage 3 n = 3, and stage 4 n = 1 (table 1). |
| PubMedID- 24046790 | Egy-score predicts severe hepatic fibrosis and cirrhosis in egyptians with chronic liver diseases: a pilot study. |
| PubMedID- 24367208 | It is intriguing that all chronic liver diseases eventually lead to liver cirrhosis and the sequence of steatosis, steatohepatitis and fibrosis/cirrhosis is generally accepted as causative. |
| PubMedID- 22139986 | Common indications for olt include cirrhosis due to alcoholic liver disease or chronic viral hepatitis related to hepatitis b or c, and hepatocellular carcinoma. |
| PubMedID- 21852972 | The associations with hepatocellular carcinoma (pon1) and cholangiocellular carcinoma (pon3) also seem to be plausible as paraoxonases have a protective effect against oxidative stress, which plays an important role in chronic liver diseases leading to liver cirrhosis and the development of carcinomas (camps et al., 2009). |
| PubMedID- 25191050 | Chronic liver disease with cirrhosis and hepato-cellular carcinoma is the other spectrum of the disease. |
| PubMedID- 21520174 | Conclusion: this study provides the first experimental evidence that telomerase gene mutations are present in patients developing cirrhosis as a consequence of chronic liver disease. |
| PubMedID- 22801423 | Hepatitis c virus (hcv) is the main agent of acute and chronic liver diseases leading to cirrhosis and hepatocellular carcinoma. |
| PubMedID- 24901158 | Background/aims: liver cirrhosis is the end-stage of various liver diseases, which has a poor prognosis and determined by deterioration of hepatic functional capacity and consecutive development of hepatic complications. |
| PubMedID- 26058465 | Persistent hbv infection can promote liver disease, thereby leading to hepatitis and cirrhosis . |
| PubMedID- PMC4070603 | So, marked increase in serum levels are noted in liver diseases, especially in patients with cirrhosis, when the clearance is impaired. |
| PubMedID- 25462064 | While alcohol is necessary for the development of ald, only 20-30% of alcoholics develop alcoholic steatohepatitis (ash) with progressive liver disease leading to cirrhosis and liver failure (ald). |
| PubMedID- 26117383 | Severe mdr3 deficiency typically presents during the first year of life or early childhood, often progressing to chronic liver disease with cirrhosis and portal hypertension, requiring liver transplantation. |
| PubMedID- 25736154 | Letter: proton pump inhibitors - severity of liver disease and mortality in patients with cirrhosis - authors' reply. |
| PubMedID- 26099526 | Background & aims: alcoholic steatohepatitis (ash) is the progressive form of alcoholic liver disease and may lead to cirrhosis and hepatocellular carcinoma. |
| PubMedID- 24490061 | Most patients had cirrhosis due to alcoholic liver disease (table 1). |
| PubMedID- 23819582 | Hcc is often complicated by cirrhosis, so treatment of the underlying liver diseases is also necessary to improve the prognosis. |
| PubMedID- 23243430 | Hepatic fibrosis is a common response to most chronic liver diseases, which may lead to cirrhosis, and cause liver failure as well as increase the risk for hepatocellular carcinoma. |