PedAM
Pediatric Disease Annotations & Medicines
| Disease | colorectal cancer |
| Symptom | |liver metastasis |
| Sentences | 98 |
| PubMedID- 26552809 | Increased slex was reported in liver metastasis of colorectal cancer, and was associated with poor patient survival and early recurrence in colorectal carcinoma . |
| PubMedID- 24953371 | Methods: a total of 30 colorectal cancer patients with synchronous liver metastasis underwent radical resection of primary cancer and liver cancer in our hospital from june 2001 to june 2010. |
| PubMedID- 21624121 | Ccl20 and/or ccr6 expression have been reported in pancreatic and colorectal cancer and correlates with invasion and liver metastasis . |
| PubMedID- 24489916 | 20%–25% of colorectal cancer patients present with simultaneous liver metastasis at the time of diagnosis and a few patients are evaluated with primary tumor and liver metastasis resectable synchronously 1. |
| PubMedID- 26218533 | However, the sensitivity of pet/ct markedly decreased after chemotherapy and many colorectal cancer patients with liver metastasis underwent chemotherapy before or after surgery, hence pet/ct could not completely replace contrast enhanced ct or mr . |
| PubMedID- 22057187 | Efficacy of oxaliplatin-based chemotherapy in curatively resected colorectal cancer with liver metastasis. |
| PubMedID- 21153819 | Risk factors for the development of metachronous liver metastasis in colorectal cancer patients after curative resection. |
| PubMedID- 25866690 | Designed a phase iii randomized clinical trial to define the role of y90 radioembolization in colorectal cancer with liver metastasis. |
| PubMedID- 21174058 | Of these, 4 mirnas including mir-150*, mir-125b-2*, mir-1179 and mir-139-3p were up-regulated in colorectal cancers with liver metastasis while the others were down-regulated. |
| PubMedID- 24448820 | Cluster analysis (7 colorectal cancer patients with liver metastasis and 12 colorectal cancer patients without liver metastasis) indicated that mir-340 and mir-542-3p expressions were significantly decreased in epcam(+) bone marrow cells of patients with liver metastasis (p = 0.019 and 0.037, respectively). |
| PubMedID- 23356713 | The hr for colorectal cancer with liver metastasis was 0.42 but those from prostate (0.25) and breast (0.31) cancer were even more favorable. |
| PubMedID- 22314329 | Predictive factors for the benefit of perioperative folfox for resectable liver metastasis in colorectal cancer patients (eortc intergroup trial 40983). |
| PubMedID- 21060790 | Primary colorectal cancer with paired liver metastasis (n = 23): identification of recurrent chromosomal breakpoint regions for the 1p12, 8p12, 17p11.2 and 20p12.1 chromosome regions as defined by the affymetrix 500k snp array genotyping platform. |
| PubMedID- 24550602 | Survival rates for liver metastasis of colorectal cancer are comparable . |
| PubMedID- 22084593 | In endometrial cancer, ovarian cancer and high-grade osteosarcomas, respectively, ido expression correlates with poor overall survival.34–36 furthermore, our own group was able to show that ido had a significant prognostic value in terms of liver metastasis in patients with colorectal cancer. |
| PubMedID- 20683000 | Overexpression of mmp-13 gene in colorectal cancer with liver metastasis. |
| PubMedID- 26448934 | Had clarified that strong expression of galectin-3 in colorectal cancer correlated with cancer progression, liver metastasis, and poor prognosis . |
| PubMedID- 22073198 | In summary, we have developed a highly optimized mouse model for liver metastasis of colorectal cancer, which allows detection of the tumor load at the whole body level and enables an accurate timing of therapeutic interventions to target different stages of cancer progression and metastatic development. |
| PubMedID- 26263637 | colorectal cancer with synchronous liver metastasis (sm-crc) is extremely unfavorable prognostic factor. |
| PubMedID- 22403747 | In colorectal and breast cancer patients, an elevation in the serum il-2rα level indicates disease progression to stage iv or liver metastasis with colorectal cancer, and distant metastasis in breast cancer 8. |
| PubMedID- 23801208 | Conclusions: decrease of the number of t lymphocyte and mast cell may play an important role in local infiltration of immune microenvironment of stage iii to iiii colorectal cancer with liver metastasis. |
| PubMedID- 24518602 | Similarly, high serum levels of scxcl16 in colorectal cancer patients were associated with recurrent liver metastasis and poor prognosis (matsushita et al, 2012). |
| PubMedID- 23172529 | Objective: to analyze the relationship of k-ras mutation with the development of liver metastasis in colorectal cancer patients and the survival outcomes. |
| PubMedID- 24972738 | Serum cd10 is associated with liver metastasis in colorectal cancer. |
| PubMedID- 24324891 | Similar results were published by vogl and coworkers in 2009 and pohlen and coworkers in 2006 for patients with liver metastasis of colorectal cancer. |
| PubMedID- 24972972 | Aberrant s1pr1 expression in colorectal cancer was associated with metachronous liver metastasis and worse survival outcome, and also, it was an independent prognostic factor. |
| PubMedID- 24444095 | Hsa-mir-579 was a down-regulated mirna of ovarian cancer samples, and mir-579 is found to dysregulated in colorectal cancer with liver metastasis . |
| PubMedID- 21152140 | Nevertheless, in a study that evaluated the usefulness of chest ct for the assessment of the presence of pulmonary metastasis prior to a lung metastasectomy in colorectal cancer patients with liver metastasis, the positive prediction rate was not significantly different from that for chest radiography; thus, its usefulness was low . |
| PubMedID- 21390153 | Hbv infection decreases risk of liver metastasis in patients with colorectal cancer: a cohort study. |
| PubMedID- 26146543 | The expression of mir-340 is significantly decreased in bone marrow cells of colorectal cancer patients with liver metastasis. |
| PubMedID- 22740990 | Carcinoembryonic antigen and carbohydrate antigen 19-9 are prognostic predictors of colorectal cancer with unresectable liver metastasis. |
| PubMedID- 22945388 | Methodology: the study involved 55 patients of colorectal cancer with liver metastasis who underwent surgery at our department between february 1988 and april 2003. |
| PubMedID- 25970784 | The serum il6 and il8 levels were significantly increased in the colorectal cancer patients with liver metastasis . |
| PubMedID- 23721165 | Establishment of a predictive genetic model for estimating chemotherapy sensitivity of colorectal cancer with synchronous liver metastasis. |
| PubMedID- 20206548 | Current data support the use of hepatectomy for well-selected elderly colorectal cancer patients with liver metastasis; however, this and other evolving therapies need to be assessed in the elderly to better define their role, indications, safety and outcomes. |
| PubMedID- 24851215 | In a similar mouse model in which liver metastasis of colorectal cancer was induced, the sizes of the primary cancer and the liver metastatic lesion were greatly decreased with the injection of both monoclonal antibody to α5β1-integrin and fluorouracil, and this reduction seemed to be greater than it was in other groups that received fluorouracil only . |
| PubMedID- 26092596 | Expression of cancer stem cell markers in metastatic colorectal cancer correlates with liver metastasis, but not with metastasis to the central nervous system. |
| PubMedID- 21829768 | In addition, in a study conducted on liver metastasis of colorectal cancer, zeng et al. |
| PubMedID- 24363829 | We herein review past, present, and possible future markers of prognosis among colorectal cancer patients with liver metastasis undergoing resection with curative intent. |
| PubMedID- 23443137 | liver metastasis in colorectal cancer is the major cause of cancer-related deaths. |
| PubMedID- 23302486 | Objective: to investigate pik3ca, pten status in the primary lesion of colorectal cancer (crc): relationship with occurrences of liver metastasis and its prognosis. |
| PubMedID- 24334302 | Apoptotic circulating tumor cells (ctcs) in the peripheral blood of metastatic colorectal cancer patients are associated with liver metastasis but not ctcs. |
| PubMedID- 22937765 | The number of colorectal cancer patients with liver metastasis was not many. |
| PubMedID- 23991968 | Patients and methods: ve of liver metastases was performed by manual contouring before and after chemotherapy on 45 pairs of computed tomography (ct) images in 36 patients who suffered from metastatic colorectal cancer (mcrc) with liver metastasis only. |
| PubMedID- 24760176 | Downregulation of mir-214 is specific of liver metastasis in colorectal cancer and could play a role determining the metastatic niche. |
| PubMedID- 25326396 | Pulmonary metastasectomy in colorectal cancer patients with previously resected liver metastasis: pooled analysis. |
| PubMedID- 24263311 | Predictive factors for the benefit of perioperative folfox for resectable liver metastasis in colorectal cancer patients (eortc intergroup trial 40983). |
| PubMedID- 24667486 | Lymph node-independent liver metastasis in a model of metastatic colorectal cancer. |
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