PedAM
Pediatric Disease Annotations & Medicines
| Disease | breast cancer |
| Symptom | |obesity |
| Sentences | 117 |
| PubMedID- 26388139 | The associations of obesity with postmenopausal breast cancer (pbc) have been previously proven in clinical studies. |
| PubMedID- 23212604 | Results: compared to all other racial/ethnic groups, more white females reported heavy alcohol consumption and more black females reported obesity regardless of their breast cancer status. |
| PubMedID- 25364153 | Association of overweight and obesity with breast cancer in india: scope for improvement. |
| PubMedID- 21198265 | Results: there was an increased risk of breast cancer associated with overweight or obesity in adulthood in chinese women. |
| PubMedID- 22186408 | obesity is frequently associated with breast cancer. |
| PubMedID- 24392267 | It confirmed that obesity at diagnosis of early-stage breast cancer is an independent prognostic factor for the development of distant metastases and death after the diagnosis of breast cancer . |
| PubMedID- 25747851 | obesity in breast cancer--what is the risk factor. |
| PubMedID- 24118876 | To examine breast cancer relationships with obesity and central adiposity independently, our analytic strategy involved generating mutually adjusted risk estimates. |
| PubMedID- 20711654 | On the contrary, nulliparity and obesity decrease the risk of early-onset breast cancers while are associated with higher incidence in older women. |
| PubMedID- 21878422 | Interaction between smoking and obesity and the risk of developing breast cancer among postmenopausal women: the women's health initiative observational study. |
| PubMedID- 20821253 | Recently, adipose tissue and its associated cytokine-like proteins, adipokines, particularly leptin and adiponectin, have been investigated as mediators for the association of obesity with breast cancer. |
| PubMedID- 21071885 | obesity increases the risk of breast cancer in postmenopausal women through a hormonal mechanism involving the metabolism of an androgenic precursor to estrogen in adipose tissue,24,25 and estrogen influences breast parenchyma proliferation.20,26–28 thus, obesity may be involved in the associations of hdl-c with mammographic density and breast cancer. |
| PubMedID- 24489874 | Yet, in japanese women, evidence has shown that breast cancer risk with post-menopausal obesity was modified by pr status alone, not by er status 7. |
| PubMedID- 19898898 | Background: obesity is associated with poorer breast cancer-specific survival. |
| PubMedID- 20621848 | We coded the responses into exogenous (e.g., pesticides, toxicants, and phthalates) and endogenous (e.g., diet, stress, obesity) environmental causes of breast cancer. |
| PubMedID- 21194473 | The one unexpected observation was that obesity was not associated with breast cancer risk in women aged 55 years and older (or = 0.96, 95% ci 0.88 to 1.04). |
| PubMedID- 23104221 | The models estimate that the fraction of the us breast cancer cases attributable to obesity is 3.9-4.5 % (range across models) for whites and 2.5-3.6 % for blacks. |
| PubMedID- 23346172 | The purpose of this study was to evaluate the predictive or prognostic value of obesity in breast cancer receiving neoadjuvant chemotherapy. |
| PubMedID- 26560078 | Whether the effect of irisin on breast cancer can be attributed to obesity-related hyperinsulinemia and insulin resistance extends beyond the scope of this work, but is a particularly interesting field of research that is worthy of thorough investigation in future studies. |
| PubMedID- 21750966 | A gene transcription signature of obesity in breast cancer. |
| PubMedID- 25583948 | Background: although obesity is associated with breast cancer incidence and prognosis, the underlying mechanisms are poorly understood. |
| PubMedID- 22992276 | Conclusions: decreasing parity and increasing obesity are determinants of increasing breast cancer incidence among iranian women. |
| PubMedID- 25923423 | Many possible mechanisms have been proposed to explain the increased risk of breast cancer associated with obesity such as increased lipids and lipid signaling, inflammatory responses, insulin resistance, adipokines, altered immune responses, and oxidative stress. |
| PubMedID- 24833917 | Although there is no conclusive evidence to suggest the protective role of specific dietary components, alcohol consumption and obesity are associated with an increased breast cancer risk; thus lifestyle changes can lead to a lower risk of developing breast cancer. |
| PubMedID- 25468909 | obesity is associated with increased breast cancer (brca) incidence. |
| PubMedID- 23829168 | Both cohort and case–control epidemiological observations have demonstrated the association of metabolic syndrome, obesity and diabetes with increased breast cancer risk . |
| PubMedID- 23625540 | obesity increases the incidence of breast cancer; 5.4%-5.6% of cases expected to occur in 2025 would be attributable to obesity if current rates are maintained (table 3). |
| PubMedID- 24647890 | obesity was inversely associated with breast cancer among younger women and positively associated with risk for older women (interaction p < 0.0001). |
| PubMedID- 26359358 | Leptin, a major adipocytokine produced by adipocytes, is emerging as a key molecule linking obesity with breast cancer therefore, it is important to find effective strategies to antagonize oncogenic effects of leptin to disrupt obesity-cancer axis. |
| PubMedID- 26182172 | Conclusions and relevance: obesity is associated with increased invasive breast cancer risk in postmenopausal women. |
| PubMedID- 25476497 | obesity is associated with a worse breast cancer prognosis, particularly in estrogen receptor alpha (eralpha) positive, postmenopausal patients. |
| PubMedID- 24935119 | The increased risk of breast cancer that is associated with obesity has been widely reported; this has drawn much attention and as such, warrants investigation of the key mechanisms that link the obese state with cancer aetiology. |
| PubMedID- 26518195 | obesity, ethnicity, and quality of life among breast cancer survivors and women without breast cancer: the long-term quality of life follow-up study. |
| PubMedID- 24218051 | obesity is associated with basal-like breast cancer (bbc), an aggressive breast cancer subtype. |
| PubMedID- 20584344 | For example, pabc and postmenopausal breast cancer associated with obesity are both diagnosed at a later stage, do not respond well to current therapies and confer an overall poorer patient prognosis. |
| PubMedID- 25252818 | Objectives: several studies suggest that overall and central-obesity are associated with increased breast cancer (bc) risk in postmenopausal-women. |
| PubMedID- 25361993 | obesity and the outcome of young breast cancer patients in the uk: the posh study. |
| PubMedID- 26199932 | A direct relationship has been observed between obesity and increased risk of breast cancer 3. |
| PubMedID- 24834284 | Mediators such as cytokine-like proteins, adipokines, particularly leptin and adiponectin, have been indentified to be obesity with breast cancer related factors (31). |
| PubMedID- 20604969 | obesity is also associated with breast cancer risk; estrogen synthesis in adipose tissue is proposed to account for this increase in risk. |
| PubMedID- 25856214 | Childhood obesity increases breast cancer death risk in women, but levels of estrogen derivatives had not been previously studied in young children. |
| PubMedID- 22562122 | Evidence regarding associations of obesity with breast cancer-specific survival (bcss) and overall survival (os) in relation to hormone receptor status, or bcss in relation to menopausal status has not been evaluated in a previous meta-analysis. |
| PubMedID- 24506358 | obesity combined with breast cancer is a public health problem, given the high incidence and prevalence of both diseases. |
| PubMedID- 25823469 | Epidemiological studies have linked obesity with basal-like breast cancer risk and poor disease outcome, suggesting that obesity may affect the tumor phenotype by skewing the microenvironment toward support of more aggressive tumor phenotypes. |
| PubMedID- 23374911 | obesity is increasingly associated with postmenopausal breast cancer risk , whereas, in premenopausal women there is an inverse relation between bmi and breast cancer risk . |
| PubMedID- 25793921 | obesity is associated with poor breast cancer (bc) prognosis. |
| PubMedID- 23833528 | A single-stop approach, especially in high risk women (obesity, diabetes, family history of endometrial, ovarian or breast cancer) as well as in women with endometrial hyperplasia of combining the office hysteroscopy, directed biopsy in presence of a focal lesion, and vacuum sampling of endometrium in normal looking endometrium, all without anesthesia is the most minimally invasive and yet accurate approach in current practice. |
| PubMedID- 22268396 | Regardless of menopausal status, obesity is associated with breast cancers that exhibit aggressive biological characteristics at the time of diagnosis and have a poor prognosis; a similar relationship is emerging for type 2 diabetes. |
| PubMedID- 24665149 | Observed that these two factors separately or in combination influence the body weight and obesity increases the risk of breast cancer in post-menopausal women.7 dumitrescu and cotarla supported this observation in their paper and noted that breast cancer risk is particularly evident among obese women who do not use hormone replacement therapy (hrt), and for each 5 kg of weight gain, breast cancer risk increases by 8%.1 this is explained by the fact that fat in adipose tissue is an important source of oestrogens, which are synthesised from cholesterol. |
| PubMedID- 23764995 | Environmental exposures, namely parity and obesity modified the effect of both snps on breast cancer risk in ea. |