PedAM
Pediatric Disease Annotations & Medicines
| Disease | vascular disease |
| Symptom | |diabetes |
| Sentences | 526 |
| PubMedID- 25298426 | These findings demonstrate that glp-1 as well as its analogs (glp-1-related reagents) may hold therapeutic potential in the treatment of diabetes with cardiovascular disease. |
| PubMedID- 22340758 | Cardiovascular diseases (cvd) in patients with type 2 diabetes are a large and increasing health problem. |
| PubMedID- 26055067 | This paper describes the relationship of baseline fgf21 levels and new on-study microvascular disease in patients with type 2 diabetes from the field study. |
| PubMedID- 24089540 | In obese patients with type 2 diabetes and high risk of cardiovascular disease, monotherapy with metformin or diet-only treatment was associated with lower risk of cardiovascular events than treatment with insulin. |
| PubMedID- 26171855 | Standardized questionnaires were performed in all patients to collect information regarding age, gender, underlying systemic diseases such as diabetes, hypertension, history of cerebrovascular diseases, and hyperlipidemia, dietary habit, smoking history and body mass index (bmi). |
| PubMedID- 25217178 | Background: the role of statins in the development of microvascular disease in patients with diabetes is unknown. |
| PubMedID- 20047771 | Leisure-time physical activity and risk of type 2 diabetes in patients with established vascular disease or poorly controlled vascular risk factors. |
| PubMedID- 26557879 | Although aspirin has been in clinical use for more than a century, there is still much to be learned about its future uses, particularly in cancer and in patients who are at particularly high risk of cardio- and cerebrovascular diseases—such as those with diabetes mellitus and long-term survivors of hiv infection. |
| PubMedID- 20700576 | Oral disease and subsequent cardiovascular disease in people with type 2 diabetes: a prospective cohort study based on the action in diabetes and vascular disease: preterax and diamicron modified-release controlled evaluation (advance) trial. |
| PubMedID- 25856787 | Data obtained from epidemiological studies have clearly demonstrated that diabetic retinopathy (dr), a common chronic microvascular complication of diabetes, is associated with macrovascular disease . |
| PubMedID- 22210236 | Objective: depression in type 2 diabetes is associated with obesity, cardiovascular disease, and mortality. |
| PubMedID- 23723672 | One of the early markers of not only diabetic nephropathy, but also vascular disease in patients with diabetes, is the presence of microalbuminuria. |
| PubMedID- 26060511 | (2006)patients with diabetes free of vascular disease, receiving repaglinide or glibenclamide; italy12-month trial on glycemic control156mean 74 ± 2 yearsvariation in post-prandial blood glucose, fasting plasma glucose, and hba1c. |
| PubMedID- 25733983 | We attempted to evaluate the risk of ischemic stroke preferentially, because incidence rate for ischemic stroke was greater than any other cardiovascular diseases among patients with diabetes 8. |
| PubMedID- 24404539 | Clinically diagnosed diabetes mellitus with cardiovascular disease (dm+cvd) shall be the endpoint. |
| PubMedID- 23938049 | Dyslipidemia, undesirable changes in vascular endothelial and smooth muscle cells, lipid peroxidation especially oxidized low-density lipoprotein particles, oxidative damage and increased inflammatory mediators including chemokines and cytokines, hyper-coagulation and platelet activation have been considered as the main metabolic abnormalities in diabetes mellitus leading to cardiovascular disease . |
| PubMedID- 23961478 | For high-risk patients, ldl-c treatment goal was ldl <100 mg/dl but an ldl-c goal of <70 mg/dl was considered a therapeutic option for very high risk patients who had recent heart attacks, cardiovascular disease with diabetes, metabolic syndrome, or severe/poorly controlled risk factors. |
| PubMedID- 22860108 | Gender, diabetes, family history of cardiovascular disease, smoking and sedentary habitus, blood pressure, and biochemical variables did not distinguish survivors and non-survivors. |
| PubMedID- 24126880 | Therefore, we evaluate coronary arteries as well as coronary microvascular disease (associated with diabetes and hypertension), suspected or overt dilated cardiomyopathy, systolic and diastolic heart failure, hypertrophic cardiomyopathy, athletes' hearts, valvular heart disease, congenital heart disease, incipient or overt pulmonary hypertension, and heart transplant patients for early detection of chronic or acute rejection as well as potential donors for better selection of suitable donor hearts. |
| PubMedID- 26177960 | In contrast with the severe systemic vascular disease associated with diabetes, clinically relevant pulmonary vascular disease is uncommon in diabetics. |
| PubMedID- 23717466 | Insulin resistance (ir), a pathogenic factor for type 2 diabetes . |
| PubMedID- 23029252 | Adjusted for age, sex, diabetes, smoking, family history of cardiovascular disease and baseline levels of nt-probnp, ck-mb and tnt. |
| PubMedID- 22523674 | As with increasing adiposity in aging and loss of muscle mass, the insulin-mediated glucose uptake and tg disposal in the skeletal muscle of elderly persons is reduced and the maintenance of a large muscle mass can contribute to the prevention of type 2 diabetes, which is associated with cardiovascular disease. |
| PubMedID- 23547796 | Predisposing factors such as diabetes and immunosuppression lead to vascular disease and suppressed immunity that increase susceptibility to polymicrobial infection. |
| PubMedID- 20847892 | Evidence suggests that the maintenance of a large muscle mass may reduce metabolic risk factors—namely, obesity, dyslipidaemia, and type 2 diabetes mellitus—associated with cardiovascular disease . |
| PubMedID- 24672797 | The pathophysiology of vascular disease in diabetes involves abnormalities in endothelial, vascular smooth muscle cell and platelet function. |
| PubMedID- 20357382 | Management of diabetes in patients with cardiovascular disease is complicated by the fact that the cardiovascular safety of some oral glucose–lowering agents has been questioned, and outcome data are lacking (8). |
| PubMedID- 22436702 | In patients with diabetes, the major cause of death is macrovascular disease , and in individuals with type 2 diabetes, the main etiology for up to 75% of the mortality is atherosclerotic cardiovascular disease 4. |
| PubMedID- 22860025 | All these observations show that individuals with ifg have higher risk for conversion to diabetes, development of atherosclerosis and cardiovascular diseases in future. |
| PubMedID- 21264179 | The pathophysiology of vascular disease in diabetes involves abnormal function of the vascular endothelial and smooth muscle cells (smc) as well as platelets. |
| PubMedID- 25849783 | Background: both non-alcoholic fatty liver disease (nafld) and type 2 diabetes increase the risk of developing cardiovascular disease. |
| PubMedID- 23035799 | There are very few studies that have reported factors associated with cardiovascular disease control in patients with diabetes, as opposed to adults in general, irrespective of diabetes status. |
| PubMedID- 22719800 | Cardiovascular disease in diabetes is linked to increased risk of atherosclerosis, increased levels of triglyceride-rich lipoproteins and enhances hepatic lipogenesis. |
| PubMedID- 24512719 | The deleterious effects of glucotoxicity have an important role in the progressive impairment of insulin secretion and sensitivity, two major factors in the pathogenesis of type 2 diabetes, which can lead to future microvascular diseases or others complications 1. |
| PubMedID- 25285280 | approximately, 80% of deaths in patients with diabetes are attributable to cardiovascular disease (cvd). |
| PubMedID- 26120352 | We believe that our findings will provide fundamental insights for the prevention and treatment of cardiovascular diseases in patients with diabetes and hhcy. |
| PubMedID- 26089876 | Two adjacent regions upstream cdkn2b on chromosome 9p21 have been associated with type 2 diabetes (t2d) and progression of cardiovascular disease (cvd). |
| PubMedID- 23887188 | A similar model indicated that in the past five years; aging, diabetes duration and presence of cardiovascular disease were inversely related factors to having been vaccinated for pneumococcal disease. |
| PubMedID- 25191571 | Dietary strategies for alleviating health complications, such as premature vascular disease,associated with type 2 diabetes (t2d) and obesity are actively being pursued as alternativesto pharmaceutical interventions(1). |
| PubMedID- 26516107 | The aim of this study was to analyse all-cause mortality and cardiovascular disease (cvd) outcomes in patients with type 2 diabetes detected by screening or diagnosed clinically. |
| PubMedID- 20507274 | Since statins are drugs commonly prescribed for the prevention of cardiovascular disease even in patients with prediabetes or diabetes, it is of great importance to identify the role of statin treatment on glucose homeostasis. |
| PubMedID- 20587725 | Those with diabetes had no history of hypertension or macrovascular disease, and microvascular disease was excluded. |
| PubMedID- 26314713 | As a result, more hiv-infected patients die of cardiovascular diseases, with diabetes being one of the main risk factors. |
| PubMedID- 26257973 | This disorder is a rare complication of poorly controlled diabetes, usually occurring in patients with preexisting microvascular disease. |
| PubMedID- 24427312 | Post hoc analysis from the prospective pioglitazone clinical trial in macrovascular events (proactive) investigated the relationship between chronic kidney disease and the incidence of cardiovascular disease in patients with diabetes and documented macrovascular disease, as well as the effects of pioglitazone treatment on recurrent cardiovascular disease, and found that pioglitazone was more effective than placebo in reducing the rate of both primary and secondary composite end points in the patients with chronic kidney disease. |
| PubMedID- 24903023 | Obesity and overweight are associated with comorbidities such as type ii diabetes, various types of cancer and cardiovascular diseases , conditions that may contribute to reducing individual ability to work . |
| PubMedID- 22870927 | Among 1849 subjects, 669 (mean age 55.3+/-8.8 years; 392 men) with ft4 and tsh in the normal ranges were included after excluding those with diabetes, a history of current smoking and cardiovascular disease (cvd), or the use of drugs for hypertension, antithyroid drugs, or thyroid hormone preparations. |
| PubMedID- 25661661 | Exclusion of these is likely to underestimate the benefit from any preventative intervention and thus underestimate the cost-effectiveness (that is, overestimate the icer), particularly in the longer term as patients avoid cardiovascular disease and live with diabetes long enough to develop microvascular complications. |
| PubMedID- 24094079 | The risk of cardiovascular disease in diabetes mellitus is pushed sharply higher by hypercholesterolemia, especially elevated low-density lipoprotein cholesterol (ldl-c). |
| PubMedID- 23284911 | Thus, therapeutic inhibition and prevention of microvascular diseases associated with diabetes could be addressed using apoedp to inhibit heparanase activation. |