PedAM

Pediatric Disease Annotations & Medicines


	wegener granulomatosis

Disease ID	250
Disease	wegener granulomatosis
Definition	multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic small vessel vasculitis; considered an aberrant hypersensitivity reaction to an unknown antigen.
Synonym	granulomatosis - wegener's granulomatosis wegener granulomatosis wegener's granulomatosis wegeners granulomatosis with polyangiitides granulomatosis with polyangiitis granulomatosis with polyangiitis (disorder) granulomatosis with polyangiitis [disease/finding] granulomatosis, necrotizing respiratory granulomatosis, wegener granulomatosis, wegener's necrotising respiratory granulomatosis necrotizing respiratory granulomatosis polyangiitides, granulomatosis with polyangiitis, granulomatosis with wegener syndrome wegener's granulomatosis wegener's granulomatosis (disorder) wegener's granulomatosis (disorder) [ambiguous] wegener's syndrome wegener's syndrome (disorder) wegeners granulomatosis wg with polyangiitides, granulomatosis with polyangiitis, granulomatosis
Orphanet	ORPHANET:900
OMIM	OMIM:608710
DOID	DOID:12132
UMLS	C3495801
MeSH	D014890
SNOMED-CT	SNOMEDCT_US_2016_09_01:195353004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:75) C0042384 \| vasculitis \| 8 C0017658 \| glomerulonephritis \| 5 C0003873 \| rheumatoid arthritis \| 5 C0022568 \| keratitis \| 4 C0003864 \| arthritis \| 3 C0039263 \| takayasu arteritis \| 3 C0019158 \| hepatitis \| 2 C0040583 \| tracheal stenosis \| 2 C0026946 \| fungal infection \| 2 C0022116 \| ischemia \| 2 C0030305 \| pancreatitis \| 2 C0031154 \| peritonitis \| 2 C0021845 \| bowel perforation \| 1 C0019163 \| hepatitis b \| 1 C0025064 \| mediastinitis \| 1 C0042769 \| virus infection \| 1 C0030499 \| parasitosis \| 1 C0339204 \| staphyloma \| 1 C0035302 \| retinal artery occlusion \| 1 C0036202 \| sarcoidosis \| 1 C1527336 \| sjogren's syndrome \| 1 C0015469 \| facial nerve paralysis \| 1 C0334268 \| schneiderian papilloma \| 1 C1744558 \| t cell deficiency \| 1 C0021845 \| intestinal perforation \| 1 C0151436 \| leukocytoclastic vasculitis \| 1 C0151744 \| myocardial ischemia \| 1 C0032326 \| pneumothorax \| 1 C0403416 \| crescentic glomerulonephritis \| 1 C0018784 \| sensorineural hearing loss \| 1 C0027051 \| myocardial infarction \| 1 C0019196 \| hepatitis c \| 1 C0022660 \| acute renal failure \| 1 C0270612 \| leukoencephalopathy \| 1 C0334121 \| inflammatory pseudotumour \| 1 C0018202 \| granulomatous vasculitis \| 1 C0027813 \| neuritis \| 1 C0409974 \| lupus erythematosus \| 1 C0028432 \| nasal disease \| 1 C0001339 \| acute pancreatitis \| 1 C0014118 \| endocarditis \| 1 C0242343 \| panhypopituitarism \| 1 C0020255 \| hydrocephalus \| 1 C0004623 \| bacterial infection \| 1 C0042384 \| angiitis \| 1 C0038220 \| status epilepticus \| 1 C0027697 \| nephritis \| 1 C0027059 \| myocarditis \| 1 C0154733 \| multiple cranial nerve palsies \| 1 C0011847 \| diabetes \| 1 C0010346 \| crohn's disease \| 1 C0035333 \| retinitis \| 1 C0004153 \| atherosclerosis \| 1 C0024141 \| systemic lupus erythematosus \| 1 C0035455 \| rhinitis \| 1 C0017160 \| gastroenteritis \| 1 C0027051 \| myocardial infarct \| 1 C0206178 \| cytomegalovirus retinitis \| 1 C0010051 \| coronary artery aneurysm \| 1 C0021053 \| immune disease \| 1 C0034065 \| pulmonary embolism \| 1 C0005684 \| bladder cancer \| 1 C1145670 \| respiratory failure \| 1 C0005716 \| blastomycosis \| 1 C0007688 \| central retinal artery occlusion \| 1 C0010051 \| coronary artery aneurysms \| 1 C0015230 \| rash \| 1 C0008526 \| choroiditis \| 1 C0003504 \| aortic regurgitation \| 1 C0010414 \| cryptococcosis \| 1 C0023890 \| cirrhosis \| 1 C0015469 \| facial paralysis \| 1 C0026718 \| mucormycosis \| 1 C0035078 \| renal failure \| 1 C0029134 \| optic neuritis \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:5) CTLA4 \| 1493 \| ORPHANET HLA-DPB1 \| 3115 \| GWASCAT;GHR;ORPHANET PTPN22 \| 26191 \| ORPHANET PRTN3 \| 5657 \| CTD_human;ORPHANET FCGR3B \| 2215 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:35) 5657 \| PRTN3 \| infer 1636 \| ACE \| infer 2205 \| FCER1A \| infer 3115 \| HLA-DPB1 \| infer 3586 \| IL10 \| infer 4193 \| MDM2 \| infer 2206 \| MS4A2 \| infer 64127 \| NOD2 \| infer 5133 \| PDCD1 \| infer 5054 \| SERPINE1 \| infer 7040 \| TGFB1 \| infer 7157 \| TP53 \| infer 5465 \| PPARA \| infer 5468 \| PPARG \| infer 6257 \| RXRB \| infer 727 \| C5 \| infer 6366 \| CCL21 \| infer 6352 \| CCL5 \| infer 1234 \| CCR5 \| infer 958 \| CD40 \| infer 1021 \| CDK6 \| infer 1493 \| CTLA4 \| infer 3119 \| HLA-DQB1 \| infer 3458 \| IFNG \| infer 59067 \| IL21 \| infer 3560 \| IL2RB \| infer 3798 \| KIF5A \| infer 11278 \| KLF12 \| infer 79258 \| MMEL1 \| infer 5588 \| PRKCQ \| infer 26191 \| PTPN22 \| infer 6775 \| STAT4 \| infer 7124 \| TNF \| infer 7128 \| TNFAIP3 \| infer 7185 \| TRAF1 \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:110) 50 \| ACO2 \| DISEASES 1511 \| CTSG \| DISEASES 10544 \| PROCR \| DISEASES 8797 \| TNFRSF10A \| DISEASES 973 \| CD79A \| DISEASES 4353 \| MPO \| DISEASES 6347 \| CCL2 \| DISEASES 3558 \| IL2 \| DISEASES 969 \| CD69 \| DISEASES 3458 \| IFNG \| DISEASES 9450 \| LY86 \| DISEASES 23438 \| HARS2 \| DISEASES 3565 \| IL4 \| DISEASES 566 \| AZU1 \| DISEASES 5657 \| PRTN3 \| DISEASES 6402 \| SELL \| DISEASES 1088 \| CEACAM8 \| DISEASES 22933 \| SIRT2 \| DISEASES 968 \| CD68 \| DISEASES 2006 \| ELN \| DISEASES 55821 \| ALLC \| DISEASES 1401 \| CRP \| DISEASES 3568 \| IL5RA \| DISEASES 3569 \| IL6 \| DISEASES 1318 \| SLC31A2 \| DISEASES 10068 \| IL18BP \| DISEASES 9360 \| PPIG \| DISEASES 4069 \| LYZ \| DISEASES 7450 \| VWF \| DISEASES 671 \| BPI \| DISEASES 5588 \| PRKCQ \| DISEASES 3553 \| IL1B \| DISEASES 1991 \| ELANE \| DISEASES 943 \| TNFRSF8 \| DISEASES 941 \| CD80 \| DISEASES 3383 \| ICAM1 \| DISEASES 84920 \| ALG10 \| DISEASES 2212 \| FCGR2A \| DISEASES 90523 \| MLIP \| DISEASES 6291 \| SAA4 \| DISEASES 10666 \| CD226 \| DISEASES 23643 \| LY96 \| DISEASES 1234 \| CCR5 \| DISEASES 7412 \| VCAM1 \| DISEASES 2215 \| FCGR3B \| DISEASES 7123 \| CLEC3B \| DISEASES 10501 \| SEMA6B \| DISEASES 53342 \| IL17D \| DISEASES 3688 \| ITGB1 \| DISEASES 51181 \| DCXR \| DISEASES 1493 \| CTLA4 \| DISEASES 375611 \| SLC26A5 \| DISEASES 54205 \| CYCS \| DISEASES 27087 \| B3GAT1 \| DISEASES 144245 \| ALG10B \| DISEASES 6670 \| SP3 \| DISEASES 8639 \| AOC3 \| DISEASES 10294 \| DNAJA2 \| DISEASES 79966 \| SCD5 \| DISEASES 8411 \| EEA1 \| DISEASES 6605 \| SMARCE1 \| DISEASES 9235 \| IL32 \| DISEASES 1606 \| DGKA \| DISEASES 6401 \| SELE \| DISEASES 23583 \| SMUG1 \| DISEASES 445329 \| SULT1A4 \| DISEASES 2359 \| FPR3 \| DISEASES 6818 \| SULT1A3 \| DISEASES 51077 \| FCF1 \| DISEASES 5359 \| PLSCR1 \| DISEASES 538 \| ATP7A \| DISEASES 5265 \| SERPINA1 \| DISEASES 6775 \| STAT4 \| DISEASES 26191 \| PTPN22 \| DISEASES 114836 \| SLAMF6 \| DISEASES 117145 \| THEM4 \| DISEASES 2209 \| FCGR1A \| DISEASES 1847 \| DUSP5 \| DISEASES 959 \| CD40LG \| DISEASES 1043 \| CD52 \| DISEASES 6015 \| RING1 \| DISEASES 6257 \| RXRB \| DISEASES 10673 \| TNFSF13B \| DISEASES 50943 \| FOXP3 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 1041 \| CDSN \| DISEASES 7056 \| THBD \| DISEASES 11278 \| KLF12 \| DISEASES 57126 \| CD177 \| DISEASES 79258 \| MMEL1 \| DISEASES 7293 \| TNFRSF4 \| DISEASES 51374 \| ATRAID \| DISEASES 1992 \| SERPINB1 \| DISEASES 1854 \| DUT \| DISEASES 55858 \| TMEM165 \| DISEASES 10321 \| CRISP3 \| DISEASES 7124 \| TNF \| DISEASES 4049 \| LTA \| DISEASES 3115 \| HLA-DPB1 \| DISEASES 3920 \| LAMP2 \| DISEASES 3586 \| IL10 \| DISEASES 3850 \| KRT3 \| DISEASES 51428 \| DDX41 \| DISEASES 342538 \| NACA2 \| DISEASES 22999 \| RIMS1 \| DISEASES 56674 \| TMEM9B \| DISEASES 727897 \| MUC5B \| DISEASES 83695 \| RHNO1 \| DISEASES 3684 \| ITGAM \| DISEASES 27229 \| TUBGCP4 \| DISEASES
Locus	(Waiting for update.)

Disease ID	250
Disease	wegener granulomatosis
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:1) HP:0002955 \| Granulomatosis
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:63) HP:0002955 \| Granulomatosis \| 66 HP:0002633 \| Vasculitis \| 9 HP:0001607 \| Subglottic stenosis \| 6 HP:0000099 \| Glomerular nephritis \| 5 HP:0001370 \| Rheumatoid arthritis \| 5 HP:0000491 \| Corneal inflammation \| 4 HP:0001369 \| Arthritis \| 3 HP:0002777 \| Tracheal stenosis \| 2 HP:0030250 \| Pulmonary granulomatosis \| 2 HP:0012115 \| Liver inflammation \| 2 HP:0006824 \| Cranial nerve palsy \| 2 HP:0001733 \| Pancreatic inflammation \| 2 HP:0012384 \| Nasal inflammation \| 2 HP:0002586 \| Peritonitis \| 2 HP:0100533 \| Ocular inflammation \| 1 HP:0012819 \| Myocarditis \| 1 HP:0000871 \| Panhypopituitarism \| 1 HP:0009725 \| Bladder neoplasm \| 1 HP:0005206 \| Pancreatic pseudocyst \| 1 HP:0100280 \| Morbus Crohn \| 1 HP:0002027 \| Abdominal pain \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0012531 \| Pain \| 1 HP:0012223 \| Ruptured spleen \| 1 HP:0000421 \| Bloody nose \| 1 HP:0001945 \| Fever \| 1 HP:0000155 \| Oral ulcer \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0100806 \| Sepsis \| 1 HP:0002138 \| Subarachnoid hemorrhage \| 1 HP:0000123 \| Nephritis \| 1 HP:0030171 \| Perirenal hematoma \| 1 HP:0002239 \| Gastrointestinal hemorrhage \| 1 HP:0002617 \| Aneurysmal dilatation \| 1 HP:0100773 \| Cartilage destruction \| 1 HP:0002107 \| Collapsed lung \| 1 HP:0002725 \| Systemic lupus erythematosus \| 1 HP:0002098 \| Respiratory distress \| 1 HP:0000407 \| sensorineural hearing loss \| 1 HP:0001658 \| Myocardial infarction \| 1 HP:0001394 \| Hepatic cirrhosis \| 1 HP:0200026 \| Ocular pain \| 1 HP:0002621 \| Atherosclerosis \| 1 HP:0030854 \| Scleral staphyloma \| 1 HP:0001659 \| Aortic insufficiency \| 1 HP:0002133 \| Status epilepticus \| 1 HP:0001114 \| Fatty deposits on eyelids \| 1 HP:0100653 \| Optic neuritis \| 1 HP:0008653 \| Crescentic glomerulonephritis \| 1 HP:0002108 \| Spontaneous pneumothorax \| 1 HP:0006859 \| Posterior leukoencephalopathy \| 1 HP:0000238 \| Nonsyndromal hydrocephalus \| 1 HP:0002352 \| Leukoencephalopathy \| 1 HP:0000071 \| Narrowing of the ureter \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0002584 \| Intestinal hemorrhage \| 1 HP:0100584 \| Endocarditis \| 1 HP:0012123 \| Posterior uveitis \| 1 HP:0001735 \| Acute pancreatitis \| 1 HP:0002878 \| Respiratory failure \| 1 HP:0007209 \| Facial paresis \| 1 HP:0010628 \| Facial palsy, unilateral or bilateral \| 1 HP:0001342 \| Intracerebral hemorrhage \| 1

Disease ID	250
Disease	wegener granulomatosis
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:39) C0009814 \| stenosis \| 9 C0042384 \| vasculitis \| 8 C0017658 \| glomerulonephritis \| 5 C1562901 \| peripheral ulcerative keratitis \| 3 C0040583 \| tracheal stenosis \| 2 C0019080 \| hemorrhage \| 2 C0022116 \| ischemia \| 2 C0019158 \| hepatitis \| 2 C0009450 \| infection \| 1 C0149745 \| oral ulcer \| 1 C0027547 \| necrotizing scleritis \| 1 C0151744 \| myocardial ischemia \| 1 C0018784 \| sensorineural hearing loss \| 1 C0014118 \| endocarditis \| 1 C0032326 \| pneumothorax \| 1 C0748164 \| multiple pulmonary nodules \| 1 C0403416 \| crescentic glomerulonephritis \| 1 C0021845 \| intestinal perforation \| 1 C1318520 \| necrotizing vasculitis \| 1 C0154733 \| multiple cranial nerve palsies \| 1 C0002940 \| aneurysms \| 1 C0004153 \| atherosclerosis \| 1 C0021308 \| infarction \| 1 C0149781 \| spontaneous pneumothorax \| 1 C0748159 \| pulmonary involvement \| 1 C0042384 \| angiitis \| 1 C0005684 \| bladder cancer \| 1 C0035333 \| retinitis \| 1 C0206178 \| cytomegalovirus retinitis \| 1 C0023890 \| cirrhosis \| 1 C0027051 \| myocardial infarction \| 1 C0016169 \| fistula \| 1 C0035302 \| retinal artery occlusion \| 1 C0007688 \| central retinal artery occlusion \| 1 C0010346 \| crohn's disease \| 1 C0267373 \| intestinal bleeding \| 1 C1384666 \| hearing loss \| 1 C0155210 \| xanthelasma \| 1 C0549143 \| pulmonary renal syndrome \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:1)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs9277554	23740775	3115	HLA-DPB1	umls:C3495801	GWASCAT	Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.	0.122367032	2013	HLA-DPB1	6	33087761	C	T

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:12)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
2	134540328	rs7585252	A	G	rs7585252	23740775	1.74E-05	NA	1.26	[1.13-1.40]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs7585252-G	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
4	183751029	rs4862110	T	C	rs4862110	23740775	2.00E-06	NA	1.44	[1.24-1.67]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs4862110-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	115759490	rs26595	G	A	rs26595	23740775	2.00E-08	NA	1.35	[1.22-1.49]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs26595-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
5	152636793	rs10515687	C	T	rs10515687	23740775	3.01E-04	NA	1.35	[1.15-1.59]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs10515687-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	33039625	rs9277341	T	C	rs9277341	23740775	2.18E-39	NA	3.03	[2.56-3.57]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs9277341-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
6	33055538	rs9277554	C	T	rs9277554	23740775	2.00E-50	NA	4.17	[3.33-5.00]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs9277554-C	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
7	51537887	rs1949829	C	T	rs1949829	23740775	4.00E-07	NA	1.78	[1.42-2.24]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs1949829-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
9	138468394	rs705669	C	T	rs705669	23740775	2.52E-05	NA	1.3	[1.15-1.47]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs705669-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	A
11	60592276	rs595018	T	C	rs595018	23740775	2.00E-07	NA	1.46	[1.27-1.69]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs595018-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G
17	6141677	rs7503953	A	C	rs7503953	23740775	2.00E-07	NA	1.5	[1.29-1.76]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs7503953-A	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	C
20	955412	rs6140836	T	C	rs6140836	23740775	7.09E-04	NA	1.33	[1.12-1.58]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs6140836-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	T
20	53458805	rs6023640	T	G	rs6023640	23740775	2.73E-05	NA	1.29	[1.14-1.45]	459 European ancestry cases; 1,503 European ancestry controls	European(1962)	ALL(1962)	EUR(1962)	ALL(1962)	Wegener's granulomatosis	HPOID:0002955	Granulomatosis	DOID:12132	Wegener's granulomatosis	D014890	Wegener Granulomatosis	NA	NA	Vasculitis	rs6023640-T	Research Support, N.I.H., Extramural	Research Support, Non-U.S. Gov't	G

Mapped by lexical matching(Total Items:0)
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Mapped by homologous gene(Total Items:0)
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Chemical(Total Drugs:5)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C3495801	cyclophosphamide	D003520	50-18-0	granulomatosis with polyangiitis	MESH:D014890	therapeutic	11485512
C3495801	cyclosporine	D016572	59865-13-3	granulomatosis with polyangiitis	MESH:D014890	therapeutic	11485512
C3495801	mesna	D015080	19767-45-4	granulomatosis with polyangiitis	MESH:D014890	therapeutic	1353574
C3495801	methotrexate	D008727	1959/5/2	granulomatosis with polyangiitis	MESH:D014890	therapeutic	18592451
C3495801	propylthiouracil	D011441	51-52-5	granulomatosis with polyangiitis	MESH:D014890	marker/mechanism	9806373

FDA approved drug and dosage information(Total Drugs:0)
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FDA labeling changes(Total Drugs:0)
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