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PedAM

Pediatric Disease Annotations & Medicines



   wallerian degeneration
  

Disease ID 1708
Disease wallerian degeneration
Definition
Degeneration of distal aspects of a nerve axon following injury to the cell body or proximal portion of the axon. The process is characterized by fragmentation of the axon and its MYELIN SHEATH.
Synonym
degeneration secondary
degeneration, wallerian
secondary degeneration
wallerian degeneration (morphologic abnormality)
wallerian degeneration [disease/finding]
UMLS
C0043020
MeSH
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:5)
C0442874  |  neuropathy  |  2
C0270921  |  axonal neuropathy  |  1
C0270612  |  leukoencephalopathy  |  1
C0023524  |  progressive multifocal leukoencephalopathy  |  1
C0026846  |  muscle wasting  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:2)
SIRT1  |  23411  |  CTD_human
CCAR2  |  57805  |  CTD_human
Inferring Gene(Waiting for update.)
Text Mined Gene(Waiting for update.)
Locus(Waiting for update.)
Disease ID 1708
Disease wallerian degeneration
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:7)
Disease ID 1708
Disease wallerian degeneration
Manually Symptom(Waiting for update.)
Text Mined Symptom(Waiting for update.)
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:1)
CUI ChemicalName ChemicalID CasRN DiseaseName DiseaseID DirectEvidence PubMedIDs
C0043020vincristineD014750-wallerian degenerationMESH:D014855marker/mechanism539376
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)