All Snps(Total Genotypes:22) |
|---|
| snpId |
pubmedId |
geneId |
geneSymbol |
diseaseId |
sourceId |
sentence |
score |
Year |
geneSymbol_dbSNP |
CHROMOSOME |
POS |
REF |
ALT |
| rs12252 | 23361009 | 10410 | IFITM3 | umls:C0042769 | BeFree | The SNP rs12252-C allele alters the function of interferon-induced transmembrane protein-3 increasing the disease severity of influenza virus infection in Caucasians, but the allele is rare. | 0.001357209 | 2013 | IFITM3 | 11 | 320772 | A | G |
| rs12487066 | 25261476 | 3447 | IFNA13 | umls:C0042769 | BeFree | Our data suggest a role of the CBLB rs12487066 variant in the interactions of a genetic risk factor and IFN function during viral infections in MS. | 0.022258234 | 2015 | LOC105374027 | 3 | 106193283 | T | C |
| rs12979860 | 24204859 | 282617 | IFNL3 | umls:C0042769 | BeFree | Association of IFNL3 rs12979860 and rs8099917 with biochemical predictors of interferon responsiveness in chronic hepatitis C virus infection. | 0.009500466 | 2013 | IFNL3;IFNL4 | 19 | 39248147 | C | T |
| rs12979860 | 25897598 | 282617 | IFNL3 | umls:C0042769 | BeFree | The interleukin-28B (IL28B) gene contains a single-nucleotide polymorphism at location rs12979860 that affects both the natural history of hepatitis C virus infection and the patient's response to treatment, particularly interferon-based regimens with or without protease inhibitors. | 0.009500466 | 2015 | IFNL3;IFNL4 | 19 | 39248147 | C | T |
| rs17886084 | 23941979 | 5054 | SERPINE1 | umls:C0042769 | BeFree | The aim of this work was to establish an association between the single-nucleotide polymorphisms (SNPs) of TGFB1 (rs1800471), AT (rs3789679), MMP-1 (rs17886084), MMP-3 (rs35068180), and PAI-1 (rs1799889) and the histological grading of necroinflammation, staging of hepatic fibrosis, and liver function in Mexican patients with advanced liver fibrosis due to chronic hepatitis C virus infection. | 0.001085767 | 2014 | NA | NA | NA | NA | NA |
| rs179008 | 20872712 | 51284 | TLR7 | umls:C0042769 | BeFree | Toll-like receptor 7 rs179008/Gln11Leu gene variants in chronic hepatitis C virus infection. | 0.004810009 | 2010 | TLR7 | X | 12885540 | A | C,T |
| rs1799864 | 17465499 | 729230 | CCR2 | umls:C0042769 | BeFree | CCL2-2518 A/G and CCR2 190 A/G do not influence the outcome of hepatitis C virus infection in the Spanish population. | 0.000542884 | 2007 | CCR2 | 3 | 46357717 | G | A |
| rs1799889 | 23941979 | 5054 | SERPINE1 | umls:C0042769 | BeFree | The aim of this work was to establish an association between the single-nucleotide polymorphisms (SNPs) of TGFB1 (rs1800471), AT (rs3789679), MMP-1 (rs17886084), MMP-3 (rs35068180), and PAI-1 (rs1799889) and the histological grading of necroinflammation, staging of hepatic fibrosis, and liver function in Mexican patients with advanced liver fibrosis due to chronic hepatitis C virus infection. | 0.001085767 | 2014 | SERPINE1 | 7 | 101126430 | A | G |
| rs1800471 | 23941979 | 5054 | SERPINE1 | umls:C0042769 | BeFree | The aim of this work was to establish an association between the single-nucleotide polymorphisms (SNPs) of TGFB1 (rs1800471), AT (rs3789679), MMP-1 (rs17886084), MMP-3 (rs35068180), and PAI-1 (rs1799889) and the histological grading of necroinflammation, staging of hepatic fibrosis, and liver function in Mexican patients with advanced liver fibrosis due to chronic hepatitis C virus infection. | 0.001085767 | 2014 | TGFB1 | 19 | 41352971 | C | G |
| rs1800477 | 21159314 | 596 | BCL2 | umls:C0042769 | BeFree | BCL-2 gene polymorphism at codon 43 (127G/A) has been found to be a reliable and sensitive marker for the prediction of response to interferon therapy during viral infections. | 0.002985861 | 2011 | BCL2 | 18 | 63318540 | C | T |
| rs1800562 | 17062032 | 3077 | HFE | umls:C0042769 | BeFree | The prevalence of HFE C282Y gene mutation is increased in Spanish patients with porphyria cutanea tarda without hepatitis C virus infection. | 0.001628651 | 2006 | HFE | 6 | 26092913 | G | A |
| rs35068180 | 23941979 | 5054 | SERPINE1 | umls:C0042769 | BeFree | The aim of this work was to establish an association between the single-nucleotide polymorphisms (SNPs) of TGFB1 (rs1800471), AT (rs3789679), MMP-1 (rs17886084), MMP-3 (rs35068180), and PAI-1 (rs1799889) and the histological grading of necroinflammation, staging of hepatic fibrosis, and liver function in Mexican patients with advanced liver fibrosis due to chronic hepatitis C virus infection. | 0.001085767 | 2014 | MMP3 | 11 | 102845216 | - | A,AA |
| rs3775291 | 22174453 | 7098 | TLR3 | umls:C0042769 | BeFree | Genetic association studies have provided evidence concerning the role of a polymorphism in TLR3 (rs3775291, Leu412Phe) in viral infection susceptibility. | 0.011053172 | 2012 | TLR3 | 4 | 186082920 | C | T,G |
| rs3789679 | 23941979 | 5054 | SERPINE1 | umls:C0042769 | BeFree | The aim of this work was to establish an association between the single-nucleotide polymorphisms (SNPs) of TGFB1 (rs1800471), AT (rs3789679), MMP-1 (rs17886084), MMP-3 (rs35068180), and PAI-1 (rs1799889) and the histological grading of necroinflammation, staging of hepatic fibrosis, and liver function in Mexican patients with advanced liver fibrosis due to chronic hepatitis C virus infection. | 0.001085767 | 2014 | AGT | 1 | 230713948 | G | A |
| rs3806798 | 24762213 | 3600 | IL15 | umls:C0042769 | BeFree | A promoter polymorphism (rs3806798) of interleukin-15 gene is associated with chronic hepatitis B virus infection in the Chinese Han population. | 0.001900093 | 2014 | IL15 | 4 | 141636126 | T | A |
| rs386586050 | 22174453 | 7098 | TLR3 | umls:C0042769 | BeFree | Genetic association studies have provided evidence concerning the role of a polymorphism in TLR3 (rs3775291, Leu412Phe) in viral infection susceptibility. | 0.011053172 | 2012 | NA | NA | NA | NA | NA |
| rs4804803 | 22061615 | 30835 | CD209 | umls:C0042769 | BeFree | Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene. | 0.001628651 | 2012 | CD209 | 19 | 7747847 | A | G |
| rs4986790 | 21443084 | 7099 | TLR4 | umls:C0042769 | BeFree | Polymorphisms of the toll-like receptor (TLR) 2 (Arg677Trp, Arg753Gln) and TLR4 (Asp299Gly, Thr399Ile) genes, which are important components of innate immunity against viral infection, have recently been described. | 0.005819831 | 2010 | TLR4 | 9 | 117713024 | A | G |
| rs4986791 | 21443084 | 7099 | TLR4 | umls:C0042769 | BeFree | Polymorphisms of the toll-like receptor (TLR) 2 (Arg677Trp, Arg753Gln) and TLR4 (Asp299Gly, Thr399Ile) genes, which are important components of innate immunity against viral infection, have recently been described. | 0.005819831 | 2010 | TLR4 | 9 | 117713324 | C | T |
| rs738409 | 22704398 | 80339 | PNPLA3 | umls:C0042769 | BeFree | Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) genetic variant has been associated with hepatocellular carcinoma (HCC) in individuals with chronic alcohol abuse or hepatic viral infection. | 0.000542884 | 2012 | PNPLA3 | 22 | 43928847 | C | G |
| rs8099917 | 22336134 | 282617 | IFNL3 | umls:C0042769 | BeFree | The genotyping and viral-serological analysis for 340 individuals showed that IL-28B genotype distribution of rs8099917 SNP did not differ significantly by respective viral infection status. | 0.009500466 | 2012 | NA | 19 | 39252525 | T | G |
| rs8099917 | 24204859 | 282617 | IFNL3 | umls:C0042769 | BeFree | Association of IFNL3 rs12979860 and rs8099917 with biochemical predictors of interferon responsiveness in chronic hepatitis C virus infection. | 0.009500466 | 2013 | NA | 19 | 39252525 | T | G |
