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PedAM

Pediatric Disease Annotations & Medicines



   venous insufficiency
  

Disease ID 1459
Disease venous insufficiency
Definition
Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle.
Synonym
insufficiencies, venous
insufficiency venous
insufficiency, venous
peripheral venous insufficiency
peripheral venous insufficiency (disorder)
peripheral venous insufficiency, nos
peripheral venous insufficiency, unspecified
venous (peripheral) insufficiency, unspecified
venous insufficiencies
venous insufficiency [disease/finding]
venous insufficiency nos
venous insufficiency, unspecified
DOID
UMLS
C0042485
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:17)
C0026769  |  multiple sclerosis  |  33
C0020538  |  hypertension  |  6
C0011603  |  dermatitis  |  4
C0042345  |  varicose veins  |  2
C0042345  |  varicose vein  |  2
C0235522  |  venous disease  |  1
C0022116  |  ischemia  |  1
C0042345  |  varices  |  1
C0025281  |  meniere's disease  |  1
C0030326  |  panniculitis  |  1
C0042345  |  varicosities  |  1
C0852949  |  arterial disease  |  1
C0040046  |  thrombophlebitis  |  1
C0024236  |  lymphedema  |  1
C0037274  |  dermatosis  |  1
C1704436  |  peripheral arterial disease  |  1
C0040053  |  thrombosis  |  1
Curated Gene(Waiting for update.)
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:1)
5054  |  SERPINE1  |  infer
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:122)
2273  |  FHL1  |  DISEASES
9817  |  KEAP1  |  DISEASES
1361  |  CPB2  |  DISEASES
9552  |  SPAG7  |  DISEASES
266  |  AMELY  |  DISEASES
3053  |  SERPIND1  |  DISEASES
7076  |  TIMP1  |  DISEASES
4313  |  MMP2  |  DISEASES
5327  |  PLAT  |  DISEASES
8529  |  CYP4F2  |  DISEASES
7040  |  TGFB1  |  DISEASES
1577  |  CYP3A5  |  DISEASES
5054  |  SERPINE1  |  DISEASES
6347  |  CCL2  |  DISEASES
6402  |  SELL  |  DISEASES
7276  |  TTR  |  DISEASES
27019  |  DNAI1  |  DISEASES
8189  |  SYMPK  |  DISEASES
7429  |  VIL1  |  DISEASES
7425  |  VGF  |  DISEASES
968  |  CD68  |  DISEASES
27112  |  FAM155B  |  DISEASES
1401  |  CRP  |  DISEASES
8739  |  HRK  |  DISEASES
3569  |  IL6  |  DISEASES
9360  |  PPIG  |  DISEASES
7450  |  VWF  |  DISEASES
6521  |  SLC4A1  |  DISEASES
25939  |  SAMHD1  |  DISEASES
3553  |  IL1B  |  DISEASES
6403  |  SELP  |  DISEASES
54431  |  DNAJC10  |  DISEASES
3004  |  GZMM  |  DISEASES
8626  |  TP63  |  DISEASES
3383  |  ICAM1  |  DISEASES
3827  |  KNG1  |  DISEASES
11081  |  KERA  |  DISEASES
50511  |  SYCP3  |  DISEASES
4841  |  NONO  |  DISEASES
50853  |  VILL  |  DISEASES
10694  |  CCT8  |  DISEASES
6352  |  CCL5  |  DISEASES
7412  |  VCAM1  |  DISEASES
9076  |  CLDN1  |  DISEASES
213  |  ALB  |  DISEASES
8927  |  BSN  |  DISEASES
6632  |  SNRPD1  |  DISEASES
4597  |  MVD  |  DISEASES
81620  |  CDT1  |  DISEASES
4054  |  LTBP3  |  DISEASES
285335  |  SLC9C1  |  DISEASES
1473  |  CST5  |  DISEASES
2147  |  F2  |  DISEASES
5340  |  PLG  |  DISEASES
56945  |  MRPS22  |  DISEASES
1579  |  CYP4A11  |  DISEASES
124535  |  HSF5  |  DISEASES
51228  |  GLTP  |  DISEASES
4312  |  MMP1  |  DISEASES
5366  |  PMAIP1  |  DISEASES
2303  |  FOXC2  |  DISEASES
716  |  C1S  |  DISEASES
5580  |  PRKCD  |  DISEASES
6401  |  SELE  |  DISEASES
25825  |  BACE2  |  DISEASES
55742  |  PARVA  |  DISEASES
2152  |  F3  |  DISEASES
7430  |  EZR  |  DISEASES
113675  |  SDSL  |  DISEASES
23463  |  ICMT  |  DISEASES
2701  |  GJA4  |  DISEASES
51077  |  FCF1  |  DISEASES
6275  |  S100A4  |  DISEASES
23481  |  PES1  |  DISEASES
51322  |  WAC  |  DISEASES
5789  |  PTPRD  |  DISEASES
219844  |  HYLS1  |  DISEASES
3683  |  ITGAL  |  DISEASES
23607  |  CD2AP  |  DISEASES
2157  |  F8  |  DISEASES
23038  |  WDTC1  |  DISEASES
57165  |  GJC2  |  DISEASES
462  |  SERPINC1  |  DISEASES
4921  |  DDR2  |  DISEASES
9557  |  CHD1L  |  DISEASES
8277  |  TKTL1  |  DISEASES
282991  |  BLOC1S2  |  DISEASES
1573  |  CYP2J2  |  DISEASES
7422  |  VEGFA  |  DISEASES
4318  |  MMP9  |  DISEASES
5328  |  PLAU  |  DISEASES
1759  |  DNM1  |  DISEASES
3055  |  HCK  |  DISEASES
4524  |  MTHFR  |  DISEASES
4693  |  NDP  |  DISEASES
9445  |  ITM2B  |  DISEASES
646480  |  FABP9  |  DISEASES
1906  |  EDN1  |  DISEASES
3045  |  HBD  |  DISEASES
265  |  AMELX  |  DISEASES
9189  |  ZBED1  |  DISEASES
114899  |  C1QTNF3  |  DISEASES
51466  |  EVL  |  DISEASES
64333  |  ARHGAP9  |  DISEASES
5627  |  PROS1  |  DISEASES
126549  |  ANKLE1  |  DISEASES
3676  |  ITGA4  |  DISEASES
6611  |  SMS  |  DISEASES
57703  |  CWC22  |  DISEASES
720  |  C4A  |  DISEASES
7124  |  TNF  |  DISEASES
6635  |  SNRPE  |  DISEASES
3586  |  IL10  |  DISEASES
721  |  C4B  |  DISEASES
5542  |  PRB1  |  DISEASES
10189  |  ALYREF  |  DISEASES
727897  |  MUC5B  |  DISEASES
3684  |  ITGAM  |  DISEASES
8914  |  TIMELESS  |  DISEASES
100316868  |  HOTTIP  |  DISEASES
104564225  |  MHRT  |  DISEASES
26770  |  SNORD79  |  DISEASES
Locus(Waiting for update.)
Disease ID 1459
Disease venous insufficiency
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:15)
HP:0000969  |  Dropsy  |  7
HP:0000822  |  Hypertension  |  6
HP:0002619  |  Varicose veins  |  2
HP:0002625  |  Blood clot in a deep vein  |  2
HP:0010741  |  Peripheral edema of lower extremity  |  2
HP:0002459  |  Dysautonomia  |  1
HP:0100543  |  Cognitive deficits  |  1
HP:0004418  |  Thrombophlebitis  |  1
HP:0001004  |  Lymphatic obstruction  |  1
HP:0012531  |  Pain  |  1
HP:0000958  |  Xerosis  |  1
HP:0001785  |  Ankle swelling  |  1
HP:0012490  |  Inflammation of fat tissue  |  1
HP:0100758  |  Gangrene  |  1
HP:0004950  |  Peripheral artery disease  |  1
Disease ID 1459
Disease venous insufficiency
Manually Symptom(Waiting for update.)
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:2)
C0023223  |  leg ulcers  |  5
C0235886  |  leg edema  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Chemical(Total Drugs:0)
(Waiting for update.)
FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)
FDA labeling changes(Total Drugs:0)
(Waiting for update.)