PedAM

Pediatric Disease Annotations & Medicines


	umbilical hernia

Disease ID	1542
Disease	umbilical hernia
Definition	Protrusion of the abdominal cavity contents through the abdominal wall at the umbilicus.
Synonym	hernia - umbilical hernia umbilical hernia, umbilical umbilical hernia (disorder) umbilical hernia nos umbilical hernia nos (disorder) umbilical hernia, nos umbilical hernias unspecified umbilical hernia unspecified umbilical hernia (disorder) unspecified umbilical hernia nos unspecified umbilical hernia nos (disorder)
DOID	DOID:0060321
UMLS	C0019322
MeSH	D006554
SNOMED-CT	SNOMEDCT_US_2016_09_01:396347007
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:22) C0023890 \| cirrhosis \| 11 C0023890 \| liver cirrhosis \| 10 C0023895 \| liver disease \| 3 C0014175 \| endometriosis \| 2 C0031154 \| peritonitis \| 1 C0346109 \| peritoneal mesothelioma \| 1 C0346109 \| malignant peritoneal mesothelioma \| 1 C0016977 \| gallbladder disease \| 1 C0376358 \| prostate cancer \| 1 C0022679 \| cystic kidney \| 1 C0085413 \| autosomal dominant polycystic kidney \| 1 C0022658 \| kidney disease \| 1 C0025362 \| mental retardation \| 1 C0003615 \| appendicitis \| 1 C0023890 \| hepatic cirrhosis \| 1 C0019291 \| hiatal hernia \| 1 C0020541 \| portal hypertension \| 1 C0021843 \| bowel obstruction \| 1 C0008350 \| cholelithiasis \| 1 C0025037 \| meckel's diverticulum \| 1 C0085413 \| autosomal dominant polycystic kidney disease \| 1 C0019294 \| inguinal hernia \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:100) 6793 \| STK10 \| DISEASES 5351 \| PLOD1 \| DISEASES 7051 \| TGM1 \| DISEASES 3956 \| LGALS1 \| DISEASES 2999 \| GZMH \| DISEASES 140679 \| SLC32A1 \| DISEASES 7038 \| TG \| DISEASES 4232 \| MEST \| DISEASES 4656 \| MYOG \| DISEASES 5266 \| PI3 \| DISEASES 7389 \| UROD \| DISEASES 5199 \| CFP \| DISEASES 3425 \| IDUA \| DISEASES 3630 \| INS \| DISEASES 6299 \| SALL1 \| DISEASES 9509 \| ADAMTS2 \| DISEASES 80896 \| NPL \| DISEASES 23314 \| SATB2 \| DISEASES 2660 \| MSTN \| DISEASES 1387 \| CREBBP \| DISEASES 119 \| ADD2 \| DISEASES 7474 \| WNT5A \| DISEASES 1788 \| DNMT3A \| DISEASES 10686 \| CLDN16 \| DISEASES 80144 \| FRAS1 \| DISEASES 411 \| ARSB \| DISEASES 285362 \| SUMF1 \| DISEASES 60496 \| AASDHPPT \| DISEASES 341640 \| FREM2 \| DISEASES 8562 \| DENR \| DISEASES 10563 \| CXCL13 \| DISEASES 7547 \| ZIC3 \| DISEASES 374739 \| TEPP \| DISEASES 213 \| ALB \| DISEASES 10085 \| EDIL3 \| DISEASES 6228 \| RPS23 \| DISEASES 1278 \| COL1A2 \| DISEASES 9317 \| PTER \| DISEASES 84168 \| ANTXR1 \| DISEASES 121340 \| SP7 \| DISEASES 3603 \| IL16 \| DISEASES 5308 \| PITX2 \| DISEASES 649 \| BMP1 \| DISEASES 118429 \| ANTXR2 \| DISEASES 133522 \| PPARGC1B \| DISEASES 1909 \| EDNRA \| DISEASES 53347 \| UBASH3A \| DISEASES 9475 \| ROCK2 \| DISEASES 2193 \| FARSA \| DISEASES 51715 \| RAB23 \| DISEASES 811 \| CALR \| DISEASES 2200 \| FBN1 \| DISEASES 5324 \| PLAG1 \| DISEASES 64332 \| NFKBIZ \| DISEASES 23384 \| SPECC1L \| DISEASES 5178 \| PEG3 \| DISEASES 1946 \| EFNA5 \| DISEASES 6906 \| SERPINA7 \| DISEASES 29940 \| DSE \| DISEASES 27445 \| PCLO \| DISEASES 2626 \| GATA4 \| DISEASES 8788 \| DLK1 \| DISEASES 5498 \| PPOX \| DISEASES 54898 \| ELOVL2 \| DISEASES 5325 \| PLAGL1 \| DISEASES 273 \| AMPH \| DISEASES 3482 \| IGF2R \| DISEASES 2571 \| GAD1 \| DISEASES 84867 \| PTPN5 \| DISEASES 7048 \| TGFBR2 \| DISEASES 26580 \| BSCL2 \| DISEASES 4512 \| MT-CO1 \| DISEASES 9851 \| KIAA0753 \| DISEASES 79577 \| CDC73 \| DISEASES 2778 \| GNAS \| DISEASES 9124 \| PDLIM1 \| DISEASES 10555 \| AGPAT2 \| DISEASES 2304 \| FOXE1 \| DISEASES 6668 \| SP2 \| DISEASES 347252 \| IGFBPL1 \| DISEASES 3980 \| LIG3 \| DISEASES 347527 \| ARSH \| DISEASES 9467 \| SH3BP5 \| DISEASES 831 \| CAST \| DISEASES 2737 \| GLI3 \| DISEASES 1781 \| DYNC1I2 \| DISEASES 2887 \| GRB10 \| DISEASES 6093 \| ROCK1 \| DISEASES 57057 \| TBX20 \| DISEASES 4776 \| NFATC4 \| DISEASES 3481 \| IGF2 \| DISEASES 7849 \| PAX8 \| DISEASES 117581 \| TWIST2 \| DISEASES 79827 \| CLMP \| DISEASES 389643 \| NUGGC \| DISEASES 1028 \| CDKN1C \| DISEASES 645073 \| GAGE12G \| DISEASES 9152 \| SLC6A5 \| DISEASES 149775 \| GNAS-AS1 \| DISEASES 10984 \| KCNQ1OT1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1542
Disease	umbilical hernia
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:23) HP:0001394 \| Hepatic cirrhosis \| 10 HP:0001541 \| Ascites \| 8 HP:0003270 \| Distended abdomen \| 3 HP:0100790 \| Hernia \| 3 HP:0012531 \| Pain \| 2 HP:0030127 \| Endometriosis \| 2 HP:0012223 \| Ruptured spleen \| 1 HP:0012618 \| Urachal cyst \| 1 HP:0002664 \| Neoplasia \| 1 HP:0100003 \| Peritoneal mesothelioma \| 1 HP:0000113 \| Polycystic kidney dysplasia \| 1 HP:0012125 \| Prostate cancer \| 1 HP:0002036 \| Hiatus hernia \| 1 HP:0002586 \| Peritonitis \| 1 HP:0200042 \| Skin ulcer \| 1 HP:0001409 \| Portal hypertension \| 1 HP:0000023 \| Inguinal hernia \| 1 HP:0004322 \| Stature below 3rd percentile \| 1 HP:0005214 \| Bowel obstruction \| 1 HP:0001081 \| Gallstones \| 1 HP:0001249 \| Mental retardation \| 1 HP:0010866 \| Congenital anterior abdominal wall defect \| 1 HP:0001540 \| Diastasis recti \| 1

Disease ID	1542
Disease	umbilical hernia
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:3) C0269120 \| umbilical endometriosis \| 2 C0041915 \| urachal cyst \| 1 C0003615 \| appendicitis \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:3)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0019322	phenytoin	D010672	57-41-0	hernia, umbilical	MESH:D006554	marker/mechanism	1163515
C0019322	thalidomide	D013792	50-35-1	hernia, umbilical	MESH:D006554	marker/mechanism	21505091
C0019322	vigabatrin	D020888	60643-86-9	hernia, umbilical	MESH:D006554	marker/mechanism	9181670

FDA approved drug and dosage information(Total Drugs:0)
(Waiting for update.)

FDA labeling changes(Total Drugs:0)
(Waiting for update.)

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