PedAM
Pediatric Disease Annotations & Medicines
| transverse myelitis | ||||
| Disease ID | 1179 |
|---|---|
| Disease | transverse myelitis |
| Definition | Inflammation of a transverse portion of the spinal cord characterized by acute or subacute segmental demyelination or necrosis. The condition may occur sporadically, follow an infection or vaccination, or present as a paraneoplastic syndrome (see also ENCEPHALOMYELITIS, ACUTE DISSEMINATED). Clinical manifestations include motor weakness, sensory loss, and incontinence. (Adams et al., Principles of Neurology, 6th ed, pp1242-6) |
| Synonym | myelitis transverse myelitis, transverse myelitis, transverse [disease/finding] transverse myelitis acute or subacute transverse myelitis nos transverse myelopathy syndrome transverse myelopathy syndrome (disorder) transverse myelopathy syndromes |
| UMLS | C0026976 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:29) C0027873 | neuromyelitis optica | 6 C0024141 | systemic lupus erythematosus | 3 C0011303 | demyelinating disease | 3 C0011303 | demyelinating diseases | 3 C0409974 | lupus erythematosus | 3 C0026975 | myelitis | 3 C0027813 | neuritis | 2 C0030486 | paraplegia | 2 C0029134 | optic neuritis | 2 C0085278 | antiphospholipid antibody syndrome | 1 C0042721 | viral hepatitis | 1 C0085273 | parvovirus b19 infection | 1 C0005697 | neurogenic bladder | 1 C0085278 | antiphospholipid syndrome | 1 C0235025 | motor neuropathy | 1 C0009782 | connective tissue disease | 1 C0019196 | viral hepatitis c | 1 C0024198 | lyme disease | 1 C0015230 | rash | 1 C0026848 | myopathy | 1 C0021400 | influenza | 1 C0042769 | viral infection | 1 C0037928 | myelopathy | 1 C0019196 | hepatitis c | 1 C0034372 | tetraplegia | 1 C0004943 | behcet's disease | 1 C0019158 | hepatitis | 1 C0021053 | immune disease | 1 C0003872 | psoriatic arthritis | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1179 |
|---|---|
| Disease | transverse myelitis |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:17) HP:0012486 | Inflammation of spinal cord | 3 HP:0100653 | Optic neuritis | 2 HP:0010550 | Paraplegia | 2 HP:0002725 | Systemic lupus erythematosus | 2 HP:0003613 | Antiphospholipid antibodies | 2 HP:0002960 | Autoimmune condition | 2 HP:0002445 | Paralysis of all four limbs | 1 HP:0012115 | Liver inflammation | 1 HP:0003198 | Myopathic changes | 1 HP:0100561 | Spinal cord lesion | 1 HP:0012531 | Pain | 1 HP:0000011 | Neurogenic bladder | 1 HP:0000016 | Urinary retention | 1 HP:0002540 | Inability to walk | 1 HP:0002196 | Myelopathy | 1 HP:0001907 | Thromboembolic disease | 1 HP:0006562 | Viral hepatitis | 1 |
| Disease ID | 1179 |
|---|---|
| Disease | transverse myelitis |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:12) C1963237 | insomnia C0752303 | urological manifestations C0521532 | diaphragmatic paresis C0278134 | sensory loss C0151740 | intracranial hypertension C0027030 | myiasis C0026848 | myopathy C0026838 | spasticity C0025289 | meningitis C0024141 | systemic lupus erythematosus C0022660 | acute renal failure C0007459 | neurogenic bladder |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:3) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
Chemical(Total Drugs:2) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| CUI | ChemicalName | ChemicalID | CasRN | DiseaseName | DiseaseID | DirectEvidence | PubMedIDs | ||
| C0026976 | methotrexate | D008727 | 1959/5/2 | myelitis, transverse | MESH:D009188 | marker/mechanism | 17304378 | ||
| C0026976 | vinblastine | D014747 | 865-21-4 | myelitis, transverse | MESH:D009188 | marker/mechanism | 4688040 | ||
FDA approved drug and dosage information(Total Drugs:0) | |
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| (Waiting for update.) | |
FDA labeling changes(Total Drugs:0) | |
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| (Waiting for update.) | |